Dynamics of the frequency of hypercholesterolemia and hyperglycemia in patients of different ages regularly undergoing medical examination

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OBJECTIVE

To assess the frequency of hypercholesterolemia and hyperglycemia in dynamics in a cohort of the population that underwent regular medical examinations every three years (using the example of a pilot clinic).

MATERIAL AND METHODS

An observational study of the dynamics of total cholesterol (TC) and blood glucose (BG) levels was carried out in a cohort of 3794 people who underwent medical examination in a pilot clinic twice with a 3-year interval (in 2015 and 2018). The analysis was carried out according to the data of electronic medical records (EMR) where the results of biochemical studies were transferred automatically. The criteria for hyperglycemia (HG) are fasting BG >5.6 mmol/L. The criterion for hypercholesterolemia (HCS) is the total cholesterol level >5.0 mmol/L, or >4.5 mmol/L among people with diabetes mellitus (DM) or atherosclerosis-associated cardiovascular diseases (ASCVD).

RESULTS

Of the entire cohort twice examined initially 2.422 people (63.8%) had ASCVD or DM, 51.6% of them had HCS and 33.4% HG. With repeated clinical examination the target level of total cholesterol was achieved among patients with ASCVD or diabetes mellitus in 47.0%, among people without these diseases — in 48.7%; the target level of BG was achieved in 68.7% and 66.7%, respectively. New cases of HCS among patients with ASCVD or DM were detected in 52.0% of cases; and HG — in 33.2%; among people without these diseases the frequency of new HCS cases was 48.1%, HG — 31.0%.

CONCLUSION

Analysis of clinical examination data based on the indicators recorded in the EMR showed a high frequency of detection of HCS and HG both among people without diseases and among patients with ASCVD or diabetes that requires large-scale preventive and corrective measures to prevent these diseases. A low achievement of the target level of total cholesterol and BG was revealed that together indicates the unsatisfactory quality of primary and secondary prevention and dispensary observation of these patients in real practice.

Keywords:

clinical examination

primary and secondary prevention

cardiovascular diseases

medical information system

electronic medical record

Authors:

Kushunina D.V.

National Medical Research Center for Therapy and Preventive Medicine

Kalinina A.M.

National Medical Research Center for Therapy and Preventive Medicine

SPIN RSCI: 7598-4533
ORCID: 0000-0003-2458-3629

Gornyy B.E.

National Medical Research Center for Therapy and Preventive Medicine

Dubovoy I.I.

Bryansk Basic Medical College

Antonov K.A.

Bryansk City Polyclinic No. 5

Drapkina O.M.

National Medical Research Center for Therapy and Preventive Medicine;
A.I. Yevdokimov Moscow State University of Medicine and Dentistry

SPIN RSCI: 4456-1297
Scopus AuthorID: 57208852308
ResearcherID: G-8443-2016
ORCID: 0000-0002-4453-8430

Received:

07.04.2021

Accepted:

09.04.2021

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