Minimally invasive surgery for cardioesophageal cancer

Domrachev S.A.; Izrailov R.E.; Kucher S.A.

doi:https://doi.org/10.17116/onkolog2019801157

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Abstract:

The paper gives the results of analyzing the ongoing studies of minimally invasive surgery for cardioesophageal cancer. Surgery via mini-invasive approaches is known to be characterized by fewer postoperative complications and a shorter rehabilitation in patients after surgical treatment than traditional open surgical interventions. However, whether the principles of cancer radicalism can be upheld has not yet been finally resolved. Due to the ambiguity of fundamental data on the nature of cardioesophageal cancer and as a consequence of the lack of a unified classification of the disease, there is no single approach to surgically treating patients with this nosological entity. In addition, there is no optimal way to create esophagogastric anastomoses in surgical practice. The existing various modifications of manual and machine stitches may reduce the risks of complications only in a small percentage of cases. In this connection, the abundance of unresolved issues confirms the need for a comprehensive analysis of the experience of foreign and Russian surgeons in order to develop and improve optimal treatment procedures for patients with esophagogastric junction cancer.

Keywords:

cardioesophageal cancer

minimally invasive surgery

esophageal surgery

anastomotic incompetence

Authors:

Domrachev S.A.

Kafedra fakul'tetskoĭ khirurgii #2 lechebnogo fakul'teta GBOU VPO MGMSU im. A.I. Evdokimova Minzdravsotsrazvitiia Rossii, GBUZ GKB #70 DZM

Izrailov R.E.

kafedra fakul'tetskoĭ khirurgii #2 MGMSU

SPIN RSCI: 7121-2776
Scopus AuthorID: 56571607000
ORCID: 0000-0001-7254-5411

Kucher S.A.

Chair of Faculty-Based Surgery №2, Evdokimov Moscow State University of Medicine and Dentistry, Moscow, Russia

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References:

