The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-4329
+8 800 250-18-12
  • (toll-free number for subscriptions)
    Mon-Fri from 10 a.m. to 6 p.m.

  • © 1998-2026
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Ermoshchenkova M.V.

FGBU "Moskovskiĭ nauchno-issledovatel'skiĭ onkologicheskiĭ institut im. P.A. Gertsena" Minzdravsotsrazvitiia Rossii

Zikiryakhodzhaev A.D.

P.A. Herzen Moscow Oncology Research Institute, Ministry of Health of Russia, Moscow

Chissov V.I.

Moskovskiĭ nauchno-issledovatel'skiĭ onkologicheskiĭ institut im. P.A. Gertsena Rosmedtekhnologiĭ, Moskva

Shirokikh I.M.

Peoples’ Friendship University of Russia, Moscow, Russia

Tukmakov A.Yu.

Department of Oncology and Radiotherapy, Institute of Postgraduate Education, I.M. Sechenov First Moscow State Medical University, Moscow, Russia

Sukhot'ko A.S.

FGBU "Moskovskiĭ nauchno-issledovatel'skiĭ onkologicheskiĭ institut im. P.A. Gertsena" Minzdravsotsrazvitiia Rossii

Baichorov E.A.

Stavropol State Medical University, Stavropol, Russia

Reconstructive plastic surgery using biological and synthetic materials in patients with breast cancer

Authors:

Ermoshchenkova M.V., Zikiryakhodzhaev A.D., Chissov V.I., Shirokikh I.M., Tukmakov A.Yu., Sukhot'ko A.S., Baichorov E.A.

More about the authors

Journal: P.A. Herzen Journal of Oncology. 2017;6(4): 29‑37

DOI: 10.17116/onkolog20176429-37

Read: 1781 times

Download PDF (RU)
Contact the author
Table of contents

RECONSTRUCTIVE PLASTIC SURGERY USING BIOLOGICAL AND SYNTHETIC MATERIALS IN PATIENTS WITH BREAST CANCER
RECONSTRUCTIVE PLASTIC SURGERY USING BIOLOGICAL AND SYNTHETIC MATERIALS IN PATIENTS WITH BREAST CANCER

To cite this article:

Ermoshchenkova MV, Zikiryakhodzhaev AD, Chissov VI, Shirokikh IM, Tukmakov AYu, Sukhot'ko AS, Baichorov EA. Reconstructive plastic surgery using biological and synthetic materials in patients with breast cancer. P.A. Herzen Journal of Oncology. 2017;6(4):29‑37. (In Russ.)
https://doi.org/10.17116/onkolog20176429-37

Подписка 2026 Онкология. Журнал им. П.А. Герцена (P.A. Herzen Journal of Oncology)
МСФ на ЯМ
Использование инфографики авторами научных работ
Close metadata
Recommended articles:
Treatment outcomes of stage IIA–IIB breast cancer patients of hormone-positive HER2-negative subtype after neoadjuvant poly­chemotherapy depe­nding on Ki-67 levels. P.A. Herzen Journal of Onco­logy. 2025;(2):13-18
Hema­tological indi­cators of the systemic inflammatory response in the prognosis of lumi­nal HER2-negative breast cancer patients unde­rgoing surgery followed by adju­vant therapy. P.A. Herzen Journal of Onco­logy. 2025;(3):31-38
Hemo­stasis diso­rders during neoadjuvant therapy in patients with breast cancer. P.A. Herzen Journal of Onco­logy. 2025;(3):39-44
The effect of acetylamide synthetic peptide HLDF-6 on cell differentiation in breast cancer. Russian Journal of Archive of Pathology. 2025;(2):5-10
Repeated breast reco­nstruction after previous complications. Piro­gov Russian Journal of Surgery. 2025;(6):51-57
Causes of unsa­tisfactory postoperative outcomes in patients with hiatal hernia. Piro­gov Russian Journal of Surgery. 2025;(6):98-103
Guidelines for asse­ssing the quality of mammographic images. Russian Journal of Preventive Medi­cine. 2025;(6):21-32
Inci­dence of regional lymph node meta­stases in patients with early prognostically unfa­vorable mole­cular biological breast cancer. Piro­gov Russian Journal of Surgery. 2025;(7):11-15
Auto­logous fat transplantation into post-lymphadenectomy cavity for prevention of lymphorrhea after total mastectomy. Piro­gov Russian Journal of Surgery. 2025;(7):24-35
Simu­ltaneous reco­nstruction using endo­prosthesis and lower deepithelialized flap in prophylactic mastectomy. Plastic Surgery and Aesthetic Medi­cine. 2025;(2-2):16-24
Abstract:

