The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-0604

  • © 1998-2025
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Niushko K.M.

FGBU "Moskovskiĭ nauchno-issledovatel'skiĭ onkologicheskiĭ institut im. P.A. Gertsena" Minzdravsotsrazvitiia Rossii

Alekseev B.Ia.

FGBU "Moskovskiĭ nauchno-issledovatel'skiĭ onkologicheskiĭ institut im. P.A. Gertsena" Minzdrava Rossii

Krasheninnikov A.A.

FGBU «Moskovskiĭ nauchno-issledovatelskiĭ onkologicheskiĭ institut im. P.A. Gertsena» Minzdrava Rossii

Vorob'ev N.V.

FGBU "Moskovskiĭ nauchno-issledovatel'skiĭ onkologicheskiĭ institut im P.A. Gertsena"

Safronova E.Yu.

P.A. Herzen Moscow Oncology Research Institute, Branch, National Medical Radiology Research Center, Ministry of Health of Russia, Moscow, Russia

Kalpinskiĭ A.S.

FGBU "Moskovskiĭ nauchno-issledovatel'skiĭ onkologicheskiĭ institut im. P.A. Gertsena" Minzdrava Rossiii

Sergienko S.A.

P.A. Herzen Moscow Oncology Research Institute, Branch, National Medical Radiology Research Center, Ministry of Health of Russia, Moscow, Russia

Taraki I.A.

P.A. Herzen Moscow Oncology Research Institute, Branch, National Medical Radiology Research Center, Ministry of Health of Russia, Moscow, Russia

Temirgereev M.Z.

P.A. Herzen Moscow Oncology Research Institute, Branch, National Medical Radiology Research Center, Ministry of Health of Russia, Moscow, Russia

Kaprin A.D.

FGBU "Moskovskiĭ nauchno-issledovatel'skiĭ onkologicheskiĭ institut im. P.A. Gertsena" Minzdrava Rossii

Surgical treatment in patients with localized and locally advanced prostate cancer: results of a monocentric study

Authors:

Niushko K.M., Alekseev B.Ia., Krasheninnikov A.A., Vorob'ev N.V., Safronova E.Yu., Kalpinskiĭ A.S., Sergienko S.A., Taraki I.A., Temirgereev M.Z., Kaprin A.D.

More about the authors

Journal: P.A. Herzen Journal of Oncology. 2018;7(1): 4‑13

DOI: 10.17116/onkolog2018714-13

Views: 878

Downloaded: 10

Download PDF (RU)
Contact the author
Table of contents

To cite this article:

Niushko KM, Alekseev BIa, Krasheninnikov AA, et al. . Surgical treatment in patients with localized and locally advanced prostate cancer: results of a monocentric study. P.A. Herzen Journal of Oncology. 2018;7(1):4‑13. (In Russ.)
https://doi.org/10.17116/onkolog2018714-13

МСФ на ЯМ
Close metadata
Recommended articles:
Patient-centered approach to asse­ssing tole­rability of anti­tumor treatment for oral cavity and oropharyngeal cancer. P.A. Herzen Journal of Onco­logy. 2024;(2):21-26
Mini­mally inva­sive surgical treatment of extramedullary tumors at the level of craniovertebral junction: expe­rience of the Burdenko Neurosurgical Center. Burdenko's Journal of Neurosurgery. 2024;(2):39-46
Infi­ltrating Endo­metriosis of the Distal Part of Round Uterine Liga­ment and It’s Asso­ciation with Nuck’s Dive­rticulum (Literature Review and Case Report). Russian Journal of Human Reproduction. 2024;(2):112-121
Surgical technique for aspi­ration of soft lens nucleus with preoperative femtosecond laser-assisted fragmentation. Russian Annals of Ophthalmology. 2024;(2-2):109-115
Surgical treatment of a patient with syphilitic aortitis. Piro­gov Russian Journal of Surgery. 2024;(5):123-128
Surgical treatment of idiopathic pulmonary artery aneurysm. Russian Journal of Cardiology and Cardiovascular Surgery. 2024;(3):321-328
Thoracoscopic rese­ction of recu­rrent atypically loca­ted para­thyroid adenoma of ante­rior mediastinum in a patient with hype­rparathyroidism unde­rgoing renal replacement therapy. Piro­gov Russian Journal of Surgery. 2024;(6):81-87
Surgical treatment of chondromyxoid fibroma of ribs via thoracoabdominal access. Piro­gov Russian Journal of Surgery. 2024;(6):94-99
Predicting the risk of decreased ovarian rese­rve after surgical treatment of patients with deep infi­ltrative endo­metriosis using arti­ficial inte­lligence. Russian Bulletin of Obstetrician-Gynecologist. 2024;(3):92-102
Modern treatment of perianal fistulas following Crohn’s disease. Rege­nerative Biotechnologies, Preventive, Digi­tal and Predictive Medi­cine. 2024;(2):49-56