Costi R, Himpens J, Bruyns J, Cadière GB. Totally laparoscopic transhiatal esophago-gastrectomy without thoracic or cervical access: The least invasive surgery for adenocarcinoma of the cardia? Surg Endosc. 2004;18(4):629-632. https://doi.org/10.1007/s00464-003-9053-5
Baccari P, Castoldi R, Bisagni P, Bissolotti G, Orsenigo E, Di Palo S, Casiraghi T, Carlucci M, Staudacher C. Minimally invasive esophagectomy for adenocarcinoma of the lower esophagus and the gastroesophageal junction. Tumori. 2005;4(3,Suppl.):S129.
Siewert JR, Stein HJ. Classification of adenocarcinoma of the oesophagogastric junction. Br J Surg. 1998;85(11):1457-1459.
Brierley JD, Gospodarowicz MK, Wittekid C, eds. TNM classification of malignant tumours. 8th ed. Oxford, UK: Wiley-Blackwell; 2017.
Straatman J, van der Wielen N, Nieuwenhuijzen GA, Rosman C, Roig J, Scheepers JJ, Cuesta MA, Luyer MD, van Berge Henegouwen MI, van Workum F, Gisbertz SS, van der Peet DL. Techniques and short-term outcomes for total minimally invasive Ivor Lewis esophageal resection in distal esophageal and gastroesophageal junction cancers: pooled data from six European centers. Surg Endosc. 2017;31(1):119-126. https://doi.org/10.1007/s00464-016-4938-2
Hong L, Zhang Y, Zhang H, Yang J, Zhao Q. The short-term outcome of three-field minimally invasive esophagectomy for Siewert type I esophagogastric junctional adenocarcinoma. Ann Thorac Surg. 2013;96(5):1826-1831. https://doi.org/10.1016/j.athoracsur.2013.06.058
Shiozaki A, Fujiwara H, Murayama Y, Komatsu S, Kuriu Y, Ikoma H, Nakanishi M, Ichikawa D, Okamoto K, Ochiai T, Kokuba Y, Otsuji E. Perioperative outcomes of esophagectomy preceded by the laparoscopic transhiatal approach for esophageal cancer. Dis Esophagus. 2014;27(5):470-478. https://doi.org/10.1111/j.1442-2050.2012.01439.x
Kauppila JH, Lagergren J. The surgical management of esophagogastric junctional cancer. Surg Oncol. 2016;25(4):394-400. https://doi.org/10.1016/j.suronc.2016.09.004
Okereke IC. Management of gastroesophageal junction tumors. Surg Clin North Am. 2017;97(2):265-275. https://doi.org/10.1016/j.suc.2016.11.004
Jezerskyte E, van Berge Henegouwen MI, Cuesta MA, Gisbertz SS. Gastro-esophageal junction cancers: what is the best minimally invasive approach? J Thorac Dis. 2017;9(Suppl.8):S751-S760. https://doi.org/10.21037/jtd.2017.06.56
van Workum F, Berkelmans GH, Klarenbeek BR, Nieuwenhuijzen GAP, Luyer MDP, Rosman C. McKeown or Ivor Lewis totally minimally invasive esophagectomy for cancer of the esophagus and gastroesophageal junction: systematic review and meta-analysis. J Thorac Dis. 2017;9(Suppl.8):S826-S833. https://doi.org/10.21037/jtd.2017.03.173
Zhai C, Liu Y, Li W, Xu T, Yang G, Lu H, Hu D. A comparison of short-term outcomes between Ivor-Lewis and McKeown minimally invasive esophagectomy. J Thorac Dis. 2015;7(12):2352-2358. https://doi.org/10.3978/j.issn.2072-1439.2015.12.15
Lin J, Kang M, Lin J, Chen S, Deng F, Han W, Lin R. Short-term efficacy comparison between Ivor-Lewis approach and McKeown approach in minimally invasive esophagectomy. Zhonghua Wei Chang Wai Ke Za Zhi. 2014;17(9):888-889.
Mu J, Yuan Z, Zhang B, Li N, Lyu F, Mao Y, et al. Comparative study of minimally invasive versus open esophagectomy for esophageal cancer in a single cancer center. Chin Med J (Engl). 2014;127(4):747-752.
Van Laethema J-L, Carneirob F, Ducreuxc M, Messmand H, Lordicke F, Ilson D.H, Allumg W.H, et al. The multidisciplinary management of gastro-oesophageal junction tumours. Dig Liver Dis. 2016;48(11):1283-1289. https://doi.org/10.1016/j.dld.2016.08.112
Smyth EC, Verheij M, Allum W, Cunningham D, Cervantes A, Arnold D. Gastric cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2016;27 (Suppl.5):38-49. https://doi.org/10.1093/annonc/mdw350
Huang CM, Lv CB, Lin JX, Chen QY, Zheng CH, Li P, et al. Laparoscopic-assisted versus open total gastrectomy for Siewert type II and III esophagogastric junction carcinoma: a propensity score-matched case-control study. Surg Endosc. 2017;31(9):3495-3503. https://doi.org/10.1007/s00464-016-5375-y
Zhou C, Zhang L, Wang H, Ma X, Shi B, Chen W, He J, Wang K, Liu P, Ren Y. Superiority of minimally invasive oesophagectomy in reducing in-hospital mortality of patients with resectable oesophageal cancer: a metaanalysis. PLoS One. 2015;10(7):e0132889. https://doi.org/10.1371/journal.pone.0132889
