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Baturin A.K.

Federal Research Center of Nutrition and Biotechnology, Moscow, Russia

Sorokina E.Yu.

Federal Research Center of Nutrition and Biotechnology, Moscow, Russia

Keshabyants E.E.

Federal Research Center of Nutrition and Biotechnology, Moscow, Russia

Sokolnikov A.A.

Federal Research Center of Nutrition, Biotechnology and Food Safety, Moscow, Russia

Kobelkova I.V.

Federal Research Center of Nutrition and Biotechnology, Moscow, Russia

Risk assessment for vitamin D deficiency in the inhabitants of the Russian Arctic according to rs9939609 polymorphism

Authors:

Baturin A.K., Sorokina E.Yu., Keshabyants E.E., Sokolnikov A.A., Kobelkova I.V.

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Journal: Russian Journal of Preventive Medicine. 2019;22(2): 57‑61

DOI: 10.17116/profmed20192202157

Read: 1558 times

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RISK ASSESSMENT FOR VITAMIN D DEFICIENCY IN THE INHABITANTS OF THE RUSSIAN ARCTIC ACCORDING TO RS9939609 POLYMORPHISM
RISK ASSESSMENT FOR VITAMIN D DEFICIENCY IN THE INHABITANTS OF THE RUSSIAN ARCTIC ACCORDING TO RS9939609 POLYMORPHISM

To cite this article:

Baturin AK, Sorokina EYu, Keshabyants EE, Sokolnikov AA, Kobelkova IV. Risk assessment for vitamin D deficiency in the inhabitants of the Russian Arctic according to rs9939609 polymorphism. Russian Journal of Preventive Medicine. 2019;22(2):57‑61. (In Russ.)
https://doi.org/10.17116/profmed20192202157

 
 
 
Подписка 2026 Профилактическая медицина (Russian Journal of Preventive Medicine)
 
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

The relationship between FTO rs9939609 polymorphism and 25(OH)D (25-hydroxycholecalciferol) deficiency was studied among the population of the Arctic Zone of the Russian Federation (Yamal-Nenets Autonomous Area). A total of 175 people, including 135 women and 40 men, aged 19 to 75 years were examined. Among all the examinees, the indigenous population of the Arctic Zone constituted 81%, the Nenets of whom made up 98%. The studies of vitamin D concentrations in the indigenous population living in the Arctic Zone showed that the level of this vitamin was statistically significantly higher in obese people than in examinees with a BMI <30 kg/m2. This relationship was found only in women. There was a statistically significant association of the AA genotype of FTO rs9939609 polymorphism with vitamin D deficiency, which was characteristic only for the female population of the region. Examinations of the region’s newcomers revealed no correlation between vitamin D deficiency and FTO rs9939609 polymorphism.

Keywords:

vitamin D
FTO gene
genetic rs9939609 polymorphism
obesity
Arctic zone
Yamal-Nenets Autonomous Area

Authors:

Baturin A.K.

Federal Research Center of Nutrition and Biotechnology, Moscow, Russia

Sorokina E.Yu.

Federal Research Center of Nutrition and Biotechnology, Moscow, Russia

Keshabyants E.E.

Federal Research Center of Nutrition and Biotechnology, Moscow, Russia

Sokolnikov A.A.

Federal Research Center of Nutrition, Biotechnology and Food Safety, Moscow, Russia

Kobelkova I.V.

Federal Research Center of Nutrition and Biotechnology, Moscow, Russia

Close metadata

References:

  1. Gilbert R, Bonilla C, Metcalfe C, et al. Associations of vitamin D pathway genes with circulating 25-hydroxyvitamin-D, 1,25-dihydroxyvitamin-D, and prostate cancer: a nested case-control study. Cancer Causes Control. 2015;26:205-218. https://doi.org/10.1007/s10552-014-0500-5
  2. Jakubowska-Pietkiewicz E, Mlynarski W, Klich I, et al. Vitamin D receptor gene variability as a factor influencing bone mineral density in pediatric patients. Mol Biol Rep. 2012;39(5):6243-6250. https://doi.org/10.1007/s11033-012-1444-z
  3. Baturin AK, Sorokina EYu, Vrzhesinskaya OA, et al. The study of the association between rs2228570 polymorphism of VDR gene and vitamin D blood serum concentration in the inhabitants of the Russian Arctic. Voprosy pitaniya. 2016;86(4):77-84. [In Russ.)]. http://vp.geotar.ru/ru/jarticles_diet/567.html?SSr=470133ee8e12ffffffff27c__07e206160c2f11-41f9
  4. Vimaleswaran KS, Berry DJ, Lu C, et al. Causal Relationship between Obesity and Vitamin D Status: Bi-Directional Mendelian Randomization Analysis of Multiple Cohorts. PLoS Med. 2013;10(2):e1001383. PLoS Med. 10(2):e1001383. https://doi.org/10.1371/journal.pmed.1001383
  5. Snijder M. Adiposity in relation to vitamin D status and parathyroid hormone levels: a population-based study in older men and women. J Clin Endocrinol Metab. 2005;90(7):4119-4123. https://doi.org/10.1210/jc.2005-0216
  6. Turer CB, Lin H, Flores G. Prevalence of Vitamin D Deficiency Among Overweight and Obese US Children. Pediatrics. 2013;131:e152-e161. https://doi.org/10.1542/peds.2012-1711
  7. Lourenço BH, Qi L, Willett WC, Cardoso MA. FTO Genotype, Vitamin D Status, and Weight Gain During Childhood Diabetes. 2014;63:808-814. https://doi.org/10.2337/db13-1290
  8. Robinson C, Chiang M, Thompson SN, Sondike SB. Occurrence of vitamin D deficiency in pediatric patients at high risk in West Virginia. South Med J. 2012;105:504-507. https://doi.org/10.1097/SMJ.0b013e3182675e8a
  9. Tamer G, Mesci B, Tamer I, Kilic D, Arik S. Is vitamin D deficiency an independent risk factor for obesity and abdominal obesity in women? Endocrynol Pol. 2012;63(3):196-201. https://pdfs.semanticscholar.org/2998/57f408f0e7ef3bada901b0f6bff68efd94ad.pdf
  10. Karonova TL, Grineva EN, Mikheeva EP, et al. The level of vitamin D and its relationship with the amount of fatty tissue and adipocytokine content in the women of reproductive age. Problems of Endocrinology. 2012;58(6):19-23. (In Russ.) https://www.mediasphera.ru/issues/problemy-endokrinologii/2012/6/030375- 9660201264 (https://www.mediasphera.ru/issues/problemy-endokrinologii/2012/6/030375-9660201264)
  11. Sneve M, Figenschau Y, Jorde R. Supplementation with cholecalciferol does not result in weight reduction in overweight and obese subjects. Eur J Endocrinol. 2008;159:675-684. https://doi.org/10.1530/EJE-08-0339
  12. Harbron J, Merwe L, Zaahl MG, et al. Fat mass and obesity-associated (FTO) gene polymorphisms are associated with physical activity, food intake, eating behaviors, psychological health, and modeled change in body mass index in overweight/obese caucasian adults. Nutrients. 2014;6:3130-3152. https://doi.org/10.3390/nu6083130
  13. Hinney A, Nguye TT, Schera A, et al. Genome wide association (GWA) study for early onset extreme obesity supports the role of fat mass and obesity associated gene (FTO) variants. PLoS One. 2007;2(12):1-5. https://doi.org/10.1371/journal.pone.0001361
  14. Baturin AK, Sorokina EYu, Pogozheva AV, et al. Regional features of obesity-associated gene polymorphism (rs9939609 FTO gene and gene Trp64Arg ADRB3) in Russian population. Voprosy pitaniya. 2014;83(2):35-41. (In Russ.) http://vp.geotar.ru/ru/jarticles_diet/261.html?SSr=470133ee8e12ffffffff27c__07e206160c2f11-41f9 (http://vp.geotar.ru/ru/jarticles_diet/261.html?SSr=470133ee8e12ffffffff27c__07e206160c2f11-41f9)
  15. Baturin AK, Sorokina EYu, Pogozheva AV, et al. The association of rs993609 polymorphisms of gene FTO and rs659366 polymorphisms of gene UCP2 with obesity among Arctic Russian population. Voprosy pitaniya. 2017;86(3):33-39. (In Russ.) http://vp.geotar.ru/ru/jarticles_diet/546.html?SSr=470133ee8e12ffffffff27c__07e206160c2f11-41f9
  16. Lourenço BH, Qi L, Willett WC, Cardoso MA. FTO Genotype, Vitamin D Status, and Weight Gain During Childhood. Diabetes. 2014;63:808-814. https://doi.org/10.2337/db13-1290
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