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Khomyakov V.M.

Military medical unit, Golytsino, Moscow region, Russia, P.A. Gertsen Moscow scientific and research oncologic institute, National medical research center of radiology trust, Moscow, Russia

Ryabov A.B.

Hertsen Moscow Oncology Research Center, Moscow, Russia

Bolotina L.V.

FGBU "Moskovskiĭ nauchno-issledovatel'skiĭ onkologicheskiĭ institut im. P.A. Gertsena" Minzdravsotsrazvitiia Rossii

Sobolev D.D.

FGBU "Moskovskiĭ nauchno-issledovatel'skiĭ onkologicheskiĭ institut im. P.A. Gertsena" Minzdrava Rossii

Utkina A.B.

P.A. Herzen Moscow Oncology Research Institute, Branch, P.A. Herzen Federal Medical Research Center, Ministry of Health of Russia, Moscow

Kuznetsova O.S.

P.A. Herzen Moscow Oncology Research Institute, Branch, National Medical Radiology Research Center, Ministry of Health of the Russian Federation, Moscow, Russia

Treatment of patients with gastric cancer and peritoneal carcinomatosis: current views and perspectives

Authors:

Khomyakov V.M., Ryabov A.B., Bolotina L.V., Sobolev D.D., Utkina A.B., Kuznetsova O.S.

More about the authors

Journal: P.A. Herzen Journal of Oncology. 2017;6(6): 4‑13

DOI: 10.17116/onkolog2017664-13

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Table of contents

TREATMENT OF PATIENTS WITH GASTRIC CANCER AND PERITONEAL CARCINOMATOSIS: CURRENT VIEWS AND PERSPECTIVES
TREATMENT OF PATIENTS WITH GASTRIC CANCER AND PERITONEAL CARCINOMATOSIS: CURRENT VIEWS AND PERSPECTIVES

To cite this article:

Khomyakov VM, Ryabov AB, Bolotina LV, Sobolev DD, Utkina AB, Kuznetsova OS. Treatment of patients with gastric cancer and peritoneal carcinomatosis: current views and perspectives. P.A. Herzen Journal of Oncology. 2017;6(6):4‑13. (In Russ.)
https://doi.org/10.17116/onkolog2017664-13

Подписка 2026 Онкология. Журнал им. П.А. Герцена (P.A. Herzen Journal of Oncology)
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Abstract:

Peritoneal carcinomatosis (PC) is one of the most common and unfavorable types of metastasis of primary gastric cancer (GC) and 10—46% of patients can develop peritoneal recurrence after radical surgical treatment. The mainstay of treatment for metastatic GC is systemic chemotherapy; however, the frequency of an objective response does not exceed 14—25% with a median survival of 8-10 months. The paper reviews current GC treatments (cytoreductive surgery, intraoperative hyperthermic intraperitoneal chemotherapy (HIPEC), neoadjuvant intraperitoneal and systemic chemotherapy (NIPS), and pressurized intraperitoneal aerosol chemotherapy (PIPAC)). It analyzes the results of large-scale randomized studies and meta-analyses, as well as the unique experience of the P.A. Herzen Moscow Oncology Research Institute in using different intraperitoneal chemotherapies (HIPEC, PIPAC) with an assessment of their advantages and limitations. The current treatments, including different intraperitoneal chemotherapies, can substantially extend the life of GC patients with PC, by strictly selecting patients and implementing treatment protocols in specialized centers.

Keywords:

gastric cancer
dissemination
peritoneal carcinomatosis
cytoreductive surgery
intraoperative hyperthermic intraperitoneal chemotherapy
pressurized intraperitoneal aerosol chemotherapy

Authors:

Khomyakov V.M.

Military medical unit, Golytsino, Moscow region, Russia, P.A. Gertsen Moscow scientific and research oncologic institute, National medical research center of radiology trust, Moscow, Russia

Ryabov A.B.

Hertsen Moscow Oncology Research Center, Moscow, Russia

Bolotina L.V.

FGBU "Moskovskiĭ nauchno-issledovatel'skiĭ onkologicheskiĭ institut im. P.A. Gertsena" Minzdravsotsrazvitiia Rossii

Sobolev D.D.

FGBU "Moskovskiĭ nauchno-issledovatel'skiĭ onkologicheskiĭ institut im. P.A. Gertsena" Minzdrava Rossii

Utkina A.B.

P.A. Herzen Moscow Oncology Research Institute, Branch, P.A. Herzen Federal Medical Research Center, Ministry of Health of Russia, Moscow

Kuznetsova O.S.

P.A. Herzen Moscow Oncology Research Institute, Branch, National Medical Radiology Research Center, Ministry of Health of the Russian Federation, Moscow, Russia

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