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Dedov I.I.

Endocrinology Research Centre

Melnichenko G.A.

I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia, Moscow, Russia;
Endocrinology Research Center, Ministry of Health of Russia, Moscow, Russia

Rozhinskaia L.Ia.

FGU Éndokrinologicheskiĭ nauchnyĭ tsentr, Moskva

Dzeranova L.K.

ndokrinologicheskiĭ nauchnyĭ tsentr Minzdrava RF, Moskva

Pigarova E.A.

FGU Éndokrinologicheskiĭ nauchnyĭ tsentr Minzdravsotsrazvitiia RF, Moskva

Kadashev B.A.

NII neĭrokhirurgii im. N.N. Burdenko RAMN, Moskva

Grigor'ev A.Iu.

FGU Éndokrinologicheskiĭ nauchnyĭ tsentr, Moskva

Astaf'eva L.I.

NII neĭrokhirurgii im. N.N. Burdenko RAMN, Moskva

Shishkina L.V.

Burdenko Neurosurgery Institute, Moscow, Russia

Vorontsov A.V.

FGU Éndokrinologicheskiĭ nauchnyĭ tsentr Minzdravsotsrazvitiia RF

Lipatenkova A.K.

Endocrinology Research Centre, Moscow, Russia

Vorotnikova S.Iu.

ndokrinologicheskiĭ nauchnyĭ tsentr Minzdrava RF, Moskva

Pituitary incidentalomas: the clinical picture, diagnostics, differential diagnostics, and methods of treatment

Authors:

Dedov I.I., Melnichenko G.A., Rozhinskaia L.Ia., Dzeranova L.K., Pigarova E.A., Kadashev B.A., Grigor'ev A.Iu., Astaf'eva L.I., Shishkina L.V., Vorontsov A.V., Lipatenkova A.K., Vorotnikova S.Iu.

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Journal: Problems of Endocrinology. 2015;61(3): 57‑68

DOI: 10.14341/probl201561357-68

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PITUITARY INCIDENTALOMAS: THE CLINICAL PICTURE, DIAGNOSTICS, DIFFERENTIAL DIAGNOSTICS, AND METHODS OF TREATMENT
PITUITARY INCIDENTALOMAS: THE CLINICAL PICTURE, DIAGNOSTICS, DIFFERENTIAL DIAGNOSTICS, AND METHODS OF TREATMENT

To cite this article:

Dedov II, Melnichenko GA, Dedov II, et al. . Pituitary incidentalomas: the clinical picture, diagnostics, differential diagnostics, and methods of treatment. Problems of Endocrinology. 2015;61(3):57‑68. (In Russ.)
https://doi.org/10.14341/probl201561357-68

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Incidentalomas are the most common neoplasms in the hypothalamic-pituitary region. Diagnostics, treatment strategy, and indications for the surgical intervention on the patients with these tumours pose a serious challenge for a wide circle of specialists. The diagnostic problems arise from the absence of the specific clinical signs and symptoms as well as the reliable biochemical markers of the disease. The modern laboratory methods do not allow to reveal the pathological hormonal secretion during the diagnostic study, predisposition of the neoplasm to the invasive and infiltrative growth, and signs of its «aggressiveness». This considerably complicates the choice of the optimal surgical strategy and the evaluation of the long-term results of the treatment. Bearing in mind the importance of the problem under consideration, the working group was set up for the development of federal recommendations on the treatment of pituitary incidentalomas based on the principles of evidence-based medicine. The experience accumulated by the domestic and international experts was summarized in the federal clinical guidelines on pituitary incidentalomas containing the available information about these neoplasms.

Keywords:

pituitary incidentalomas
pituitary incidentalomas
diagnostics
diagnostics
differential diagnostics
differential diagnostics
surgical treatment
surgical treatment
pharmacotherapy
pharmacotherapy
pituitary incidentalomas
pituitary incidentalomas
diagnostics
diagnostics
differential diagnostics
differential diagnostics
surgical treatment
surgical treatment
pharmacotherapy
pharmacotherapy

Authors:

Dedov I.I.

Endocrinology Research Centre

Melnichenko G.A.

I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia, Moscow, Russia;
Endocrinology Research Center, Ministry of Health of Russia, Moscow, Russia

Rozhinskaia L.Ia.

FGU Éndokrinologicheskiĭ nauchnyĭ tsentr, Moskva

Dzeranova L.K.

ndokrinologicheskiĭ nauchnyĭ tsentr Minzdrava RF, Moskva

Pigarova E.A.

FGU Éndokrinologicheskiĭ nauchnyĭ tsentr Minzdravsotsrazvitiia RF, Moskva

Kadashev B.A.

NII neĭrokhirurgii im. N.N. Burdenko RAMN, Moskva

Grigor'ev A.Iu.

FGU Éndokrinologicheskiĭ nauchnyĭ tsentr, Moskva

Astaf'eva L.I.

NII neĭrokhirurgii im. N.N. Burdenko RAMN, Moskva

Shishkina L.V.

Burdenko Neurosurgery Institute, Moscow, Russia

Vorontsov A.V.

FGU Éndokrinologicheskiĭ nauchnyĭ tsentr Minzdravsotsrazvitiia RF

Lipatenkova A.K.

Endocrinology Research Centre, Moscow, Russia

Vorotnikova S.Iu.

ndokrinologicheskiĭ nauchnyĭ tsentr Minzdrava RF, Moskva

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