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Kit O.I.

National Medical Research Center of Oncology

Gevorkyan Yu.A.

National Medical Research Center of Oncology

Karachun A.M.

N.N. Petrov National Medical Research Center for Oncology

Soldatkina N.V.

National Medical Research Center of Oncology

Bondarenko O.K.

National Medical Research Center of Oncology

Kolesnikov V.E.

National Medical Research Center of Oncology

D2 and D3 lymph node dissection for colon cancer

Authors:

Kit O.I., Gevorkyan Yu.A., Karachun A.M., Soldatkina N.V., Bondarenko O.K., Kolesnikov V.E.

More about the authors

Journal: Pirogov Russian Journal of Surgery. 2024;(7): 25‑35

DOI: 10.17116/hirurgia202407125

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Table of contents

To cite this article:

Kit OI, Gevorkyan YuA, Karachun AM, Soldatkina NV, Bondarenko OK, Kolesnikov VE. D2 and D3 lymph node dissection for colon cancer. Pirogov Russian Journal of Surgery. 2024;(7):25‑35. (In Russ.)
https://doi.org/10.17116/hirurgia202407125

Подписка 2025 (Pirogov Russian Journal of Surgery)
МСФ на ЯМ
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OBJECTIVE

To evaluate surgical and oncological results of standard and extended lymph node dissection (D2 and D3) in patients with colon cancer.

MATERIAL AND METHODS

We analyzed treatment outcomes in 74 patients with colon cancer stage T1-4aN0-2M0 who underwent right- and left-sided hemicolectomy, resection of sigmoid colon with standard and extended lymph node dissection (D2 and D3).

RESULTS

Surgical approach and level of D3 lymph node dissection did not increase intra- and postoperative morbidity. Laparoscopic interventions were followed by significantly lower intraoperative blood loss and earlier gas discharge. Metastatic lesion of apical lymph nodes was observed in 5 out of 36 patients who underwent D3 lymph node dissection (13.8%), and metastases in regional lymph nodes rN1-2 were found in all these patients. Overall 5-year survival was 86%. Disease-free and overall 5-year survival were similar after D2 and D3 lymph node dissection.

CONCLUSION

D3 lymph node dissection is safe for colon cancer. Metastatic lesions of apical lymph nodes during D3 lymph node dissection were detected only in patients with lesions of regional lymph nodes (rN1-2). Disease-free and overall 5-year survival were similar after D2 and D3 lymph node dissection.

Keywords:

colon cancer
mesocolonectomy
D2 lymph node dissection
D3 lymph node dissection
survival

Authors:

Kit O.I.

National Medical Research Center of Oncology

Gevorkyan Yu.A.

National Medical Research Center of Oncology

Karachun A.M.

N.N. Petrov National Medical Research Center for Oncology

Soldatkina N.V.

National Medical Research Center of Oncology

Bondarenko O.K.

National Medical Research Center of Oncology

Kolesnikov V.E.

National Medical Research Center of Oncology

Received:

18.12.2023

Accepted:

19.01.2024

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