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Nazarenko T.A.

Kafedra akusherstva, ginekologii, perinatologii i reproduktologii fakul'teta poslediplomnogo professional'nogo obucheniia vracheĭ Moskovskoĭ meditsinskoĭ akademii im. I.M. Sechenova;
Nauchnyĭ tsentr akusherstva, ginekologii i perinatologii im. akad. V.I. Kulakova

Parokonnaia A.A.

Rossiĭskiĭ nauchnyĭ onkologicheskiĭ tsentr im. N.N. Blokhina RAMN

Sharipova N.Iu.

FGBU "Nauchnyĭ tsentr akusherstva, ginekologii i perinatologii im. V.I. Kulakova" Minzdravsotsrazvitiia Rossii, Moskva

THE USE OF AROMATASE INHIBITORS IN ART IN WOMEN WITH BREAST CANCER

Authors:

Nazarenko T.A., Parokonnaia A.A., Sharipova N.Iu.

More about the authors

Journal: Russian Journal of Human Reproduction. 2012;(2): 72‑76

Read: 3176 times

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Table of contents

THE USE OF AROMATASE INHIBITORS IN ART IN WOMEN WITH BREAST CANCER
THE USE OF AROMATASE INHIBITORS IN ART IN WOMEN WITH BREAST CANCER

To cite this article:

Nazarenko TA, Parokonnaia AA, Sharipova NIu. THE USE OF AROMATASE INHIBITORS IN ART IN WOMEN WITH BREAST CANCER. Russian Journal of Human Reproduction. 2012;(2):72‑76. (In Russ.)

 
Подписка 2026 Проблемы репродукции (Russian Journal of Human Reproduction)
 
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

The method of aromatase inhibitors use in stimulation protocols for IVF in patients with breast cancer to preserve their fertility via embryo cryopreservation before chemotherapy is presented. Aromatase inhibitors significantly reduce serum estrogen level without interrupting oogenesis/embryogenesis.

Keywords:

breast cancer
aromatase inhibitors
fertility preservation

Authors:

Nazarenko T.A.

Kafedra akusherstva, ginekologii, perinatologii i reproduktologii fakul'teta poslediplomnogo professional'nogo obucheniia vracheĭ Moskovskoĭ meditsinskoĭ akademii im. I.M. Sechenova;
Nauchnyĭ tsentr akusherstva, ginekologii i perinatologii im. akad. V.I. Kulakova

Parokonnaia A.A.

Rossiĭskiĭ nauchnyĭ onkologicheskiĭ tsentr im. N.N. Blokhina RAMN

Sharipova N.Iu.

FGBU "Nauchnyĭ tsentr akusherstva, ginekologii i perinatologii im. V.I. Kulakova" Minzdravsotsrazvitiia Rossii, Moskva

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References:

  1. Jeruss J.S., Woodruff T. Preservation of Fertility in Patients with Cancer. N Engl. J Med 2009; 360: 9: 902-911.
  2. Lee S., Schover L., Partridge A., Patrizio P., Wallace W. H., Hagerty K., Beck L., Brennan L., Oktay K. American Society of Clinical Oncology Recommendations on Fertility Preservation in Cancer Patients. J Clin Oncol 2006; 24: 2917-2931.
  3. Ajala T., Rafi J., Larsen-Disney P., Howell R. Fertility preservation for cancer patients: a review. Obstet Gynecol Int 2010; 2010: 160386.
  4. Nazarenko T.A., Dmitriev D.V. Ingibitory aromatazy v reproduktivnoi meditsine (obzor literatury). Probl reprod 2007; 1: 14-20.
  5. Howell A., Cuzick J., Baum M., Buzdar A., Dowsett M., Forbes J.F., Hoctin-Boes G., Houghton J., Locker G.Y., Tobias J.F. Results of the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trail after completion of 5 years? adjuvant treatment for breast cancer. Lancet 2005; 365: 60-62.
  6. Shuyang Yao., Binghe Xu., Qing Li., Pin Zhang, Peng Yuan., Jiayu Wang., Fei Ma., Ying Fan. Goserelin plus letrozole as first- or second-line hormonal treatment in premenopausal patients with advanced breast cancer. Endocrine J 2011; 58: 6: 509-516.
  7. Kesisis G., Makris A., Miles D. Update on the use of aromatase inhibitors in early-stage breast cancer. Breast Cancer Res 2009; 11: 211-222.
  8. Azim A., Costantini-Ferrando M., Kutluk O. Safety of Fertility Preservation by Ovarian Stimulation With Letrozole and Gonadotropins in Patients With Breast Cancer: a Prospective Controlled Study. Clin Oncol 2008; 26: 16: 2630-2635.
  9. Polyzos N.P., Mauri D., Tzioras S. Letrozole in ovulation induction: time to make decisions. Hum Reprod Update 2009; 15: 2: 263-264.
  10. Oktay K., Hourvitz A., Sahin G. et al. Letrozole reduces estrogen and gonadotropin exposure in women with breast cancer undergoing ovarian stimulation before chemotherapy. J Clin Endocrinol Metab 2006; 91: 10: 3885-3890.
  11. Amr A. Azim, Costantini-Ferrando M., Lostritto K., Kutluk Oktay. Relative potencies of an astrozole and letrozole to suppress estradiol in breast cancer patients underoing ovarian stimulation before in vitro fertilization. J Clin Endocrinol Metab 2007; 92: 6: 2197-2200.
  12. Bilijan M., Hemming R., Brassard N. The outcome of 150 babies following the treatment with letrozole and gonadotropins. Fertil Steril 2005; 84: Supp 1: S95.
  13. Tulandi T., Martin J., Al-Fadhli R., Kabli N., Forman R., Hitkari J., Librach C., Greenblatt E., Casper R.F. Congenital malformations among 911 newborns conceived after infertility treatment with letrozole or clomiphene citrate. Fertil Steril 2006; 85: 1761-1765.
  14. Hu Y., Cortvrindt Smitz J. Effects of aromatase inhibition on in vitro follicle and oocyte development analyzed by early preantral mouse follicle culture. Mol Reprod Dev 2002; 61: 549-559.
  15. Luthra R., Kirma N., Jones J., Tekmal R.R. Use of letrozole as a chemopreventive agent in aromatase overexpressing transgenic mice. J Steroid Chem Mol Biol 2003; 86: 461-467.
  16. Amr A. Azim, Maria Costantini-Ferrando, Kutluk Oktay. Safety of fertility preservation by ovarian stimulation with letrozole and gonadotropins in patients with breast cancer: a prospective controlled study. J Clin Oncol 2008; 26: 16: 2630-2635.
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