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Kondratieva T.B.
I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia, Moscow, Russia
Popova L.V.
I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia, Moscow, Russia
Bokarev I.N.
kafedra gospital'noĭ terapii Moskovskoĭ meditsinskoĭ akademii im. I.M. Sechenova
Non-vitamin K antagonist oral anticoagulants for heart diseases
Journal: Therapeutic Archive. 2017;89(9): 120‑127
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To cite this article:
Kondratieva TB, Popova LV, Bokarev IN. Non-vitamin K antagonist oral anticoagulants for heart diseases. Therapeutic Archive.
2017;89(9):120‑127. (In Russ.)
https://doi.org/10.17116/terarkh2017899120-127
Non-vitamin K antagonist oral anticoagulants (NОАСs) are highly effective drugs that prevent venous thrombosis and stroke in atrial fibrillation. Their use has difficulties that are associated with the need for laboratory control and with the influence of many factors on the activity of these medications. The emerged direct oral anticoagulants have some advantages over NOACs. Nevertheless, there are a number of pathological conditions, in which NOACs remain first-line drugs. These include prosthetic mechanical heart valves, a glomerular filtration rate less than 60 mL/min/1.73 m2, and left atrial thrombus.
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Authors:
Kondratieva T.B.
I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia, Moscow, Russia
Popova L.V.
I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia, Moscow, Russia
Bokarev I.N.
kafedra gospital'noĭ terapii Moskovskoĭ meditsinskoĭ akademii im. I.M. Sechenova
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