Sugita S, Kinoshita T, Kaito A, Watanabe M, Sunagawa H. Short-term outcomes after laparoscopic versus open transhiatal resection of Siewert type II adenocarcinoma of the esophagogastric junction. Surg Endosc. 2017;32(1):383-390. https://doi.org/10.1007/s00464-017-5687-6
Inokuchi M, Otsuki S, Ogawa N, Tanioka T, Okuno K, Gokita K, Kawano T, Kojima K. Postoperative complications of laparoscopic total gastrectomy versus open total gastrectomy for gastric cancer in a metaanalysis of high-quality case-controlled studies. Gastroenterol Res Pract. 2016;2617903. https://doi.org/10.1155/2016/2617903
Straatman J, van der Wielen N, Cuesta MA, de Lange-de Klerk ES, Jansma EP, van der Peet DL. Minimally invasive versus open total gastrectomy for gastric cancer: a systematic review and metaanalysis of short-term outcomes and completeness of resection. World J Surg. 2016;40(1):148-157. https://doi.org/10.1007/s00268-015-3223-1
Giacopuzzi S, Bencivenga M, Weindelmayer J, Verlato G, de Manzoni G. Western strategy for EGJ carcinoma. Gastric Cancer. 2017;20(Suppl.1):60-68. https://doi.org/10.1007/s10120-016-0685-2
Zhang WH, Chen XZ, Liu K, Anil K, Yang K, Chen JP, Zhou ZG, Hu JK. Comparison of the clinicopathological characteristics and the survival outcomes between the Siewert type II/III adenocarcinomas. Med Oncol. 2014;31(8):116. https://doi.org/10.1007/s12032-014-0116-3
Parry K, Haverkamp L, Bruijnen RC, Siersema PD, Ruurda JP, van Hillegersberg R. Surgical treatment of adenocarcinomas of the gastro-esophageal junction. Ann Surg Oncol. 2015;22(2):597-603. https://doi.org/10.1245/s10434-014-4047-1
Zheng Z, Cai J, Yin J, Zhang J, Zhang ZT, Wang KL. Transthoracic versus abdominal-transhiatal resection for treating Siewert type II/III adenocarcinoma of the esophagogastric junction: a meta-analysis. Int J Clin Exp Med. 2015;8(10):17167-17182.
Mullen JT, Kwak EL, Hong TS. What’s the best way to treat GE junction tumors? Approach Like Gastric Cancer. Ann Surg Oncol. 2016;23(12):3780-3785. https://doi.org/10.1245/s10434-016-5426-6
Hosoda K, Yamashita K, Moriya H, Mieno H, Watanabe M. Optimal treatment for Siewert type II and III adenocarcinoma of the esophagogastric junction: A retrospective cohort study with long-term follow-up. World J Gastroenterol. 2017;23(15):2723-2730. https://doi.org/10.3748/wjg.v23.i15.2723
Blank S, Schmidt T, Heger P, Strowitzki MJ, Sisic L, Heger U, Nienhueser H, Haag GM, Bruckner T, Mihaljevic AL, Ott K, Büchler MW, Ulrich A. Surgical strategies in true adenocarcinoma of the esophagogastric junction (AEG II): thoracoabdominal or abdominal approach? Gastric Cancer. 2018;21(2):303-314. https://doi.org/10.1007/s10120-017-0746-1
Zhou J, Wang H, Niu Z, Chen D, Wang D, Lv L, Li Y, Zhang J, Cao S, Shen Y, Zhou Y. Comparisons of clinical outcomes and prognoses in patients with gastroesophageal junction adenocarcinoma, by transthoracic and transabdominal hiatal approaches: A Teaching Hospital Retrospective Cohort Study. Medicine(Baltimore). 2015;94(50):e2277. https://doi.org/10.1097/md.0000000000002277
Kneuertz PJ, Hofstetter WL, Chiang YJ, Das P, Blum M, Elimova E, Mansfield P, Ajani J, Badgwell B. Long-term survival in patients with gastroesophageal junction cancer treated with preoperative therapy: do thoracic and abdominal approaches differ? Ann Surg Oncol. 2016;23(2):626-632. https://doi.org/10.1245/s10434-015-4898-0
Zhou D, Liu QX, Deng XF, Min JX, Dai JG. Comparison of two different mechanical esophagogastric anastomosis in esophageal cancer patients: a metaanalysis. J Cardiothorac Surg. 2015;10:67. https://doi.org/10.1186/s13019-015-0271-4
Okabe H, Tsunoda S, Tanaka E, Hisamori S, Kawada H, Sakai Y. Is laparoscopic total gastrectomy a safe operation? A review of various anastomotic techniques and their outcomes. Surg Today. 2015;45(5):549-558. https://doi.org/10.1007/s00595-014-0901-9
Kawamura H, Ohno Y, Ichikawa N, Yoshida T, Homma S, Takahashi M, Taketomi A. Anastomotic complications after laparoscopic total gastrectomy with esophagojejunostomy constructed by circular stapler (OrVil) versus linear stapler (overlap method). Surg Endosc. 2017;31(12):5175-5182. https://doi.org/10.1007/s00464-017-5584-z