Objective — to assess the immediate and long-term results of surgical treatment in patients with prostate cancer (PC). Material and methods. The Department of Urologic Oncology, P.A. Herzen Moscow Oncology Research Institute, retrospectively analyzed the database of 1846 patients with PC who had received surgical treatment in 1998 to 2016. It also analyzed preoperative patient characteristics, pathology data, intra- and postoperative complications, as well as the long-term functional and oncological results of surgical treatment. There was a tendency to increase the number of surgically treated patients with PC who had a high risk for disease progression and unfavorable prognostic factors. Conclusion. The accumulation of surgical experience can substantially optimize treatment results in patients with PC and reduce the incidence of complications. The advantages of surgical treatment include accurate staging and detection of adverse pathological factors, which allows the elaboration of a rational treatment policy. It is advisable to consider adjuvant therapy for patients with unfavorable postoperative prognostic factors (the presence of lymphogenic metastases, including those with extracapsular invasion) in order to improve survival rates.

Keywords:

prostate cancer
surgical treatment
adjuvant therapy
survival

Authors:

Niushko K.M.

FGBU "Moskovskiĭ nauchno-issledovatel'skiĭ onkologicheskiĭ institut im. P.A. Gertsena" Minzdravsotsrazvitiia Rossii

Alekseev B.Ia.

FGBU "Moskovskiĭ nauchno-issledovatel'skiĭ onkologicheskiĭ institut im. P.A. Gertsena" Minzdrava Rossii

Krasheninnikov A.A.

FGBU «Moskovskiĭ nauchno-issledovatelskiĭ onkologicheskiĭ institut im. P.A. Gertsena» Minzdrava Rossii

Vorob'ev N.V.

FGBU "Moskovskiĭ nauchno-issledovatel'skiĭ onkologicheskiĭ institut im P.A. Gertsena"

Safronova E.Yu.

P.A. Herzen Moscow Oncology Research Institute, Branch, National Medical Radiology Research Center, Ministry of Health of Russia, Moscow, Russia

Kalpinskiĭ A.S.

FGBU "Moskovskiĭ nauchno-issledovatel'skiĭ onkologicheskiĭ institut im. P.A. Gertsena" Minzdrava Rossiii

Sergienko S.A.

P.A. Herzen Moscow Oncology Research Institute, Branch, National Medical Radiology Research Center, Ministry of Health of Russia, Moscow, Russia

Taraki I.A.

P.A. Herzen Moscow Oncology Research Institute, Branch, National Medical Radiology Research Center, Ministry of Health of Russia, Moscow, Russia

Temirgereev M.Z.

P.A. Herzen Moscow Oncology Research Institute, Branch, National Medical Radiology Research Center, Ministry of Health of Russia, Moscow, Russia

Kaprin A.D.

FGBU "Moskovskiĭ nauchno-issledovatel'skiĭ onkologicheskiĭ institut im. P.A. Gertsena" Minzdrava Rossii

List of references:

