The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.
Korotkova T.D.
National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov of Ministry of Healthcare of Russia, Moscow, Russia
Adamyan L.V.
Department of Reproductive Medicine and Surgery, Faculty of Postgraduate Professional Education, A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of Russia, Moscow, Russia
Stepanian A.A.
Kafedpa peppoduktivnoĭ meditsiny i xipupgii Mockovckogo univepciteta meditsiny i ctomatologii
Krechetova L.V.
National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov of Ministry of Healthcare of Russia, Moscow, Russia
Vanko L.V.
National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov of Ministry of Healthcare of Russia, Moscow, Russia
Cellular and molecular factors of innate immunity in the pathogenesis of external genital endometriosis in women (a review)
Journal: Russian Journal of Human Reproduction. 2018;24(6): 22‑31
Views: 2695
Downloaded: 53
To cite this article:
Korotkova TD, Adamyan LV, Stepanian AA, Krechetova LV, Vanko LV. Cellular and molecular factors of innate immunity in the pathogenesis of external genital endometriosis in women (a review). Russian Journal of Human Reproduction.
2018;24(6):22‑31. (In Russ., In Engl.)
https://doi.org/10.17116/repro20182406122
ABSTRACT Literature data analysis of the role of cellular and humoral factors of inborn immunity in the pathogenesis of endometriosis is presented. Review includes the data from foreign and domestic articles for a research topic, published in the Pubmed database journals over the past 15 years. The data about contribution of cellular and humoral factors of inborn immunity acting at the local and systemic level to the pathogenesis of endometriosis are presented. Given the polyfunctionality of cells and cytokines which are the pleiotropic proteins with significant redundancy of functions, it is still difficult to determine how they affect the pathogenesis of endometriosis. The factors of inborn immunity are the significant ones in the development of endometrioid lesions. The presented data expand the knowledge of pathogenesis of endometriosis and indicate to the need for further study of the role of these factors. A deeper understanding of their mechanisms can help to improve the management of the women with external genital endometriosis and the possibility of targeted therapy application, including the influence to the factors of inborn immunity.
Authors:
Korotkova T.D.
National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov of Ministry of Healthcare of Russia, Moscow, Russia
Adamyan L.V.
Department of Reproductive Medicine and Surgery, Faculty of Postgraduate Professional Education, A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of Russia, Moscow, Russia
Stepanian A.A.
Kafedpa peppoduktivnoĭ meditsiny i xipupgii Mockovckogo univepciteta meditsiny i ctomatologii
Krechetova L.V.
National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov of Ministry of Healthcare of Russia, Moscow, Russia
Vanko L.V.
National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov of Ministry of Healthcare of Russia, Moscow, Russia
List of references:
Close metadata
Email Confirmation
An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.
Email Confirmation
Log in to the site using your account in one of the services
We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.