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Grusha Y.O.

I.M. Sechenov First Moscow State Medical University (Sechenov University);
Krasnov Research Institute of Eye Diseases

Fettser E.I.

Krasnov Research Institute of Eye Diseases;
Sechenov First Moscow State Medical University

Fedorov A.A.

Moscow Regional Scientific Research Institute of Obstetrics and Gynecology

Ismailova D.S.

Research Institute of Eye Diseases

Nonspecific inflammatory reaction after implantation of palpebral implants

Authors:

Grusha Y.O., Fettser E.I., Fedorov A.A., Ismailova D.S.

More about the authors

Journal: Russian Annals of Ophthalmology. 2022;138(1): 38‑43

DOI: 10.17116/oftalma202213801138

Read: 1222 times

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Table of contents

NONSPECIFIC INFLAMMATORY REACTION AFTER IMPLANTATION OF PALPEBRAL IMPLANTS
NONSPECIFIC INFLAMMATORY REACTION AFTER IMPLANTATION OF PALPEBRAL IMPLANTS

To cite this article:

Grusha YO, Fettser EI, Fedorov AA, Ismailova DS. Nonspecific inflammatory reaction after implantation of palpebral implants. Russian Annals of Ophthalmology. 2022;138(1):38‑43. (In Russ.)
https://doi.org/10.17116/oftalma202213801138

Подписка 2026 Вестник офтальмологии (Russian Annals of Ophthalmology)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

PURPOSE

To identify the possible cause of an inflammatory reaction to a Russian-manufactured palpebral implant made of gold in the long term after surgery, and to determine the clinical and morphological changes in the tissues of the upper eyelid when the presence of the implant caused the inflammatory reaction.

MATERIAL AND METHODS

The results of 150 operations with placement of a palpebral implant were analyzed. In 12 cases, a nonspecific inflammatory reaction was revealed within 2 to 4 weeks after the operation, in 7 cases it necessitated explantation, in 5 cases the local long-term use of an ointment with a corticosteroid made it possible to avoid extrusion and explantation. Chemical microanalysis of the palpebral implant and fragments of the removed capsule was performed using scanning electron microscopy (SEM), as well as immunohistochemical (IHC), macro- and microscopic examination of the fragments of connective tissue capsule was carried out after removal of the palpebral implant.

RESULTS

The obtained data confirm the chemical purity of the implant, the absence of abnormal accumulation of metals in the tissues of the eyelid. IHC, macro- and microscopic examination of the presented fragments of the connective tissue capsule revealed signs characteristic of an inflammatory reaction to a foreign body.

CONCLUSION

Further research is needed to establish the factors and predictors for the development of inflammatory reactions to a foreign body and, in particular, to gold.

Keywords:

gold
eyelid implant
lagophthalmos
facial paralysis
noninfectious inflammatory
type IV hypersensitivity
platinum

Authors:

Grusha Y.O.

I.M. Sechenov First Moscow State Medical University (Sechenov University);
Krasnov Research Institute of Eye Diseases

Fettser E.I.

Krasnov Research Institute of Eye Diseases;
Sechenov First Moscow State Medical University

Fedorov A.A.

Moscow Regional Scientific Research Institute of Obstetrics and Gynecology

Ismailova D.S.

Research Institute of Eye Diseases

Received:

19.04.2021

Accepted:

12.06.2021

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