Primary outcomes after major anatomical liver resections in infants at the National Children’s Medical Center

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OBJECTIVE

To analyze the results of major right-sided hemihepatectomies in infants with various neoplasms.

MATERIAL AND METHODS

There were 3 right-sided major hemihepatectomies in pediatric patients aged 5—10 months for different neoplasms between December 2023 and May 2024. Perioperative data of patients, indications for liver resection, and postoperative outcomes were retrospectively analyzed.

RESULTS. M

Ean age of patients was 7.3 months. The indications for liver resection were hepatoblastoma in two cases and anastomosing hemangioma in one case. Two patients underwent anatomical resection of the right hepatic lobe, and one patient underwent extended right-sided hemihepatectomy. Mean surgery time was 230 min, blood loss — 133 ml. No surgical complications were observed. Mean hospital-stay after surgery was 7.3 days. Patients with hepatoblastoma received postoperative chemotherapy. No recurrence of neoplasms was detected throughout the follow-up period.

CONCLUSION

Primary results of liver resections demonstrated feasibility and safety of radical major hemihepatectomies in pediatric patients with large liver neoplasms. These outcomes are comparable with world literature. Such interventions in infants necessitate substantial experience in hepatobiliary surgery. Patients with hepatoblastoma require post-hepatectomy chemotherapy. There is a need to develop primary outpatient services for liver tumor screening and timely diagnosis in pediatric patients.

Keywords:

liver resection

major hemihepatectomy

pediatric surgery

oncology

Authors:

Semash K.O.

National Children’s Medical Center

ORCID: 0000-0001-5830-5235

Dzhanbekov T.A.

National Children’s Medical Center

ORCID: 0000-0002-8857-947X

Received:

21.06.2024

Accepted:

04.07.2024

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