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El'kin V.D.

E.A. Vagner Perm State Medical Academy

Sedova T.G.

State Educational Institution of Additional Professional Education «E.A. Vagner Perm State Medical Academy»

Kopytova E.A.

GBOU VPO «Permskij gosudarstvennyj meditsinskij universitet im. akad. E.A. Vagnera» Minzdrava Rossii, Perm', Rossija, 614099

Plotnikova E.V.

E.A. Vagner Perm State Medical Academy

Langerhans cell histiocytosis: Skin diseases and visceral lesions

Authors:

El'kin V.D., Sedova T.G., Kopytova E.A., Plotnikova E.V.

More about the authors

Journal: Therapeutic Archive. 2017;89(4): 115‑120

DOI: 10.17116/terarkh2017894115-120

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Table of contents

LANGERHANS CELL HISTIOCYTOSIS: SKIN DISEASES AND VISCERAL LESIONS
LANGERHANS CELL HISTIOCYTOSIS: SKIN DISEASES AND VISCERAL LESIONS

To cite this article:

El'kin VD, Sedova TG, Kopytova EA, Plotnikova EV. Langerhans cell histiocytosis: Skin diseases and visceral lesions. Therapeutic Archive. 2017;89(4):115‑120. (In Russ.)
https://doi.org/10.17116/terarkh2017894115-120

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Abstract:

Langerhans cell histiocytosis (LCH) is a rare clonal proliferative disorder that belongs to class I histiocytoses and is characterized by infiltration of one or many organs by Langerhans cells to form granulomas. The literature analysis could identify a lot of etiological, pathogenetic, and trigger factors and mechanisms for LCH development, which determine the diversity of the clinical picture and course of the disease. The clinical manifestations of LCH are very variable and depend on the severity of lesions and the age of patients. In addition to skin lesions, there is involvement of one or more visceral organs. Difficulties in diagnosing the disease lead to statistical variations of LCH in different countries of the world and require more attention by physicians of all specialties.

Keywords:

Langerhans cell histiocytosis
clinical picture
diagnosis
treatment
prognosis

Authors:

El'kin V.D.

E.A. Vagner Perm State Medical Academy

Sedova T.G.

State Educational Institution of Additional Professional Education «E.A. Vagner Perm State Medical Academy»

Kopytova E.A.

GBOU VPO «Permskij gosudarstvennyj meditsinskij universitet im. akad. E.A. Vagnera» Minzdrava Rossii, Perm', Rossija, 614099

Plotnikova E.V.

E.A. Vagner Perm State Medical Academy

Close metadata

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