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Grinshtein Yu.I.

Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Ministry of Health of Russia

Shabalin V.V.

Saint-Petersburg Institute of Ear, Nose, Throat and Speech, St.-Petersburg, Russia, 190013

Ruf R.R.

Department of Perinatology, Obstetrics, and Gynecology, Faculty of General Medicine, V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Ministry of Health of Russia, Krasnoyarsk, Russia

Petrova M.M.

Kafedra poliklinicheskoĭ terapii i semeĭnoĭ meditsiny s kursom poslediplomnogo obrazovaniia Krasnoiarskogo gosudarstvennogo meditsinskogo universiteta im. prof. V.F. Voĭno-Iasenetskogo

Shalnova S.A.

National Medical Research Center for Preventive Medicine, Moscow, Russia

Prevalence of dyslipidemia among the population of a large region of Eastern Siberia and its association with sociodemographic and behavioral factors

Authors:

Grinshtein Yu.I., Shabalin V.V., Ruf R.R., Petrova M.M., Shalnova S.A.

More about the authors

Journal: Russian Journal of Preventive Medicine. 2018;21(5): 63‑69

DOI: 10.17116/profmed20182105163

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Table of contents

PREVALENCE OF DYSLIPIDEMIA AMONG THE POPULATION OF A LARGE REGION OF EASTERN SIBERIA AND ITS ASSOCIATION WITH SOCIODEMOGRAPHIC AND BEHAVIORAL FACTORS
PREVALENCE OF DYSLIPIDEMIA AMONG THE POPULATION OF A LARGE REGION OF EASTERN SIBERIA AND ITS ASSOCIATION WITH SOCIODEMOGRAPHIC AND BEHAVIORAL FACTORS

To cite this article:

Grinshtein YuI, Shabalin VV, Ruf RR, Petrova MM, Shalnova SA. Prevalence of dyslipidemia among the population of a large region of Eastern Siberia and its association with sociodemographic and behavioral factors. Russian Journal of Preventive Medicine. 2018;21(5):63‑69. (In Russ.)
https://doi.org/10.17116/profmed20182105163

 
 
 
Подписка 2026 Профилактическая медицина (Russian Journal of Preventive Medicine)
 
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Abstract:

Lipid metabolic parameters at the population level are important in assessing the control and prevention of cardiovascular risk factors. Objective — to investigate the prevalence of lipid metabolic disturbances among the urban and rural population of the Krasnoyarsk Territory and also to reveal the possible association with sociodemographic and behavioral factors. Material and methods. The prevalence of dyslipidemia was studied in the framework of the epidemiological study ESSE-RF. The analysis included 1603 people aged 25—64 years, who had been selected by random sampling among the urban and rural populations of Krasnoyarsk Territory. Statistical processing was performed using the programs IBM SPSS v. 22 and LibreOffice v. 5. Results. The mean hypercholesterolemia (HC) prevalence rate estimated by the level of total cholesterol at the examination and in the use of lipid-lowering drugs was 59.7±2.5%; this was higher in women (66.6±3.1%) than in men (49.2±4.0%) (p<0.001). The prevalence of HC significantly increased with increasing age. Urban versus rural dwellers had higher HC (62.7±2.9 and 51.6±4.9%) (p<0.001). The overall prevalence of elevated low-density lipoprotein cholesterol (LDL-C) was 56.3±2.5%. Elevated LDL-C levels were more frequently noted in men. Lower high-density lipoprotein (HDL)-C was more common in rural dwellers than in urban ones (27.4±4.3% and 14.1±2.1%; p<0.001). The detection rate of hypertriglyceridemia (HT) was higher in men than in women (29.0±3.6% and 22.8±2.1%; p<0.001). Conclusion. The prevalence of HC in the Krasnoyarsk Territory (with consideration for those successfully taking statins) was 59.7±2.5%, which was comparable with the mean Russian indicators (according to the data of the ESSE-RF study). Regression analysis revealed a significant impact of gender on a change in all lipid fractions, except HDL-C; that of age on all types of dyslipidemia, except HDL-C; that of smoking, alcohol consumption, and obesity on a reduction in HDL-C; that of abdominal obesity on a decrease in HDL-C and on an increase in triglycerides.

Keywords:

dyslipidemia
cholesterol
prevalence
epidemiology

Authors:

Grinshtein Yu.I.

Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Ministry of Health of Russia

Shabalin V.V.

Saint-Petersburg Institute of Ear, Nose, Throat and Speech, St.-Petersburg, Russia, 190013

Ruf R.R.

Department of Perinatology, Obstetrics, and Gynecology, Faculty of General Medicine, V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Ministry of Health of Russia, Krasnoyarsk, Russia

Petrova M.M.

Kafedra poliklinicheskoĭ terapii i semeĭnoĭ meditsiny s kursom poslediplomnogo obrazovaniia Krasnoiarskogo gosudarstvennogo meditsinskogo universiteta im. prof. V.F. Voĭno-Iasenetskogo

Shalnova S.A.

National Medical Research Center for Preventive Medicine, Moscow, Russia

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