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Lazareva L.A.

Kuban State Medical University of the Ministry of Health of Russian Federation

Elizbaryan I.S.

Kuban State Medical University

Azamatova S.A.

Kuban State Medical University of the Ministry of Health of Russian Federation;
Adyghe Republican Hearing Rehabilitation Center of State Budget Organization of Health of Republic of Adygea Adyghe Republican Clinical Hospital Adyghe Republican Center for Medical Rehabilitation

Muzaeva B.R.

Kuban State Medical University

Sushcheva N.A.

Kuban State Medical University

Triggers and predictors of development and formation of sensorineural hearing loss

Authors:

Lazareva L.A., Elizbaryan I.S., Azamatova S.A., Muzaeva B.R., Sushcheva N.A.

More about the authors

Journal: Russian Bulletin of Otorhinolaryngology. 2022;87(2): 34‑43

DOI: 10.17116/otorino20228702134

Read: 1991 times

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Table of contents

TRIGGERS AND PREDICTORS OF DEVELOPMENT AND FORMATION OF SENSORINEURAL HEARING LOSS
TRIGGERS AND PREDICTORS OF DEVELOPMENT AND FORMATION OF SENSORINEURAL HEARING LOSS

To cite this article:

Lazareva LA, Elizbaryan IS, Azamatova SA, Muzaeva BR, Sushcheva NA. Triggers and predictors of development and formation of sensorineural hearing loss. Russian Bulletin of Otorhinolaryngology. 2022;87(2):34‑43. (In Russ.)
https://doi.org/10.17116/otorino20228702134

Подписка 2026 Вестник оториноларингологии (Russian Bulletin of Otorhinolaryngology)
 
МСФ на ЯМ
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Abstract:

The purpose of the study is to review the results of scientific researches in recent years in an expanded interdisciplinary view of the problem of etiopathogenesis of sensorineural hearing loss, as well as the role of comorbidities and triggers in the formation of persistent changes in the audio-receiving part of the auditory analyzer.

Keywords:

sensorineural hearing loss
etiopathogenesis
concomitant pathology

Authors:

Lazareva L.A.

Kuban State Medical University of the Ministry of Health of Russian Federation

Elizbaryan I.S.

Kuban State Medical University

Azamatova S.A.

Kuban State Medical University of the Ministry of Health of Russian Federation;
Adyghe Republican Hearing Rehabilitation Center of State Budget Organization of Health of Republic of Adygea Adyghe Republican Clinical Hospital Adyghe Republican Center for Medical Rehabilitation

Muzaeva B.R.

Kuban State Medical University

Sushcheva N.A.

Kuban State Medical University

Received:

20.08.2021

Accepted:

14.09.2021

Close metadata

References:

