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Balayan E.O.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of the Ministry of Health of Russia

Khoronenko V.E.

P.A. Herzen Moscow Oncology Research Institute, Branch, National Medical Radiology Research Center

Zikiryakhodzhaev A.D.

I.M. Sechenov First Moscow State Medical University (Sechenov University) of the Ministry of Russia;
P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of the Ministry of Russia;
Peoples’ Friendship University of Russia

Use of vasopressors in free flap reconstructive plastic surgery

Authors:

Balayan E.O., Khoronenko V.E., Zikiryakhodzhaev A.D.

More about the authors

Journal: P.A. Herzen Journal of Oncology. 2021;10(6): 89‑94

DOI: 10.17116/onkolog20211006189

Views: 788

Downloaded: 26

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Table of contents

USE OF VASOPRESSORS IN FREE FLAP RECONSTRUCTIVE PLASTIC SURGERY
USE OF VASOPRESSORS IN FREE FLAP RECONSTRUCTIVE PLASTIC SURGERY

To cite this article:

Balayan EO, Khoronenko VE, Zikiryakhodzhaev AD. Use of vasopressors in free flap reconstructive plastic surgery. P.A. Herzen Journal of Oncology. 2021;10(6):89‑94. (In Russ.)
https://doi.org/10.17116/onkolog20211006189

Подписка 2025-2 (P.A. Herzen Journal of Oncology)
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Currently, reconstruction using autologous freely displaced tissues is widely used in breast cancer surgery. Anesthetic management for operations using microsurgical procedures along with surgical professionalism plays an important role in the further survival of free flaps. Adequate autograft perfusion is required for microanastomoses to function. Hemodynamic stability is one of the key positions in the intraoperative and postoperative management of this category of patients. In the perioperative period, the hemodynamics of patients is modulated mainly by infusion therapy and vasoactive pharmacological support. Vasopressors are assumed to adversely affect free flap survival, causing peripheral vasoconstriction with a consequent reduction in overall graft perfusion. Just the same, the doctrinal banning of vasopressors during breast microvascular reconstruction is still a matter of controversy. The purpose of this literature review is to evaluate the effect of vasopressors on the incidence of perioperative complications in free-flap reconstructive plastic surgery for cancer.

Keywords:

anesthetic maintenance
vasopressors
norepinephrine
phenylephrine
free flap
adrenoceptors
DIEP flap
oncology

Authors:

Balayan E.O.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of the Ministry of Health of Russia

Khoronenko V.E.

P.A. Herzen Moscow Oncology Research Institute, Branch, National Medical Radiology Research Center

Zikiryakhodzhaev A.D.

I.M. Sechenov First Moscow State Medical University (Sechenov University) of the Ministry of Russia;
P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of the Ministry of Russia;
Peoples’ Friendship University of Russia

Received:

06.07.2021

Accepted:

20.07.2021

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