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Ivaniushko T.P.

Kafedra GKhS i ChLKh PMGMU im. I.M. Sechenova;
ZAO "NPF DNK-Tekhnologiia", Moskva

Simonova A.V.

Meditsinskiĭ kholding "SM-Klinika"

Poliakov K.A.

Kunizheva M.A.

I.M. Sechenov First Moscow State Medical University Ministry of Health of Russia, Moscow, Russia

Diagnostic value of chromato-mass-spectrometry in patients with drug-induced jaws osteonecrosis

Authors:

Ivaniushko T.P., Simonova A.V., Poliakov K.A., Kunizheva M.A.

More about the authors

Journal: Stomatology. 2019;98(3): 42‑45

DOI: 10.17116/stomat20199803142

Read: 1501 times

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Table of contents

DIAGNOSTIC VALUE OF CHROMATO-MASS-SPECTROMETRY IN PATIENTS WITH DRUG-INDUCED JAWS OSTEONECROSIS
DIAGNOSTIC VALUE OF CHROMATO-MASS-SPECTROMETRY IN PATIENTS WITH DRUG-INDUCED JAWS OSTEONECROSIS

To cite this article:

Ivaniushko TP, Simonova AV, Poliakov KA, Kunizheva MA. Diagnostic value of chromato-mass-spectrometry in patients with drug-induced jaws osteonecrosis. Stomatology. 2019;98(3):42‑45. (In Russ.)
https://doi.org/10.17116/stomat20199803142

Подписка 2026 Стоматология (Stomatology)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

In patients with drag-induced jaw osteonecrosis which developed in cancer patients due to administration of bisphosphonates for metastases, the microflora of the oral cavity was examined by chromatography-mass spectrometry (HMS). The method of HMS can be used as an additional method of diagnostics in complex clinical cases with ineffective treatment.

Authors:

Ivaniushko T.P.

Kafedra GKhS i ChLKh PMGMU im. I.M. Sechenova;
ZAO "NPF DNK-Tekhnologiia", Moskva

Simonova A.V.

Meditsinskiĭ kholding "SM-Klinika"

Poliakov K.A.

Kunizheva M.A.

I.M. Sechenov First Moscow State Medical University Ministry of Health of Russia, Moscow, Russia

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References:

  1. Hesse B, Langer M, Varga P, Pacureanu A, Dong P, Schrof S, Männicke N, Suhonen H, Olivier C, Maurer P, Kazakia GJ, Raum K, Peyrin F. Alterations of mass density and 3D osteocyte lacunar properties in bisphosphonate-related osteonecrotic human jaw bone, a synchrotron µCT study. PLoS One. 2014;9(2):e88481. eCollection 2014. https://doi.org/10.1371/journal.pone.0088481
  2. Córdova LA, Guilbaud F, Amiaud J, Battaglia S, Charrier C, Lezot F, Piot B, Redini F, Heymann D. Severe compromise of preosteoblasts in a surgical mouse model of bisphosphonate-associated osteonecrosis of the jaw. J Craniomaxillofac Surg. 2016;44(9):1387-1394. https://doi.org/10.1016/j.jcms.2016.07.015
  3. Akita Y, Kuroshima S, Nakajima K, Hayano H, Kanai R, Sasaki M, Sawase T. Effect of anti-angiogenesis induced by chemotherapeutic monotherapy, chemotherapeutic/bisphosphonate combination therapy and anti-VEGFA mAb therapy on tooth extraction socket healing in mice. J Bone Miner Metab. 2017. https://doi.org/10.1007/s00774-017-0872-1
  4. García-de Marcos JA, Rey-Biel J. Submental perforator flap for soft-tissue reconstruction in bisphosphonate-related osteonecrosis of the jaws. Craniomaxillofac Trauma Reconstr. 2017;10(4):299-305. https://doi.org/10.1055/s-0036-1593472
  5. De Bruyn L, Coropciuc R, Coucke W, Politis C. Microbial population changes in patients with medication-related osteonecrosis of the jaw treated with systemic antibiotics. Oral Surg Oral Med Oral Pathol Oral Radiol. 2018;125(3):268-275. https://doi.org/10.1016/j.oooo.2017.11.022
  6. Ivanyushko TP, Polyakov KA, Medvedev YuA, Shamanaev SV, Trofimov DYu, Abramov DD, Balykin RA. Investigation of conditionally pathogenic microorganisms in patients with bisphosphonate osteonecrosis of the jaws. Stomatology. 2016;95:1:44-48. (In Russ.) https://doi.org/10.17116/stomat201695144-48
  7. Gupta S, Gupta H, Mandhyan D, Srivastava S. Bisphophonates related osteonecrosis of the jaw. Natl J Maxillofac Surg. 2013;4(2):151-158. https://doi.org/10.4103/0975-5950.127643
  8. Kuroshima S, Al-Salihi Z, Yamashita J. Mouse anti-RANKL antibody delays oral wound healing and increases TRAP-positive mononuclear cells in bone marrow. Clin Oral Investig. 2016;20(4):727-736. https://doi.org/10.1007/s00784-015-1550-0
  9. Patel V, Mansi J, Ghosh S, Kwok J, Burke M, Reilly D, Nizarali N, Sproat C, Chia K. MRONJ risk of adjuvant bisphosphonates in early stage breast cancer. Br Dent J. 2018;224(2):74-79. https://doi.org/10.1038/sj.bdj.2017.1039
  10. Kim DH, Lee JS, Pyo SW, Lee JH. Ascending facial necrotizing fasciitis in a patient taking a bisphosphonate. J Oral Maxillofac Surg. 2017;75(2):317-321. https://doi.org/10.1016/j.joms.2016.08.012
  11. Osipov GA, Fedosova NF, Lyadov KV. Quantitative in situ microbiological analysis of lipid markers in biological fluids using the gas chromatography-mass spectrometry method. Public Health and Medical Technologies. 2007;5:20-23. (In Russ.)
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