  1. Brown CS, Emmett SD, Robler SK, Tucci DL. Global Hearing Loss Prevention. Otolaryngologic Clinics of North America. 2018;51(3):575-592.  https://doi.org/10.1016/j.otc.2018.01.006
  2. Lazareva LA, Sushcheva NA, Muzaeva BR, Abaev VK. Method of screening epidemiological research of sensorineural hearing disorders in adults and its application in optimization of treatment and rehabilitation measures. Rossiiskaya otorinolaringologiya. 2018;96(5):58-65. (In Russ.). https://doi.org/10.18692/1810-4800-2018-5-58-65
  3. Kosyakov SYa, Kirdeeva AI. Etiopathogenetic aspects of idiopathic sensorineural hearing loss. Vestnik otorinolaringologii. 2017;82(2):95-101. (In Russ.). https://doi.org/10.17116/otorino201681695-101
  4. Bommakanti K, Iyer JS, Stankovic KM. Cochlear histopathology in human genetic hearing loss: State of the science and future prospects. Hearing Research. 2019;382:107785. https://doi.org/10.1016/j.heares.2019.107785
  5. Raymond M, Walker E, Dave I, Dedhia K. Genetic testing for congenital non-syndromic sensorineural hearing loss. International Journal of Pediatric Otorhinolaryngology. 2019;124:68-75.  https://doi.org/10.1016/j.ijporl.2019.05.038
  6. Dror AA, Avraham KB. Hearing impairment: A panoply of genes and functions. Neuron. 2010;68(2):2933-3008. https://doi.org/10.1016/j.neuron.2010.10.011
  7. Niggemann P, György B, Chen ZY. Genome and base editing for genetic hearing loss. Hearing Research. 2020;394:107958. https://doi.org/10.1016/j.heares.2020.107958
  8. Yu YQ, Yang HA, Xiao M, Wang JW, Huang DY, Bhambhani Y, Sonnenberg L, Clark B, Jin YZ, Fu WN, Zhang J, Yu Q, Liang XT, Zhang M. Genetic Effects on Sensorineural Hearing Loss and Evidence-based Treatment for Sensorineural Hearing Loss. Chinese Medical Sciences Journal. 2015;30(3):179-188.  https://doi.org/10.1016/s1001-9294(15)30044-4
  9. Silbernagl S, Lang F. Color Atlas of Pathophysiology. M.: Prakticheskaya meditsina; 2019. (In Russ.).
  10. Koide Y, Teranishi M, Sugiura S, Uchida Y, Nishio N, Kato K, Otake H, Yoshida T, Otsuka R, Ando F, Shimokata H, Hasegawa Y, Nakashima T, Sone M. Association between Uncoupling Protein 2 Gene Ala55val Polymorphism and Sudden Sensorineural Hearing Loss. The Journal of International Advanced Otology. 2018;14(2):166-169.  https://doi.org/10.5152/iao.2018.5442
  11. Zhang X, Weng Y, Xu Y, Xiong H, Liang M, Zheng Y, Ou Y. Selected blood inflammatory and metabolic parameters predicted successive bilateral sudden sensorineural hearing loss. Disease Markers. 2019;2019:7165257. https://doi.org/10.1155/2019/7165257
  12. Glaznikov LA, Ponidelko SN, Govorun MI. The role of genetic mutations in the patents with the acquired forms of sensorineural impairment of hearing. Vestnik otorinolaringologii. 2012;74(4):37-39. (In Russ.).
  13. Cohen BE, Durstenfeld A, Roehm PC. Viral causes of hearing loss: a review for hearing health professionals. Trends in Hearing. 2014;18:2331216514541361. https://doi.org/10.1177/2331216514541361
  14. Dawood G, Klop D, Olivier E, Elliott H, Pillay M, Grimmer K. Nature and extent of hearing loss in HIV-infected children: A scoping review. International Journal of Pediatric Otorhinolaryngology. 2020;134:110036. https://doi.org/10.1016/j.ijporl.2020.110036
  15. Lantos PM, Hoffman K, Permar SR, Jackson P, Hughes BL, Swamy GK. Geographic Disparities in Cytomegalovirus Infection during Pregnancy. Journal of the Pediatric Infectious Diseases Society. 2017;6(3):55-61.  https://doi.org/10.1093/jpids/piw088
