Mineral dysmetabolism in corneal diseases

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Functional status and biological properties of connective tissues significantly depend on the mineral elements involved in their metabolism. Connective tissue portion of the corneal stroma makes up most of its thickness; pathological changes in collagen fibers and the stroma can cause a range of corneal diseases, some of which are specifically associated with disorders of mineral metabolism. The article considers impairments of mineral metabolism as possible pathophysiological mechanisms in certain diseases and disorders of the cornea, and describes in detail the abnormalities associated with mineral dysmetabolism observed in patients with keratoconus.

Keywords:

keratoconus

Fleischer ring

zinc

copper

iron

Authors:

Pateyuk L.S.

Krasnov Research Institute of Eye Diseases

ORCID: 0000-0002-5757-6719

Subbot A.M.

M.M. Krasnov Research Institute of Eye Diseases

ORCID: 0000-0002-8258-6011

Kobzeva A.V.

Krasnov Research Institute of Eye Diseases

ORCID: 0000-0002-0771-8934

Received:

21.03.2022

Accepted:

12.04.2022

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