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Zakharova M.A.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center

Zikiryakhodzhaev A.D.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center;
I.M. Sechenov First Moscow State Medical University (Sechenov University);
Peoples’ Friendship University of Russia named after Patrice Lumumba

Saribekyan, E.K.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center

Ablitsova N.V.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center

Efanov, V.V.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center

Fokina T.Yu.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center

Biopsy of the sentinel lymph node and the possibility of performing breast-conserving surgery for the non-inflammatory invasive breast cancers with edema

Authors:

Zakharova M.A., Zikiryakhodzhaev A.D., Saribekyan, E.K., Ablitsova N.V., Efanov, V.V., Fokina T.Yu.

More about the authors

Journal: P.A. Herzen Journal of Oncology. 2025;14(4): 96‑101

DOI: 10.17116/onkolog20251404196

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Table of contents

BIOPSY OF THE SENTINEL LYMPH NODE AND THE POSSIBILITY OF PERFORMING BREAST-CONSERVING SURGERY FOR THE NON-INFLAMMATORY INVASIVE BREAST CANCERS WITH EDEMA
BIOPSY OF THE SENTINEL LYMPH NODE AND THE POSSIBILITY OF PERFORMING BREAST-CONSERVING SURGERY FOR THE NON-INFLAMMATORY INVASIVE BREAST CANCERS WITH EDEMA

To cite this article:

Zakharova MA, Zikiryakhodzhaev AD, Saribekyan, EK, Ablitsova NV, Efanov, VV, Fokina TYu. Biopsy of the sentinel lymph node and the possibility of performing breast-conserving surgery for the non-inflammatory invasive breast cancers with edema. P.A. Herzen Journal of Oncology. 2025;14(4):96‑101. (In Russ.)
https://doi.org/10.17116/onkolog20251404196

Подписка 2026 Онкология. Журнал им. П.А. Герцена (P.A. Herzen Journal of Oncology)
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Abstract:

Breast cancer (BC), accompanied by edema, is one of the most aggressive forms of malignant neoplasms. The gold standard for the treatment of breast cancer with skin edema (T4bN any M0) is a complex method, including neoadjuvant drug therapy followed by radical mastectomy, postoperative radiation therapy and, if indicated, adjuvant drug therapy. Based on a study of the medical literature and our clinical experience, we concluded that it is possible to identify a group of patients with limited skin swelling and favourable clinical and morphological prognostic factors who can undergo de-escalation of surgical intervention. De-escalation is possible in the form of reducing the volume of lymphadenectomy using the sentinel lymph node biopsy technique, as well as performing breast-conserving surgery and skin-sparing mastectomies with reconstruction.

Keywords:

Breast cancer
edema
sentinel lymph node biopsy
literature review
breast-conserving surgery
T4b

Authors:

Zakharova M.A.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center

Zikiryakhodzhaev A.D.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center;
I.M. Sechenov First Moscow State Medical University (Sechenov University);
Peoples’ Friendship University of Russia named after Patrice Lumumba

Saribekyan, E.K.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center

Ablitsova N.V.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center

Efanov, V.V.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center

Fokina T.Yu.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center

Received:

22.05.2024

Accepted:

04.08.2024

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