  16. Lantos PM, Permar SR, Hoffman K, Swamy GK. The Excess Burden of Cytomegalovirus in African American Communities: A Geospatial Analysis. Open Forum Infectious Diseases. 2015; 2(4):180.  https://doi.org/10.1093/ofid/ofv180
  17. Goderis J, Keymeulen A, Smets K, Van Hoecke H, De Leenheer E, Boudewyns A, Desloovere C, Kuhweide R, Muylle M, Royackers L, Schatteman I, Dhooge I. Hearing in Children with Congenital Cytomegalovirus Infection: Results of a Longitudinal Study. The Journal of Pediatrics. 2016;172:110-115.e2.  https://doi.org/10.1016/j.jpeds.2016.01.024
  18. Riga M, Korres G, Chouridis P, Naxakis S, Danielides V. Congenital cytomegalovirus infection inducing non-congenital sensorineural hearing loss during childhood; a systematic review. International Journal of Pediatric Otorhinolaryngology. 2018;115:156-164.  https://doi.org/10.1016/j.ijporl.2018.10.005
  19. Dobbie AM. Evaluation and management of cytomegalovirus-associated congenital hearing loss. Current Opinion in Otolaryngology and Head and Neck Surgery. 2017;25(5):390-395.  https://doi.org/10.1097/MOO.0000000000000401
  20. Gurov AV, Levina YuV, Rudenko VV. Sensorineural hearing impairment in combination with mycoplasma infection. Vestnik otorinolaringologii. 2015;80(1):9-11. (In Russ.). https://doi.org/10.17116/otorino20158019-11
  21. Mateer EJ, Huang C, Shehu NY, Paessler S. Lassa fever-induced sensorineural hearing loss: A neglected public health and social burden. PLoS Neglected Tropical Diseases. 2018;12(2):e0006187. https://doi.org/10.1371/journal.pntd.0006187
  22. Parrino D, Brescia G, Trimarchi MV, Tealdo G, Sasset L, Cattelan AM, Bovo R, Marioni G. Cochlear-Vestibular Impairment due to West Nile Virus Infection. The Annals of Otology, Rhinology, and Laryngology. 2019;128(12):1198-1202. https://doi.org/10.1177/0003489419866219
  23. Ribeiro BN, Guimarães AC, Yazawa F, Takara TF, de Carvalho GM, Zappelini CE. Sensorineural hearing loss in hemorrhagic dengue? International Journal of Surgery Case Reports. 2015;8C:38-41.  https://doi.org/10.1016/j.ijscr.2014.10.057
  24. Ensink RJH, Kuper H. Is hearing impairment associated with HIV? A systematic review of data from low- and middle-income countries. Tropical Medicine and International Health: TM & IH. 2017;22(12):1493-1504. https://doi.org/10.1111/tmi.12993
  25. Olbrich KJ, Müller D, Schumacher S, Beck E, Meszaros K, Koerber F. Systematic Review of Invasive Meningococcal Disease: Sequelae and Quality of Life Impact on Patients and Their Caregivers. Infectious Diseases and Therapy. 2018;7(4):421-438.  https://doi.org/10.1007/s40121-018-0213-2
  26. Curhan SG, Stankovic KM, Eavey RD, Wang M, Stampfer MJ, Curhan GC. Carotenoids, vitamin A, vitamin C, vitamin E, and folate and risk of self-reported hearing loss in women. The American Journal of Clinical Nutrition. 2015;102(5):1167-1175. https://doi.org/10.3945/ajcn.115.109314
  27. Emmett SD, West KP Jr. Gestational vitamin A deficiency: A novel cause of sensorineural hearing loss in the developing world? Medical Hypotheses. 2014;82(1):6-10.  https://doi.org/10.1016/j.mehy.2013.09.028
  28. Ghazavi H, Kargoshaie AA, Jamshidi-Koohsari M. Investigation of vitamin D levels in patients with Sudden Sensory-Neural Hearing Loss and its effect on treatment. American Journal of Otolaryngology. 2020;41(2):102327. https://doi.org/10.1016/j.amjoto.2019.102327