Objective. To evaluate reconstructive plastic surgery using synthetic and biological materials in the rehabilitation of patients with breast cancer (BC). Subjects and methods. In 2014 to 2017, the P.A. Herzen Moscow Oncology Research Institute has performed 145 reconstructive operations using synthetic and biological materials in 115 patients (mean age 41.5 years) with BC. Stage 0 TisN0M0 BC was diagnosed in 11 (9.6%) patients, Stage I in 51 (44.4%), Stage IIA in 37 (32.2%), Stage IIB in 9 (7.8%), Stage IIIA in 3 (2.6%), Stage IIIB in 2 (1.7%), and Stage IIIC in 2 (1.7%). The volume of a silicone endoprosthesis ranged from 160 to 585 cm3. To strengthen the lower slope of the breast, titanium mesh implants were used in 12 patients, Parietex polyester mesh implants in 105, and a Permacol acellular dermal matrix (ADM) in 28. Results. In the ADM group, one patient developed skin flap necrosis. The development of long-standing small seromas in the central parts of a postoperative scar was noted in one patient. One case was found to develop skin reactions as obvious hyperemia during adjuvant polychemotherapy at 4 months after surgery using an endoprosthesis and ADM, which required medical treatment. In 2 (18%) cases, ADM and an implant were removed because of postoperative wound suppuration. In the ADM group, excellent, good, and poor cosmetic results were observed in 17 (70.8%), 5 (20.8%), and 2 (8.4%) cases, respectively. Conclusion. Biological and synthetic materials are an important addition to various breast reconstruction options. The value of the pinch-test is a criterion for selecting the material for strengthening the lower slope of the breast during subcutaneous or skin-sparing mastectomy for cancer with single-stage reconstruction with a silicone implant. When the pinch-test value is more than 0.5 cm, it is adequate to use as a synthetic implant and ADM. When that is less than 0.5 cm, preference should be given to ADM.

Keywords:

breast cancer
reconstructive plastic surgery
subcutaneous mastectomy
skin-sparing mastectomy
mesh implant
acellular dermal matrix

Authors:

Ermoshchenkova M.V.

FGBU "Moskovskiĭ nauchno-issledovatel'skiĭ onkologicheskiĭ institut im. P.A. Gertsena" Minzdravsotsrazvitiia Rossii

Zikiryakhodzhaev A.D.

P.A. Herzen Moscow Oncology Research Institute, Ministry of Health of Russia, Moscow

Chissov V.I.

Moskovskiĭ nauchno-issledovatel'skiĭ onkologicheskiĭ institut im. P.A. Gertsena Rosmedtekhnologiĭ, Moskva

Shirokikh I.M.

Peoples’ Friendship University of Russia, Moscow, Russia

Tukmakov A.Yu.

Department of Oncology and Radiotherapy, Institute of Postgraduate Education, I.M. Sechenov First Moscow State Medical University, Moscow, Russia

Sukhot'ko A.S.

FGBU "Moskovskiĭ nauchno-issledovatel'skiĭ onkologicheskiĭ institut im. P.A. Gertsena" Minzdravsotsrazvitiia Rossii

Baichorov E.A.

Stavropol State Medical University, Stavropol, Russia

Close metadata

References:

