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Mashkova T.A.

Kafedra otorinolaringologii Voronezhskoĭ gosudarstvennoĭ meditsinskoĭ akademii im. N.N. Burdenko MZ RF

Mal'tsev A.B.

Kafedra otorinolaringologii Voronezhskoĭ gosudarstvennoĭ meditsinskoĭ akademii im. N.N. Burdenko

Nerovnyĭ A.I.

Kafedra otorinolaringologii Voronezhskoĭ gosudarstvennoĭ meditsinskoĭ akademii im. N.N. Burdenko MZ RF

Bakulina L.S.

N.N. Burdenko Voronezh State Medical University, Ministry of Health of the Russian Federation, Voronezh, Russia, 394036

The role of a leukotriene receptor antagonist in the restoration of the nasal breathing in the patients presenting with polypous rhinosinusitis

Authors:

Mashkova T.A., Mal'tsev A.B., Nerovnyĭ A.I., Bakulina L.S.

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Journal: Russian Bulletin of Otorhinolaryngology. 2017;82(5): 32‑35

DOI: 10.17116/otorino201782532-35

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THE ROLE OF A LEUKOTRIENE RECEPTOR ANTAGONIST IN THE RESTORATION OF THE NASAL BREATHING IN THE PATIENTS PRESENTING WITH POLYPOUS RHINOSINUSITIS
THE ROLE OF A LEUKOTRIENE RECEPTOR ANTAGONIST IN THE RESTORATION OF THE NASAL BREATHING IN THE PATIENTS PRESENTING WITH POLYPOUS RHINOSINUSITIS

To cite this article:

Mashkova TA, Mal'tsev AB, Nerovnyĭ AI, Bakulina LS. The role of a leukotriene receptor antagonist in the restoration of the nasal breathing in the patients presenting with polypous rhinosinusitis. Russian Bulletin of Otorhinolaryngology. 2017;82(5):32‑35. (In Russ.)
https://doi.org/10.17116/otorino201782532-35

Подписка 2025-2 (Russian Bulletin of Otorhinolaryngology)
 
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The present study was designed to investigate the clinical. laboratory, and morphological characteristics of the nasal obstruction process. It included 87 patients presenting with polypous rhinosinusitis. The dynamics of the serum leukotriene C4 (LTC4) level in the patients and the morphological changes in their polypous tissue suggested the existence of the pronounced exudative phase of allergic inflammation and provided a basis for the use of the leukotriene receptor antagonist in the form of the sodium montelucast tablets for the treatment of nasal obstruction.

Keywords:

polypous rhinosinusitis
nasal obstruction
allergic inflammation
hypoxia
leukotriene C4 (LTC4)
leukotriene receptor antagonist
sodium montelucast

Authors:

Mashkova T.A.

Kafedra otorinolaringologii Voronezhskoĭ gosudarstvennoĭ meditsinskoĭ akademii im. N.N. Burdenko MZ RF

Mal'tsev A.B.

Kafedra otorinolaringologii Voronezhskoĭ gosudarstvennoĭ meditsinskoĭ akademii im. N.N. Burdenko

Nerovnyĭ A.I.

Kafedra otorinolaringologii Voronezhskoĭ gosudarstvennoĭ meditsinskoĭ akademii im. N.N. Burdenko MZ RF

Bakulina L.S.

N.N. Burdenko Voronezh State Medical University, Ministry of Health of the Russian Federation, Voronezh, Russia, 394036

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