  29. Martínez-Vega R, Garrido F, Partearroyo T, Cediel R, Zeisel SH, Martínez-Álvarez C, Varela-Moreiras G, Varela-Nieto I, Pajares MA. Folic acid deficiency induces premature hearing loss through mechanisms involving cochlear oxidative stress and impairment of homocysteine metabolism. FASEB Journal. 2015; 29(2):418-432.  https://doi.org/10.1096/fj.14-259283
  30. Choudhury V, Amin SB, Agarwal A, Srivastava LM, Soni A, Saluja S. Latent iron deficiency at birth influences auditory neural maturation in late preterm and term infants. The American Journal of Clinical Nutrition. 2015;102(5):1030-1034. https://doi.org/10.3945/ajcn.115.113084
  31. Przewoźny T, Gójska-Grymajło A, Kwarciany M, Gąsecki D, Narkiewicz K. Hypertension and cochlear hearing loss. Blood Pressure. 2015;24(4):199-205.  https://doi.org/10.3109/08037051.2015.1049466
  32. Honeth L, Ström P, Ploner A, Bagger-Sjöbäck D, Rosenhall U, Nyrén O. Shooting history and presence of high-frequency hearing impairment in swedish hunters: A cross-sectional internet-based observational study. Noise and Health. 2015;17(78):273-281.  https://doi.org/10.4103/1463-1741.165043
  33. Gimsing S. The type of traumatic sensorineural hearing loss affects diagnostic and medico-legal assessment. Ugeskrift for Laeger. 2017;179(12):V09160664.
  34. Shangkuan WC, Lin HC, Shih CP, Cheng CA, Fan HC, Chung CH, Lin FH, Tsao CH, Chien WC. Increased long-term risk of hearing loss in patients with traumatic brain injury: A nationwide population-based study. Laryngoscope. 2017;127(11):2627-2635. https://doi.org/10.1002/lary.26567
  35. Staton CA, Msilanga D, Kiwango G, Vissoci JR, de Andrade L, Lester R, Hocker M, Gerardo CJ, Mvungi M. A prospective registry evaluating the epidemiology and clinical care of traumatic brain injury patients presenting to a regional referral hospital in Moshi, Tanzania: challenges and the way forward. International Journal of Injury Control and Safety Promotion. 2017;24(1):69-77.  https://doi.org/10.1080/17457300.2015.1061562
  36. Egorov VI, Kozarenko AV. Diagnosis and treatment of combat ear injuries. Al’manakh klinicheskoj meditsiny. 2016;44(7):844-849. (In Russ.). https://doi.org/10.18786/2072-0505-2016-44-7-841-849
  37. Churkin DV, Lastkov DO, Antropova OS. Assessment of the severity of hearing disorders in participants of a local military conflict with previous work experience in the conditions of industrial noise. Meditsina v Kuzbasse. 2018;17(2):9-14. 
  38. Irgens-Hansen K, Baste V, Bråtveit M, Lind O, Koefoed VF, Moen BE. Hearing loss in the Royal Norwegian Navy: A longitudinal study. Noise and Health. 2016;18(82):157-165.  https://doi.org/10.4103/1463-1741.181999
  39. Win KN, Balalla NB, Lwin MZ, Lai A. Noise-Induced Hearing Loss in the Police Force. Safety and Health at Work. 2015;6(2): 134-138.  https://doi.org/10.1016/j.shaw.2015.01.002
  40. Cruickshanks KJ, Nondahl DM, Dalton DS, Fischer ME, Klein BE, Klein R, Nieto FJ, Schubert CR, Tweed TS. Smoking, central adiposity, and poor glycemic control increase risk of hearing impairment. Journal of the American Geriatrics Society. 2015;63(5):918-924.  https://doi.org/10.1111/jgs.13401
  41. Mancini P, Atturo F, Di Mario A, Portanova G, Ralli M, De Virgilio A, de Vincentiis M, Greco A. Hearing loss in autoimmune disorders: Prevalence and therapeutic options. Autoimmunity Reviews. 2018;17(7):644-652.  https://doi.org/10.1016/j.autrev.2018.01.014
  42. Béquignon E, Guellich A, Bartier S, Raynal M, Prulière-Escabasse V, Canouï-Poitrine F, Coste A, Damy T. How your ears can tell what is hidden in your heart: wild-type transthyretin amyloidosis as potential cause of sensorineural hearing loss inelderly-AmyloDEAFNESS pilot study. Amyloid. 2017;24(2):96-100.  https://doi.org/10.1080/13506129.2017.1330744
