Objective — to analyze the impact of socioeconomic features on the population-based risk of coronary heart disease (CHD) due to cardiovascular risk factors (CVRFs). Subject and methods. This investigation was conducted within the multicenter epidemiological study ESSE-RF in the Kemerovo Region. It was concerned with a random population sample of 1628 men and women aged 25—64 years. CVRFs, such as lifestyle, a number of diseases, and biochemical indicators of dyslipidemia, were considered as CVRs. Among the socioeconomic indicators, marital status, education, employment/unemployment, and income were considered. The load of SVRFs, which was composed of the ratio of their prevalence in the study subpopulations to that in the entire population, as well as the contribution of these CVRFs to the incidence of CHD, was calculated to assess the population-based risk of CHD caused by SVRFs. Results. The differences in the spread of CVRFs in the socioeconomic cohorts of the population determine distinctions in the population-based risk of CHD. The additional risk for CHD due to CVRFs increases up to 3.0% in married men and decreases to –0.9% in single men; it increases up to 10.3% in unemployed one. The additional risk for CHD caused by CVRFs reduces to 4.5% in women having higher education in relation to the regional values and does to –2.2% in employed women. Conclusion. This investigation suggests that there are distinctions in the population-based risk of CHD due to CVRFs in the socioeconomic cohorts of the population. The higher spread of a number of CVRFs among married or unemployed men determines the increased additional risk of CHD. The low spread of CVRs and accordingly the low additional risk of CHD caused by these SVRFs are observed in women with higher education and in those who are employed.