The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-0604
+8 800 250-18-12
  • (toll-free number for subscriptions)
    Mon-Fri from 10 a.m. to 6 p.m.

  • © 1998-2025
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Ginter O.V.

National Medical Research Center of Children’s Health, Moscow

Namazova-baranova L.S.

Scientific Centre of Children Health, Moscow, Russia

Mospan T.Ya.

National Medical Research Center of Children’s Health, Moscow

Jourkova N.V.

National Medical Research Center of Children’s Health, Moscow

Davydova I.V.

National Medical Research Center of Children’s Health, Moscow;
Russia

Pushkov A.A.

National Medical Research Center of Children’s Health, Moscow

Clinical case of congenital cleft palate in 22q11.2 deletion syndrome

Authors:

Ginter O.V., Namazova-baranova L.S., Mospan T.Ya., Jourkova N.V., Davydova I.V., Pushkov A.A.

More about the authors

Journal: Stomatology. 2019;98(1): 61‑63

DOI: 10.17116/stomat20199801161

Read: 2153 times

Download PDF (RU)
Contact the author
Table of contents

CLINICAL CASE OF CONGENITAL CLEFT PALATE IN 22Q11.2 DELETION SYNDROME
CLINICAL CASE OF CONGENITAL CLEFT PALATE IN 22Q11.2 DELETION SYNDROME

To cite this article:

Ginter OV, Namazova-baranova LS, Mospan TYa, Jourkova NV, Davydova IV, Pushkov AA. Clinical case of congenital cleft palate in 22q11.2 deletion syndrome. Stomatology. 2019;98(1):61‑63. (In Russ.)
https://doi.org/10.17116/stomat20199801161

Подписка 2026 Стоматология (Stomatology)
 
МСФ на ЯМ
Использование инфографики авторами научных работ
Close metadata
Abstract:

The paper presents a clinical case of congenital cleft palate as a manifestation of 22q11.2 deletion syndrome accompanied by other systemic disorders having direct impact on functional indicators and perioperative period during cleft surgery. Specific for 22q11.2 deletion syndrome endocrine disorders affect the facial development. Multidisciplinary approach contributes to the early optimal treatment outcome and prevents further postoperative disturbances in maxillofacial development.

Keywords:

congenital cleft palate
deletion 22q112
children
syndrome
chromosome
chromosomal disease

Authors:

Ginter O.V.

National Medical Research Center of Children’s Health, Moscow

Namazova-baranova L.S.

Scientific Centre of Children Health, Moscow, Russia

Mospan T.Ya.

National Medical Research Center of Children’s Health, Moscow

Jourkova N.V.

National Medical Research Center of Children’s Health, Moscow

Davydova I.V.

National Medical Research Center of Children’s Health, Moscow;
Russia

Pushkov A.A.

National Medical Research Center of Children’s Health, Moscow

Close metadata

References:

  1. Bassett AS, McDonald-McGinn DM, Devriendt K, et al. Practical guidelines for managing patients with 22q11.2 deletion syndrome. J Pediatr. 2011;159(2):332-339.e1. https://doi.org/10.1016/j.jpeds.2011.02.039
  2. Delio M, Guo T, McDonald-McGinn DM, et al. Enhanced maternal origin of the 22q11.2 deletion in velocardiofacial and DiGeorge syndromes. Am J Hum Genet. 2013;92(3):439-447. https://doi.org/10.1016/j.ajhg.2013.01.018
  3. Cheung EN, George SR, Costain GA, et al. Prevalence of hypocalcemia and its associated features in 22q11.2 deletion syndrome. Clin Endocrinol (Oxf). 2014;81(2):190-196. https://doi.org/10.1111/cen.12466
  4. Taylor SC, Morris G, Wilson D, et al. Hypoparathyroidism and 22q11 deletion syndrome. Arch Dis Child. 2003;88(6):520-522. https://doi.org/10.1136/adc.88.6.520
  5. Piliero LM, Sanford AN, McDonald-McGinn DM, et al. T-cell homeostasis in humans with thymic hypoplasia due to chromosome 22q11.2 deletion syndrome. Blood. 2004;103(3):1020-11025. https://doi.org/10.1182/blood-2003-08-2824
  6. Glaser B, Mumme DL, Blasey C, et al. Language skills in children with velocardiofacial syndrome (deletion 22q11.2). J Pediatr. 2002;140(6):753-758. https://doi.org/10.1067/mpd.2002.124774
  7. Gerdes M, Solot C, Wang PP, et al. Cognitive and behavior profile of preschool children with chromosome 22q11.2 deletion. Am J Med Genet. 1999;85(2):127-133. https://doi.org/10.1002/(sici)1096-8628(19990716)85:2<127::aid-ajmg6>3.3.co;2-6
  8. Scambler PJ. The 22q11 deletion syndrome. Hum Mol Genet. 2000;9(16):2421-2426. https://doi.org/10.1093/hmg/9.16.2421
  9. McElhinney DB, McDonald-McGinn D, Zackai EH, Goldmuntz E. Cardiovascular anomalies in patients diagnosed with a chromosome 22q11 deletion beyond 6 months of age. Pediatrics. 2001;108(6):e104. https://doi.org/10.1542/peds.108.6.e104
  10. Greenhalgh KL, Aligianis IA, Bromilow G, et al. 22q11 deletion: a multisystem disorder requiring multidisciplinary input. Arch Dis Child. 2003;88(6):523-524. https://doi.org/10.1136/adc.88.6.523
  11. Digilio MC, Pacifico C, Tieri L, et al. Audiological findings in patients with microdeletion 22q11 (di George/velocardiofacial syndrome). Br J Audiol. 1999;33(5):329-333. https://doi.org/10.3109/03005369909090116
  12. Ford LC, Sulprizio SL, Rasgon BM. Otolaryngological manifestations of velocardiofacial syndrome: a retrospective review of 35 patients. Laryngoscope. 2000;110(3 Pt 1):362-367. https://doi.org/10.1097/00005537-200003000-00006
  13. Zemble R, Luning Prak E, McDonald K, et al. Secondary immunologic consequences in chromosome 22q11.2 deletion syndrome (DiGeorge syndrome/velocardiofacial syndrome). Clin Immunol. 2010;136(3):409-418. https://doi.org/10.1016/j.clim.2010.04.011
  14. Green T, Gothelf D, Glaser B, et al. Psychiatric disorders and intellectual functioning throughout development in velocardiofacial (22q11.2 deletion) syndrome. J Am Acad Child Adolesc Psychiatry. 2009;48(11):1060-1068. https://doi.org/10.1097/CHI.0b013e3181b76683
Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Contact us
If you have any questions, complaints or suggestions, please use this feedback form.
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.
Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.