  43. Okayasu T, Faquin WC, Nadol JB Jr. Sensorineural Hearing Loss in Leukemia: A Case Report Showing Intravascular Coagulation in the Cochlea and Vestibular Labyrinth. The Annals of Otology, Rhinology, and Laryngology. 2019;128(8):689-695.  https://doi.org/10.1177/0003489419838288
  44. Mohammed SH, Shab-Bidar S, Abuzerr S, Habtewold TD, Alizadeh S, Djafarian K. Association of anemia with sensorineural hearing loss: a systematic review and meta-analysis. BMC Research Notes. 2019;12(1):283.  https://doi.org/10.1186/s13104-019-4323-z
  45. Haremza C, Klopp-Dutote N, Strunski V, Page C. Evaluation of cardiovascular risks and recovery of idiopathic sudden sensorineural hearing loss in hospitalised patients: comparison between complete and partial sudden sensorineural hearing loss. The Journal of Laryngology and Otology. 2017;131(10):919-924.  https://doi.org/10.1017/S0022215117001736
  46. Przewoźny T, Gójska-Grymajło A, Kwarciany M, Graff B, Szmuda T, Gąsecki D, Narkiewicz K. Hypertension is associated with dysfunction of both peripheral and central auditory system. Journal of Hypertension. 2016;34(4):736-744.  https://doi.org/10.1097/HJH.0000000000000803
  47. Yikawe SS, Iseh KR, Sabir AA, Inoh MI, Solomon JH, Aliyu N. Cardiovascular risk factors and hearing loss among adults in a tertiary center of Northwestern Nigeria. World Journal of Otorhinolaryngology — Head and Neck Surgery. 2017;4(4):253-257.  https://doi.org/10.1016/j.wjorl.2017.05.015
  48. Evdokimova AG, Yunko SA, Gunchikov MV. Arterial hypertension and sensorineural hearing loss: relevance of the problem and features of treatment (focus on olmersartan). Medical Council. 2015;2:46-51. (In Russ.).
  49. Menezes AS, Ribeiro D, Lima A, Miranda D, Guimarães J, Dias L. SCORE risk scale as a prognostic factor after sudden sensorineural hearing loss. European Archives of Oto-Rhino-Laryngology. 2019;276(10):2739-2745. https://doi.org/10.1007/s00405-019-05518-1
  50. Chroni M, Prappa E, Kokkevi I. Bilateral sudden sensorineural hearing loss as a first symptom of infective endocarditis: two case reports. The Journal of Laryngology and Otology. 2018; 132(4):368-371.  https://doi.org/10.1017/S0022215118000269
  51. Besser J, Stropahl M, Urry E, Launer S. Comorbidities of hearing loss and the implications of multimorbidity for audiological care. Hearing Research. 2018;369:3-14.  https://doi.org/10.1016/j.heares.2018.06.008
  52. Croll PH, Bos D, Vernooij MW, Arshi B, Lin FR, Baatenburg de Jong RJ, Ikram MA, Goedegebure A, Kavousi M. Carotid Atherosclerosis Is Associated With Poorer Hearing in Older Adults. Journal of the American Medical Directors Association. 2019;20(12):1617-1622.e1.  https://doi.org/10.1016/j.jamda.2019.06.022
  53. Muus JS, Weir FW, Kreicher KL, Bowlby DA, Discolo CM, Meyer TA. Hearing loss in children with growth hormone deficiency. International Journal of Pediatric Otorhinolaryngology. 2017;100:107-113.  https://doi.org/10.1016/j.ijporl.2017.06.037
  54. Zhou Y, Qiu S, Liu D. Impact of metabolic syndrome on recovery of idiopathic sudden sensorineural hearing loss. American Journal of Otolaryngology. 2019;40(4):573-576.  https://doi.org/10.1016/j.amjoto.2019.05.011
  55. Ren H, Wang Z, Mao Z, Zhang P, Wang C, Liu A, Yuan G. Hearing Loss in Type 2 Diabetes in Association with Diabetic Neuropathy. Archives of Medical Research. 2017;48(7):631-637.  https://doi.org/10.1016/j.arcmed.2018.02.001
