OBJECTIVE
To determine the most significant clinical and anamnestic risk factors for the progression and postoperative recurrence of ovarian endometriosis, evaluate the effectiveness treatment to prevent post-surgical disease recurrence.
MATERIAL AND METHODS
126 case histories of patients with diagnosed ovarian endometriosis were studied, which met the inclusion criteria. An analysis was made of clinical and anamnestic data, the results of the histological method of investigation after surgical treatment, as well as a specially designed questionnaire in order to obtain long-term results of treatment and identify risk factors for relapse in patients with ovarian endometriosis. The appointment of Buserelin-Depo reduced the frequency of recurrence during the observation period.
RESULTS
Taking into account the evaluation of the data obtained, the most likely risk factors for recurrence of ovarian endometriosis were identified, and, among other things, the corresponding mathematical formula for determining this risk was proposed. To assess the accuracy of forecasting, an ROC-curve was constructed.
CONCLUSION
Based on the results of the study, the most significant risk factors are shown, and when using the derived mathematical formula, it is possible to predict the likelihood of recurrence of ovarian endometriosis, which makes it possible to timely identify a high risk group for the development of reccurence and predetermine the appropriate personalized management tactics, taking into account oncological alertness. It is necessary to prescribe treatment to prevent post-surgical disease recurrence with GnRH agnonists (Buserelin-Depo).