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Malyshev M.E.

Institute of Emergency Care. Y.Y. Dzhanelidze, Saint-Petersburg, Russia

Iordanishvili A.K.

North-Western State Medical University of I.I. Mechnikov, St. Petersburg;
S.M. Kirov′s Military Medical Academy, St. Petersburg

Prisyazhnyuk O.V.

Dental Clinic №29 of the Frunzensky district, Saint-Petersburg, Russia

Bumai A.O.

St. Petersburg University, St. Petersburg, Russia;
St. Petersburg I.I. Dzhanelidze Research Institute of Emergency Medicine, St. Petersburg, Russia

The effect of probiotics on the secretory immunity of saliva in patients with type 2 diabetes

Authors:

Malyshev M.E., Iordanishvili A.K., Prisyazhnyuk O.V., Bumai A.O.

More about the authors

Journal: Stomatology. 2019;98(6): 26‑29

DOI: 10.17116/stomat20199806126

Read: 1300 times

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Table of contents

THE EFFECT OF PROBIOTICS ON THE SECRETORY IMMUNITY OF SALIVA IN PATIENTS WITH TYPE 2 DIABETES
THE EFFECT OF PROBIOTICS ON THE SECRETORY IMMUNITY OF SALIVA IN PATIENTS WITH TYPE 2 DIABETES

To cite this article:

Malyshev ME, Iordanishvili AK, Prisyazhnyuk OV, Bumai AO. The effect of probiotics on the secretory immunity of saliva in patients with type 2 diabetes. Stomatology. 2019;98(6):26‑29. (In Russ.)
https://doi.org/10.17116/stomat20199806126

Подписка 2026 Стоматология (Stomatology)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

The aim of the study was to study the effect of the use of probiotics on the state of mucosal immunity in patients with type 2 diabetes. Evaluation of the results was carried out based on immunological parameters of the saliva of 50 patients suffering from type 2 diabetes with moderate periodontitis, before and 1 month after taking a probiotic complex based on Lactobacillus. In the salivary fluid of patients, a decrease in the concentration of pro-inflammatory cytokines IL-1β, TNF-α and IL-8 was noted, while an increase in the anti-inflammatory cytokine IL-10 was observed. An increase in local mucosal immunity was also observed, manifested in an increase in the synthesis of secretory immunoglobulin A.

Keywords:

periodontitis
diabetes mellitus
secretory immunity
probiotics

Authors:

Malyshev M.E.

Institute of Emergency Care. Y.Y. Dzhanelidze, Saint-Petersburg, Russia

Iordanishvili A.K.

North-Western State Medical University of I.I. Mechnikov, St. Petersburg;
S.M. Kirov′s Military Medical Academy, St. Petersburg

Prisyazhnyuk O.V.

Dental Clinic №29 of the Frunzensky district, Saint-Petersburg, Russia

Bumai A.O.

St. Petersburg University, St. Petersburg, Russia;
St. Petersburg I.I. Dzhanelidze Research Institute of Emergency Medicine, St. Petersburg, Russia

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References:

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