The clinical and instrumental rationale for the choice of therapy of arterial hypertension in the patients presenting with diabetes mellitus

Tatarchenko I.P.

GBOU DPO "Penzenskiĭ institut usovershenstvovaniia vracheĭ" MZ RF

Pozdniakova N.V.

GBOU DPO "Penzenskiĭ institut usovershenstvovaniia vracheĭ" MZ RF;
FGBUZ "Mediko-sanitarnaia chast' #59" FMBA Rossii, Penza

Mordovina A.G.

GBOU DPO "Penzenskiĭ institut usovershenstvovaniia vracheĭ" MZ RF;
FGBUZ "Mediko-sanitarnaia chast' #59" FMBA Rossii, Penza

The clinical and instrumental rationale for the choice of therapy of arterial hypertension in the patients presenting with diabetes mellitus

Authors:

Tatarchenko I.P., Pozdniakova N.V., Mordovina A.G.

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Journal: Problems of Endocrinology. 2012;58(6): 8‑12

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To cite this article:

Tatarchenko IP, Pozdniakova NV, Mordovina AG. The clinical and instrumental rationale for the choice of therapy of arterial hypertension in the patients presenting with diabetes mellitus. Problems of Endocrinology. 2012;58(6):8‑12. (In Russ.)

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Cardiovascular disorders are the main cause of high disability and mortality rates among the patients with diabetes mellitus. The objective of the present work was to estimate the clinical and hemodynamic characteristics during the treatment of arterial hypertension with the use of olmesartan (hypertension/angiotensin II receptor antagonist, ARA) in the patients with type 2 diabetes mellitus suffering diastolic heart failure. The study included 56 patients (26 men and 30 women) of the mean age 58.2±5.3 years. They were given a course of olmesartan (cardosal) therapy 40 weeks in duration. This treatment was shown to result in positive dynamics of structural and geometric characteristics of the left ventricle and its diastolic function in conjunction with the improvement of the vasomotor function of arterial endothelium.

Keywords:

diabetes mellitus

angiotensin II receptor antagonists

Authors:

Tatarchenko I.P.

GBOU DPO "Penzenskiĭ institut usovershenstvovaniia vracheĭ" MZ RF

Pozdniakova N.V.

GBOU DPO "Penzenskiĭ institut usovershenstvovaniia vracheĭ" MZ RF;
FGBUZ "Mediko-sanitarnaia chast' #59" FMBA Rossii, Penza

Mordovina A.G.

GBOU DPO "Penzenskiĭ institut usovershenstvovaniia vracheĭ" MZ RF;
FGBUZ "Mediko-sanitarnaia chast' #59" FMBA Rossii, Penza

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