  1. Kaprin AD, Starinskii VV, Petrova GV, eds. Zlokachestvennye novoobrazovaniya v Rossii v 2015 (zabolevaemost’ i smertnost’). Moscow: MNIOI im. P.A. Gertsena — filial FGBU «NMIRTs» Minzdrava Rossii; 2017. (In Russ.)
  2. De Angelis R, Sant M, Coleman MP, Francisci S, Baili P, Pierannunzio D, Trama A, Visser O, Brenner H, Ardanaz E, Bielska-Lasota M, Engholm G, Nennecke A, Siesling S, Berrino F, Capocaccia R; EUROCARE-5 Working Group. Cancer survival in Europe 1999-2007 by country and age: results of EUROCARE-5-a population-based study. Lancet Oncol. 2014;15(1):23-34. https://doi.org/10.1016/S1470-2045(13)70546-1
  3. Jansson KF, Akre O, Garmo H, Bill-Axelson A, Adolfsson J, Stattin P, Bratt O. Concordance of tumor differentiation among brothers with prostate cancer. Eur Urol. 2012;62(4):656-661. https://doi.org/10.1016/j.eururo.2012.02.032
  4. Bill-Axelson A, Holmberg L, Garmo H, Rider JR, Taari K, Busch C, Nordling S, Häggman M, Andersson SO, Spångberg A, Andrén O, Palmgren J, Steineck G, Adami HO, Johansson JE. Radical prostatectomy or watchful waiting in early prostate cancer. N Engl J Med. 2014;370(10):932-942. https://doi.org/10.1056/NEJMoa1311593
  5. Sakr WA, Haas GP, Cassin BF, Pontes JE, Crissman JD. The frequency of carcinoma and intraepithelial neoplasia of the prostate in young male patients. J Urol. 1993;150(2,Pt1):379-385. https://doi.org/10.1016/S0022-5347(17)35487-3
  6. Dahm P, Yang B, Salmen C, Moul J, Gan T. Radical perineal prostatectomy for the treatment of localized prostate cancer in morbidly obese patients. J Urol. 2005;174(1):131-134. https://doi.org/10.1097/01.ju.0000161593.29525.e2
  7. Paiva C, Andreoni C, Cunha G, Khalil W, Ortiz V. Differences among patients undergoing perineal or retropubic radical prostatectomy in pain and perioperative variables: a prospective study. BJU Int. 2009;104(9):1219-1226. https://doi.org/10.1111/j.1464-410x.2009.08551.x
  8. Fichtner J, Gillitzer R, Melchior S. Perineal complications following radical perineal prostatectomy. Aktuelle Urol. 2003;34(4):223-225. https://doi.org/10.1055/s-2003-41599
  9. Lassen PM, Kearse WS. Rectal injuries during radical perineal prostatectomy. Urology. 1995;45:266-269. https://doi.org/10.1016/0090-4295(95)80016-6
  10. Alekseev BYa, Nyushko KM, Kalpinskii AS, Krasheninnikov AA, Vorob’ev NV, Sergienko SA, Kaprin AD. Radical perineal prostatectomy in patients with prostate cancer: methodological aspects and results. Onkologiya. Zhurnal im. P.A. Gertsena. 2016;5(1):5-11. (In Russ.) https://doi.org/10.17116/onkolog2016515-11
  11. Jansson KF, Akre O, Garmo H, Bill-Axelson A, Adolfsson J, Stattin P, Bratt O. Oncologic outcome after laparoscopic radical prostatectomy: 10 years of experience. Eur Urol. 2009;55(5):1014-1019. https://doi.org/10.1016/j.eururo.2008.10.036
  12. Magheli A, Gonzalgo ML, Su LM, Guzzo TJ, Netto G, Humphreys EB, Han M, Partin AW, Pavlovich CP. Impact of surgical technique (open vs laparoscopic vs robotic-assisted) on pathological and biochemical outcomes following radical prostatectomy: an analysis using propensity score matching. BJU Int. 2011;107(12):1956-1962. https://doi.org/10.1111/j.1464-410X.2010.09795.x
  13. Ramsay C, Pickard R, Robertson C, Close A, Vale L, Armstrong N, Barocas DA, Eden CG, Fraser C, Gurung T, Jenkinson D, Jia X, Lam TB, Mowatt G, Neal DE, Robinson MC, Royle J, Rushton SP, Sharma P, Shirley MD, Soomro N. Systematic review and economic modelling of the relative clinical benefit and cost-effectiveness of laparoscopic surgery and robotic surgery for removal of the prostate in men with localised prostate cancer. Health Technol Assess. 2012;16(41):1-313. https://doi.org/10.3310/hta16410
  14. Prostate cancer: diagnosis and treatment. Cardiff (UK): National Collaborating Centre for Cancer (UK); 2014 Jan. NICE Clinical Guidelines, No. 175. https://www.ncbi.nlm.nih.gov/books/NBK247469/?report=reader
  15. Asimakopoulos AD, Pereira Fraga CT, Annino F, Pasqualetti P, Calado AA, Mugnier C. Randomized comparison between laparoscopic and robot-assisted nerve-sparing radical prostatectomy. J Sex Med. 2011;8(5):1503-1512. https://doi.org/10.1111/j.1743-6109.2011.02215.x