Umemura A, Koeda K, Sasaki A, Fujiwara H, Kimura Y, Iwaya T, Akiyama Y, Wakabayashi G. Totally laparoscopic total gastrectomy for gastric cancer: literature review and comparison of the procedure of esophagojejunostomy. Asian J Surg. 2015;38(2):102-112. https://doi.org/10.1016/j.asjsur.2014.09.006
Liu QX, Qiu Y, Deng XF, Min JX, Dai JG. Comparison of outcomes following end-to-end hand-sewn and mechanical oesophagogastric anastomosis after oesophagectomy for carcinoma: a prospective randomized controlled trial. Eur J Cardiothorac Surg. 2015;47(3):e118-123. https://doi.org/10.1093/ejcts/ezu457
Zhang YS, Gao BR, Wang HJ, Su YF, Yang YZ, Zhang JH, Wang C. Comparison of anastomotic leakage and stricture formation following layered and stapler oesophagogastric anastomosis for cancer: a prospective randomized controlled trial. J Int Med Res. 2010;38(1):227-233. https://doi.org/10.1177/147323001003800127
Wang Q, He XR, Shi CH, Tian JH, Jiang L, He SL, Yang KH. Hand-sewn versus stapled esophagogastric anastomosis in the neck: a systematic review and meta-analysis of randomized controlled trials. Indian J Surg. 2015;77(2):133-140. https://doi.org/10.1007/s12262-013-0984-3
Honda M, Kuriyama A, Noma H, Nunobe S, Furukawa TA. Hand-sewn versus mechanical esophagogastric anastomosis after esophagectomy: a systematic review and metaanalysis. Ann Surg. 2013;257(2):238-248. https://doi.org/10.1097/sla.0b013e31826d4723
Castro PM, Ribeiro FP, Rocha Ade F, Mazzurana M, Alvarez GA. Hand-sewn versus stapler esophagogastric anastomosis after esophageal ressection: systematic review and metaanalysis. Arq Bras Cir Dig. 2014;27(3):216-221. https://doi.org/10.1590/s0102-67202014000300014
Harustiak T, Pazdro A, Snajdauf M, Stolz A, Lischke R. Anastomotic leak and stricture after hand-sewn versus linear-stapled intrathoracic oesophagogastric anastomosis: single-centre analysis of 415 oesophagectomies. Eur J Cardiothorac Surg. 2016;49(6):1650-1659. https://doi.org/10.1093/ejcts/ezv395
Deng XF, Liu QX, Zhou D, Min JX, Dai JG. Hand-sewn vs linearly stapled esophagogastric anastomosis for esophageal cancer: a metaanalysis. World J Gastroenterol. 2015;21(15):4757-4764. https://doi.org/10.3748/wjg.v21.i15.4757
Mishra PK, Shah H, Gupta N, Varshney V, Patil NS, Jain A, Saluja SS. Stapled versus hand-sewn cervical esophagogastric anastomosis in patients undergoing esophagectomy: A Retrospective Cohort Study. Ann Med Surg (Lond). 2016;5:118-124. https://doi.org/10.1016/j.amsu.2015.12.063
Saluja SS, Ray S, Pal S, Sanyal S, Agrawal N, Dash NR, Sahni P, Chattopadhyay TK. Randomized trial comparing side-to-side stapled and hand-sewn esophagogastric anastomosis in neck. J Gastrointest Surg. 2012;16(7):1287-1295. https://doi.org/10.1007/s11605-012-1885-7
Nederlof N, Tilanus HW, Tran TC, Hop WC, Wijnhoven BP, de Jonge J. End-to-end versus end-to-side esophagogastrostomy after esophageal cancer resection: a prospective randomized study. Ann Surg. 2011;254(2):226-233. https://doi.org/10.1097/sla.0b013e31822676a9
Haverkamp L, van der Sluis PC, Verhage RJ, Siersema PD, Ruurda JP, van Hillegersberg R. End-to-end cervical esophagogastric anastomoses are associated with a higher number of strictures compared with end-to-side anastomoses. J Gastrointest Surg. 2013;17(5):872-876. https://doi.org/10.1007/s11605-013-2159-8
Nakata K, Nagai E, Ohuchida K, Nakamura K, Tanaka M. Outcomes of cervical end-to-side triangulating esophagogastric anastomosis with minimally invasive esophagectomy. World J Surg. 2015;39(5):1099-1104. https://doi.org/10.1007/s00268-014-2925-0
Xin H, Han Z. Esophagectomy and cervical side-to-side stapled esophagogastric anastomosis. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2009;34(2):148-151.
Levchenko EV, Kanaev SV, Tyuryaeva EI, Dvoreckii SYu, Shcherbakov AM, Komarov IV, Khandogin NV, Ivantsov AO, Shabaturov LYu. Results of complex treatment of patients with thoracic esophageal cancer. Voprosy onkologii. 2016;62(2):302-309. (In Russ.)
Mariiko VA, Nechai VC, Kuznetsov VV, Dorofeev DA. Videothoracoscopic esophagoectomy in patients with cardioesophageal cancer. Eksperimental’naya khirurgiya. 2006;12(4):3-4. (In Russ.)
Khat’kov IE, Izrailov RE, Domrachev SA, Kononets PV, Vasnev OS, Koshkin MA. Thoracolaparoscopic simultaneous operations on esophagus. Zhurnal im. N.I.Pirogova. 2014;10:45-51. (In Russ.)