Objective. To assess the conformity of prescriptions and monitoring of lipid-lowering therapy to clinical guidelines, adherence to statin treatment in a cohort of coronary heart disease (CHD) patients who underwent a coronary angiography (CAG) procedure at the State Research Center for Preventive Medicine (SRCPM) in 2004-2008 on the basis of the data of the CHD PROGNOSIS Register supplemented by the results of their examination and questioning. Material and methods. The investigation used the CHD PROGNOSIS Register database. The final analysis included the data of 303 patients from a cohort of those who had verified CHD and had undergone a CAG procedure at the SRCPM in 2004-2008 and made a control visit. The patients' mean age was 62 years. One hundred and seventy-five (57.8%) patients had sustained different vascular catastrophes (acute myocardial infarction, cerebral stroke); 128 (42.2%) people had no evidence of cardiovascular events. All the patients gave a written informed consent to participate in the study. The patients underwent a general survey, examination, blood biochemical test, and treatment adherence questionnaire assessment. Results. Statins (mainly original ones) were prescribed in more than 86% of the patients with CHD at the Clinic of the Research Center. 67% of the patients proved to be adherent to statin treatment an average of 3.9 years after hospitalization. However, in most of them, the original drugs were substituted for their generics. The questionnaire surgery showed that cholesterol awareness was 94.1%; 18 (5.9%) people knew nothing about lipid metabolic parameters. 214 (70.6%) study participants knew about their cholesterol levels and 89 (29.4%) did not. 271 (89.4%) people were aware of cholesterol-lowering drugs and 32 (10.6%) were not. Conclusion. The results of the investigation have demonstrated the satisfactory patient awareness of cardiovascular risk factors and basic treatments for lipid metabolic disturbances; however, patient adherence to statin therapy remains poor although there is a positive trend towards higher compliance with treatment with these drugs.