Clinical and morphological features of odontogenic keratocysts

Semkin V.A.

Otdelenie khirurgicheskoĭ stomatologii FGBU "Tsentral'nyĭ nauchno-issledovatel'skiĭ institut stomatologii i cheliustno-litsevoĭ khirurgii" Minzdrava RF, Moskva

Babichenko I.I.

Russian University of People’s Friendship, Moscow, Russia, 117198

Usachev E.S.

Otdelenie khirurgicheskoĭ stomatologii FGBU "Tsentral'nyĭ nauchno-issledovatel'skiĭ institut stomatologii i cheliustno-litsevoĭ khirurgii" Minzdrava RF, Moskva

Zaretskaia A.S.

Tsentral'nyĭ nauchno-issledovatel'skiĭ institut stomatologii i cheliustno-litsevoĭ khirurgii, Moskva

Clinical and morphological features of odontogenic keratocysts

Authors:

Semkin V.A., Babichenko I.I., Usachev E.S., Zaretskaia A.S.

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Journal: Stomatology. 2013;92(5): 14‑18

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To cite this article:

Semkin VA, Babichenko II, Usachev ES, Zaretskaia AS. Clinical and morphological features of odontogenic keratocysts. Stomatology. 2013;92(5):14‑18. (In Russ.)

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Clinical, histological and immunohystochemical studies of keratocystic tumors were performed showing differences in proliferative activity and MMP-9 expression scores in orthokeratinized and parakeratinised cysts. These histological features are associated with clinical course and may be used as markers for recurrence probability.

Keywords:

orthokeratinized odontogenic cyst (OOC)

keratocystic odontogenic tumor (KCOT)

matrix metalloproteinase-9 (MMP-9)

Ki-67

prognostic markers

surgical treatment

Authors:

Semkin V.A.

Otdelenie khirurgicheskoĭ stomatologii FGBU "Tsentral'nyĭ nauchno-issledovatel'skiĭ institut stomatologii i cheliustno-litsevoĭ khirurgii" Minzdrava RF, Moskva

Babichenko I.I.

Russian University of People’s Friendship, Moscow, Russia, 117198

Usachev E.S.

Otdelenie khirurgicheskoĭ stomatologii FGBU "Tsentral'nyĭ nauchno-issledovatel'skiĭ institut stomatologii i cheliustno-litsevoĭ khirurgii" Minzdrava RF, Moskva

Zaretskaia A.S.

Tsentral'nyĭ nauchno-issledovatel'skiĭ institut stomatologii i cheliustno-litsevoĭ khirurgii, Moskva

List of references:

Woolgar J.A., Rippin J.W., Browne R.M. A comparative study of the clinical and histological features of recurrent and nonrecurrent odontogenic keratocysts. J Oral Pathol 1987; 16: 124.
Zachariades N., Papanicolaou S., Triantafyllou D. Odontogenic keratocysts: Review of the literature and report of sixteen cases. J Oral Maxillofac Surg 1985; 43: 177.
Haring J.I., VanDis M.L. Odontogenic keratocysts: A clinical, radiographic, and histologic study. Oral Surg Oral Med Oral Pathol 1988; 66: 145.
Ahlfors E., Larsson A., Sjogren S. The odontogenic keratocyst: A benign cystic tumor? J Oral Maxillofac Surg 1984; 42: 10.
Brannon R.B. The odontogenic keratocyst: A clinicopathologic study of 312 cases. Part II. Histologic features. Oral Surg Oral Med Oral Pathol 1977; 43: 233.
Wright J.M. The odontogenic keratocyst: Orthokeratinized variant. Oral Surg Oral Med Oral Pathol 1981; 51: 609-618.
Philipsen H.P. In: L. Barnes, J.W. Eveson, P. Reichart, D. Sidransky. (eds) World Health Organization classification of tumours. Pathology and genetics of head and neck tumours. IARC, Lyon 2005; 306-307.
González-Alva P., Tanaka A., Oku Y., Yoshizawa D., Itoh S., Sakashita H., Ide F., Tajima Y., Kusama K. Keratocystic odontogenic tumor: a retrospective study of 183 cases. J Oral Sci 2008; 50: 2: 205-212.
Rangiani A., Motahhary P. Evaluation of bax and bcl-2 expression in odontogenic keratocysts and orthokeratinized odontogenic cysts: A comparison of two cysts. Oral Oncology 2009; 45: 41-44.
Mario James A. da Silva et al. Immunohistochemical study of the orthokeratinized odontogenic cyst: A somparison with the odontogenic keratocyst. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2002; 94: 732-737.
Slootweg P.J. Lesions of the jaws. Histopathology 2009; 54: 401-418.
Bhargava D., Deshpande A., Pogrel M.A. Keratocystic odontogenic tumour (KCOT) - a cyst to a tumour. Oral Maxillofac Surg 2012; 16: 2: 163-170.
Kuroyanagi N., Sakuma H., Miyabe S., Machida J., Kaetsu A., Yokoi M., Maeda H., Warnakulasuriya S., Nagao T., Shimozato K. Prognostic factors for keratocystic odontogenic tumor (odontogenic keratocyst): analysis of clinico-pathologic and immunohistochemical findings in cysts treated by enucleation. J Oral Pathol Med 2009; 38: 4: 386-392.
Cottom H.E., Bshena F.I., Speight P.M., Craig G.T., Jones A.V. Histopathological features that predict the recurrence of odontogenic keratocysts. J Oral Pathol Med 2012; 41: 5: 408-414.
Zaretskaya A.S. Analiz rezul'tatov diagnostiki i ambulatornogo lecheniya patsientov s obshirnymi odontogennymi polostnymi obrazovaniyami v chelyustnykh kostyakh: Avtoref. dis. … kand. med. nauk. M 2011; 35.
Karapetyan I.S., Gubaidullina E.Ya., Tsegel'nik L.N. Predrakovye sostoyaniya, opukholi, opukholepodobnye porazheniya i kisty litsa, organov polosti rta, chelyustei i shei: M: MIA 1993; 202.
Yoshiura K., Higuchi Y. et al. Morphologic analysis of odontogenic cysts with computed tomography. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1997; 83: 712-718.
Zaretskaya A.S., Rabukhina N.A., Semkin V.A. Obshirnye odontogennye kisty razlichnogo gistologicheskogo stroeniya v rentgenologicheskom izobrazhenii. Vestnik rentgenologii i radiologii 2010; 3: 26-31.
Babichenko I.I., Semkin V.A., Usachev E.S., Katushkina A.A. Ekspressiya Ki-67 i matriksnoi metalloproteinazy-9 v follikulyarnoi kiste, keratokistoznoi odontogennoi opukholi i ameloblastome. Arkhiv patologii 2013; 1: 10-14.

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