  56. Halliday E, Tan N. Sensorineural hearing loss and acute vestibulopathy in HELLP syndrome: A case report. Otolaryngology Case Reports. 2017;2(C):7-9.  https://doi.org/10.1016/j.xocr.2017.01.002
  57. Wang D, Zhou Y, Ma J, Xiao L, Cao L, Zhou M, Kong W, Wang Z, Li W, He M, Zhang X, Guo H, Yuan J, Chen W. Association between shift work and hearing loss: The Dongfeng-Tongji cohort study. Hearing Research. 2019;384:107827. https://doi.org/10.1016/j.heares.2019.107827
  58. Weier MH. The Association between Occupational Exposure to Hand-Arm Vibration and Hearing Loss: A Systematic Literature Review, Safety and Health at Work. 2020;11(3):249-261.  https://doi.org/10.1016/j.shaw.2020.04.003
  59. WHO. Global Health Risks: Mortality and Burden of Disease Attributable to Selected Major Risks. 2015. Accessed December 09, 2021. https://www.who.int/ru
  60. Babisch W, Beule B, Schust M, Kersten N, Ising H. Traffic Noise and Risk of Myocardial Infarction. Epidemiology. 2005;16(1):33-40.  https://doi.org/10.1097/01.ede.0000147104.84424.24
  61. Izmerov NF, Piktushanskaya TE. Mortality rates of patients with occupational diseases and assessment of the quality of medical care. Meditsina truda i promishlennaya ekologiya. 2016;9:18-23. (In Russ.).
  62. Babanov SA, Baraeva RA Occupational diseases of the cardiovascular system. RMZh. 2015;23(15):900. (In Russ.).
  63. Pankova VB. The importance of the quantitative assessment of the hearing impairment in the subjects employed under conditions of enhanced noise. Vestnik otorinolaringologii. 2018;83(3):33-36. (In Russ.). https://doi.org/10.17116/otorino201883333
  64. Castellanos MJ, Fuente A. The Adverse Effects of Heavy Metals with and without Noise Exposure on the Human Peripheral and Central Auditory System: A Literature Review. International Journal of Environmental Research and Public Health. 2016;13(12):1223. https://doi.org/10.3390/ijerph13121223
  65. Ostroumova OD, Chikh EV, Rebrova EV, Ryazanova AYu, Pereverzev AP. Drug-induced hearing loss as a manifestation of drug-induced ototoxicity. Vestnik otorinolaringologii. 2019;84(4):72‐80. (In Russ.). https://doi.org/10.17116/otorino20198404172
  66. Kryukov AI, Kunel’skaya NL, Abramov VYu, Temnov AA, Levina YuV, Kudeeva YaYu, Baibakova EV, Chugunova MA. The ototoxic action of cisplatin on the middle ear. Vestnik otorinolaringologii. 2015;80(1):21‐24. (In Russ.). https://doi.org/10.17116/otorino201580121-24
  67. He ZH, Li M, Zou SY, Liao FL, Ding YY, Su HG, Wei XF, Wei CJ, Mu YR, Kong WJ. Protection and Prevention of Age-Related Hearing Loss. Advances in Experimental Medicine and Biology. 2019;1130:59-71.  https://doi.org/10.1007/978-981-13-6123-4_4
  68. Ciorba A, Guidi MP, Skarżyński PH, Bianchini C, Rosignoli M, Mazzoli M, Pelucchi S, Hatzopoulos S. Rehabilitation of Severe to Profound Sensorineural Hearing Loss in Adults: Audiological Outcomes. Ear, Nose, and Throat Journal. 2021;100(3 Suppl):215-219.  https://doi.org/10.1177/0145561319892461
  69. Jafari Z, Kolb BE, Mohajerani MH. Age-related hearing loss and tinnitus, dementia risk, and auditory amplification outcomes. Ageing Research Reviews. 2019;56:100963. https://doi.org/10.1016/j.arr.2019.100963
  70. Patel R, McKinnon BJ. Hearing Loss in the Elderly. Clinics in Geriatric Medicine. 2018;34(2):163-174.  https://doi.org/10.1016/j.cger.2018.01.001
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