Comparative evaluation of hypotensive effectiveness of topical monotherapy and selective laser trabeculectomy

Erichev V.P.; Poleva R.P.; Ragozina E.A.; Kozlova I.V.

doi:https://doi.org/10.17116/oftalma2022138052215

Erichev V.P.

Krasnov Research Institute of Eye Diseases

ORCID: 0000-0001-6842-7164

Poleva R.P.

Krasnov Research Institute of Eye Diseases

ORCID: 0000-0003-3421-1298

Ragozina E.A.

Research Institute of Eye Diseases

Kozlova I.V.

Krasnov Research Institute of Eye Diseases

ORCID: 0000-0003-3885-9649

Comparative evaluation of hypotensive effectiveness of topical monotherapy and selective laser trabeculectomy

Authors:

Erichev V.P., Poleva R.P., Ragozina E.A., Kozlova I.V.

More about the authors

Journal: Russian Annals of Ophthalmology. 2022;138(5‑2): 215‑220

DOI: 10.17116/oftalma2022138052215

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To cite this article:

Erichev VP, Poleva RP, Ragozina EA, Kozlova IV. Comparative evaluation of hypotensive effectiveness of topical monotherapy and selective laser trabeculectomy. Russian Annals of Ophthalmology. 2022;138(5‑2):215‑220. (In Russ.)
https://doi.org/10.17116/oftalma2022138052215

Подписка 2026 Вестник офтальмологии (Russian Annals of Ophthalmology)

Использование инфографики авторами научных работ

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PURPOSE

Comparison of the hypotensive effects of selective laser trabeculoplasty (SLT) and drug therapy in patients with newly diagnosed primary open-angle glaucoma (POAG) and ocular hypertension.

MATERIAL AND METHODS

Thirty patients (30 eyes) with newly diagnosed ophthalmic hypertension or POAG were observed. Patients of the 1st group (15 eyes) underwent standard SLT as a starting treatment, patients of the 2nd group (15 eyes) were prescribed monotherapy with a prostaglandin analog. Corneal compensated intraocular pressure (IOPcc) was measured for each patient using Ocular Response Analyzer («Reichert Technologies», USA). The observation period lasted 6 months.

RESULTS

During the 6-months follow-up, tafluprost was found to effectively reduce IOP in 93.3% of cases, SLT — in 73.3% of cases. There were no statistically significant differences in hypotensive effectiveness between the two compared treatments, which amounted to 27.9—28.5% reduction from the baseline values.

CONCLUSION

Selective laser trabeculectomy and topical drug therapy have shown similar hypotensive effectiveness during the 6-months follow-up when used as the initial therapy for POAG.

Keywords:

selective laser trabeculoplasty

ocular hypertension

primary open-angle glaucoma

intraocular pressure

Authors:

Erichev V.P.

Krasnov Research Institute of Eye Diseases

ORCID: 0000-0001-6842-7164

Poleva R.P.

Krasnov Research Institute of Eye Diseases

ORCID: 0000-0003-3421-1298

Ragozina E.A.

Research Institute of Eye Diseases

Kozlova I.V.

Krasnov Research Institute of Eye Diseases

ORCID: 0000-0003-3885-9649

Received:

12.04.2022

Accepted:

16.06.2022

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