Objective — to study interregional features of detection of hypertension, overweight, and obesity during screening the adult population. Material and methods. The detection rates for hypertension, overweight, and obesity were analyzed during the 2017 screening (for example, in patients aged 21—60 years) in 83 subjects of the Russian Federation on the basis of the data available in Reporting Form No. 131. Those were compared in the regions with different mortality rates. Results. According to the 2017 screening results, the number of all hypertensive cases among the surveyed individuals aged 21—60 years was 145.1 per 1,000; the number of newly diagnosed hypertensive patients was 23.0 cases; that of overweight and obese patients was 211.9 cases. The proportion of newly diagnosed hypertensive cases was 15.9%. There were significant fluctuations in these indicators in different subjects of the Russian Federation. The subjects of the Russian Federation with higher standardized mortality rates (SMR) from circulatory system diseases (CSDs) showed a smaller number and a lower proportion of new-onset hypertension cases, as well as a smaller number of overweight and obese cases, but a larger number of all hypertensive cases. Conclusion. The screening findings indicate a lack of activity of primary health care (PHC) facilities in the regions in actively attracting the population to undergo screening. The significant interregional differences in the frequency of hypertension, overweight, and obesity are suggestive of different levels of preventive activity of PHC facilities in the regions. The data obtained in the ranking of the subjects of the Russian Federation according to the level of SMR from CSDs indicate the greater preventive activity of PHC facilities in the regions with lower SMR. The study results confirm the importance of screening quality control, as well as the higher activity of PHC in attracting the citizens to undergo screening.