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Galstyan G.M.

National Research Center for Hematology, Moscow, Russia

Polevodova O.A.

National Research Center for Hematology, Moscow, Russia

Gavrish A.Yu.

National Research Center for Hematology, Ministry of Health of Russia, Moscow, Russia

Polianskaia T.Iu.

Gematologicheskiĭ nauchnyĭ tsentr Minzdrava RF, Moskva

Zorenko V.Yu.

Gematologicheskiĭ nauchnyĭ tsentr Minzdrava RF, Moskva

Sampiev M.S.

National Research Center for Hematology, Ministry of Health of Russia, Moscow, Russia

Biriukova L.S.

Gematologicheskiĭ nauchnyĭ tsentr Ministerstva zdravookhraneniia Rossii

Model S.V.

National Research Center for Hematology, Ministry of Health of Russia, Moscow, Russia

Gorgidze L.A.

National Research Center for Hematology, Ministry of Health of Russia, Moscow, Russia

Savchenko V.G.

National Research Center for Hematology, Moscow, Russia

Thrombotic events in patients with hemophilia

Authors:

Galstyan G.M., Polevodova O.A., Gavrish A.Yu., Polianskaia T.Iu., Zorenko V.Yu., Sampiev M.S., Biriukova L.S., Model S.V., Gorgidze L.A., Savchenko V.G.

More about the authors

Journal: Therapeutic Archive. 2017;89(7): 76‑84

DOI: 10.17116/terarkh201789776-84

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Table of contents

THROMBOTIC EVENTS IN PATIENTS WITH HEMOPHILIA
THROMBOTIC EVENTS IN PATIENTS WITH HEMOPHILIA

To cite this article:

Galstyan GM, Polevodova OA, Gavrish AYu, et al. . Thrombotic events in patients with hemophilia. Therapeutic Archive. 2017;89(7):76‑84. (In Russ.)
https://doi.org/10.17116/terarkh201789776-84

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Abstract:

The paper describes 4 clinical cases of thrombotic events (pulmonary embolism, deep vein thrombophlebitis, acute myocardial infarction, ischemic stroke) that have occurred in patients with hemophilia. It discusses the possible causes of their development and methods for their prevention and treatment. Controlled natural hypocoagulation, in which the dose of an administered deficient factor decreases to such an extent that in order to maintain the safe level of hypocoagulation (plasma factor activity is 15—20%; activated partial thromboplastin time is 1.5—2 times normal values), is proposed as one of the treatment options.

Keywords:

hemophilia
coagulation factor VIII
coagulation factor IX
deep vein thrombosis
ischemic stroke
pulmonary embolism
myocardial infarction
thrombophilia
hypocoagulation
thromboelastography

Authors:

Galstyan G.M.

National Research Center for Hematology, Moscow, Russia

Polevodova O.A.

National Research Center for Hematology, Moscow, Russia

Gavrish A.Yu.

National Research Center for Hematology, Ministry of Health of Russia, Moscow, Russia

Polianskaia T.Iu.

Gematologicheskiĭ nauchnyĭ tsentr Minzdrava RF, Moskva

Zorenko V.Yu.

Gematologicheskiĭ nauchnyĭ tsentr Minzdrava RF, Moskva

Sampiev M.S.

National Research Center for Hematology, Ministry of Health of Russia, Moscow, Russia

Biriukova L.S.

Gematologicheskiĭ nauchnyĭ tsentr Ministerstva zdravookhraneniia Rossii

Model S.V.

National Research Center for Hematology, Ministry of Health of Russia, Moscow, Russia

Gorgidze L.A.

National Research Center for Hematology, Ministry of Health of Russia, Moscow, Russia

Savchenko V.G.

National Research Center for Hematology, Moscow, Russia

Close metadata

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