  16. Berge V, Berg RE, Hoff JR, Wessel N, Diep LM, Karlsen SJ, Eri LM. A prospective study of transition from laparoscopic to robot-assisted radical prostatectomy: quality of life outcomes after 36-month follow-up. Urology. 2013;81(4):781-786. https://doi.org/10.1016/j.urology.2013.01.017
  17. Cristian Fiori, Ivano Morra, Francesca Ragni, Susanna Grande, Marco Lucci Chiarissi, Fabrizio Mele, Massimiliano Poggio, Francesco Porpiglia. 1130 pure versus robot-assisted laparoscopic prostatectomy single center, single surgeon experience. J Urol. 2012;187(4,Suppl.):e458. https://doi.org/10.1016/j.juro.2012.02.1239
  18. Wolanski P, Chabert C, Jones L, Mullavey T, Walsh S, Gianduzzo T. Preliminary results of robot-assisted laparoscopic radical prostatectomy (RALP) after fellowship training and experience in laparoscopic radical prostatectomy (LRP). BJU Int. 2012;110(Suppl.4):64-70. https://doi.org/10.1111/j.1464-410X.2012.11479.x
  19. Hoskin PJ, Rojas AM, Ostler PJ, Hughes R, Lowe GJ, Bryant L. Quality of life after radical radiotherapy for prostate cancer: longitudinal study from a randomised trial of external beam radiotherapy alone or in combination with high dose rate brachytherapy. Clin Oncol. 2013;25(5):321-327. https://doi.org/10.1016/j.clon.2013.01.001
  20. Joseph JV, Vicente I, Madeb R, Erturk E, Patel HR. Robot-assisted vs pure laparoscopic radical prostatectomy: are there any differences? BJU Int. 2005;96(1):39-42. https://doi.org/10.1111/j.1464-410X.2005.05563.x
  21. Willis DL, Gonzalgo ML, Brotzman M, Feng Z, Trock B, Su LM. Comparison of outcomes between pure laparoscopic vs robot-assisted laparoscopic radical prostatectomy: a study of comparative effectiveness based upon validated quality of life outcomes. BJU Int. 2012;109(6):898-905. https://doi.org/10.1111/j.1464-410X.2011.10551.x
  22. Meng MV, Elkin EP, Latini DM, Duchane J, Carroll PR. Treatment of patients with high risk localized prostate cancer: results from cancer of the prostate strategic urological research endeavor (CaPSURE). J. Urol. 2005;173(5):1557-1561. https://doi.org/10.1097/01.ju.0000154610.81916.81
  23. Cooperberg MR, Carroll PR. Trends in management for patients with localized prostate cancer. 1990—2013. JAMA. 2015;314(1):80-2. https://doi.org/10.1001/jama.2015.6036
  24. Freedland SJ, Partin AW, Humphreys EB, Mangold LA, Walsh PC. Radical prostatectomy for clinical stage T3a disease. Cancer. 2007;109(7):1273-1278. https://doi.org/10.1002/cncr.22544
  25. Akre O, Garmo H, Adolfsson J, Lambe M, Bratt O, Stattin P. Mortality among men with locally advanced prostate cancer managed with noncurative intent: a nationwide study in PCBaSe Sweden. Eur Urol. 2011;60(3):554-563. https://doi.org/10.1016/j.eururo.2011.05.047
  26. Ward JF, Slezak JM, Blute ML, Bergstralh EJ, Zincke H. Radical prostatectomy for clinically advanced (cT3) prostate cancer since the advent of prostate-specific antigen testing: 15-year outcome. BJU Int. 2005;95(6):751-756. https://doi.org/10.1111/j.1464-410X.2005.05394.x
  27. Yossepowitch O, Eggener SE, Serio AM, Carver BS, Bianco FJ Jr, Scardino PT, Eastham JA. Secondary therapy, metastatic progression, and cancer-specific mortality in men with clinically high-risk prostate cancer treated with radical prostatectomy. Eur. Urol. 2008;53(5):950-959. https://doi.org/10.1016/j.eururo.2007.10.008
  28. Stephenson AJ, Kattan MW, Eastham JA, Bianco FJ Jr, Yossepowitch O, Vickers AJ, Klein EA, Wood DP, Scardino PT. Prostate cancer-specific mortality after radical prostatectomy for patients treated in the prostate-specific antigen era. J Clin Oncol. 2009;27(26):4300-4305. https://doi.org/10.1200/JCO.2008.18.2501
  29. Mitchell CR, Boorjian SA, Umbreit EC, Rangel LJ, Carlson RE, Karnes RJ. 20-year survival after radical prostatectomy as initial treatment for cT3 prostate cancer. BJU Int. 2012;110(11):1709-1713. https://doi.org/10.1111/j.1464-410X.2012.11372.x
  30. Briganti A, Karnes RJ, Gandaglia G, Spahn M, Gontero P, Tosco L. Natural history of surgically treated high-risk prostate cancer. Urol Oncol. 2015;33(4):163.e7-13. https://doi.org/10.1016/j.urolonc.2014.11.018

Close metadata

Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Contact us
If you have any questions, complaints or suggestions, please use this feedback form.
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.
Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.