  1. Kaprin AD, Starinskii VV, Petrova GV, eds. Malignant neoplasms in Russia in 2014 (morbidity and mortality) [Zlokachestvennye novoobrazovaniya v Rossii v 2014 (zabolevaemost’ i smertnost’)]. Moscow: MNIOI im. P.A. Gertsena — filial FGBU NMIRTs Minzdrava Rossii; 2016. (In Russ.).
  2. Aseev AV. Plastic and reconstructive microsurgery in oncology. Klinicheskaya meditsina. 1993;(3):30-34. (In Russ.).
  3. Awan BA, Samargandi OA, Alghamdi HA, Sayegh AA, Hakeem YJ, Merdad L, Merdad AA. The desire to utilize postmastectomy breast reconstruction in Saudi Arabian women. Predictors and barriers. Saudi Med J. 2015;36(3):304-309. https://doi.org/10.15537/smj.2015.3.10688
  4. Morrow M, Li Y, Alderman AK, Jagsi R, Hamilton AS, Graff JJ, et al. Access to breast reconstruction after mastectomy and patient perspectives on reconstruction decision making. JAMA Surg. 2014;149(10):1015-1021. https://doi.org/10.1001/jamasurg.2014.548
  5. Reshetov IV, Chissov VI. Plastic and reconstructive microsurgery in oncology [Plasticheskaya i rekonstruktivnaya mikrokhirurgiya v onkologii]. Moscow; 2001. (In Russ.).
  6. Chalnot P, Michon J. Le dedoublement du sein restant. Ann Chir Plast. 1958;3:35.
  7. Semiglazov VF. Minimal breast cancer [Minimal’nyi rak molochnoi zhelezy]. Leningrad: Meditsina; 1992. (In Russ.).
  8. Sharova ON, Vasil’ev SA, Buikov VA, Vazhenin AV. Reconstruction of the breast as the most constructive mechanism of psychological protection in women after the radical treatment of breast cancer. Annaly plasticheskoi, rekonstruktivnoi i esteticheskoi khirurgii. 2001;(1):43-49. (In Russ.).
  9. Мalygin EN, Malygin SE, Andrianov OV. Simultaneous reconstructive-plastic surgery in patients with breast cancer. In: Theses of the 2nd Congress of Oncologists of the CIS «Oncology 2000» [Tezisy II s”ezda onkologov SNG «Onkologiya 2000»]. Kiev, 23-26 May 2000. Kiev;2000:22. (In Russ.).
  10. Kaviani A, Safavi A, Mirsharifi R. Immediate and delayed contralateral symmetrization in oncoplastic breast reduction: patients’ choices and technique formulation. Plast Reconstr Surg Glob Open. 2015;3(1):286. https://doi.org/10.1097/GOX.0000000000000246
  11. Burlakov AS. Restorative surgery in the treatment of patients with breast cancer. Vestnik Moskovskogo onkologicheskogo obshchestva. 2002;9:1-8. (In Russ.).
  12. Omranipour R, Bobin JY, Esouyeh M. Skin Sparing Mastectomy and Immediate Breast Reconstruction (SSMIR) for early breast cancer: eight years single institution experience. World J Surg Oncol. 2008;6:43. https://doi.org/10.1186/1477-7819-6-43
  13. Pacifico MD, See MS, Cavale N, Collyer J, Francis I, Jones ME, et al. Preoperative planning for DIEP breast reconstruction: early experience of the use of computerised tomography angiography with VoNavix 3D software for perforator navigation. J Plast Reconstr Aesthet Surg. 2009;62(11):1464-1469. https://doi.org/10.1016/j.bjps.2008.04.056
  14. Rietjens M, De Lorenzi F, Venturino M, Petit JY. The suspension technique to avoid the use of tissue expanders in breast reconstruction. Ann Plast Surg. 2005;54(5):467-470.
  15. Spear SL, Bulan EJ. The medial periareolar approach to submuscular augmentation mammaplasty under local anesthesia: a 10-Year follow-up. Plast Reconstr Surg. 2001;108(3):771-775.
  16. Spear SL, Newman MK, Bedford MS, Schwartz KA, Cohen M, Schwartz JS. A retrospective analysis of outcomes using three common methods for immediate breast reconstruction. Plast Reconstr Surg. 2008;122(2):340-347. https://doi.org/10.1097/PRS.0b013e31817d6009
  17. Rezai M, Darsow M, Kummel S, Kramer S. Autologous and alloplastic breast reconstruction-overview of techniques, indications and results. Gynakol Geburtshilfliche Rundsch. 2008;48(2):68-75. https://doi.org/10.1159/000118934
  18. Borovikov AM. Breast reconstruction after mastectomy [Vosstanovlenie grudi posle mastektomii]. Moscow; 2000:5. (In Russ.).
  19. Ravipati NB, Pockaj BA, Harold KL. Laparoscopic mesh repair of transverse rectus abdominus muscle and deep inferior epigastric flap harvest site hernias. Surg Laparosc Endosc Percutan Tech. 2007;17(4):345-348. https://doi.org/10.1097/SLE.0b013e3180640d91
  20. Shons AR, Mosielo G. Postmastectomy brest reconstruction: current techniques. Cancer Сontrol. 2001;8(5):419-426.
  21. Peter G, Cordeiro MD. Breast reconstruction after surgery for breast cancer. N Engl J Med. 2008;359:1590-1601.
  22. Letterman G, Schurter M. Reconstruction of the breast following subcutaneous simple mastectomy. J Am Med Womens Assoc. 1968;23(10):911-915.
  23. Cumberland VH. A preliminars report on the use of prefabricated nylon weave in the repair of ventral hernia. Med J Aust. 1952:1:143.
  24. Scales JT. Discussion on metals and synthetic materials in relation to soft tissues: tissue reaction to synthetic materials. Proc R Soc Med. 1953;46:647.
  25. Razumovskii AYu, Smirnova SV. Use of implantation materials for plastics of the diaphragm in newborns. Khirurgiya. Zhurnal imeni N.I. Pirigova. 2012;11:90-95. (In Russ.).
  26. Spiegel AJ, Butler CE. Recurrence following treatment of ductal carcinoma in situ with skin-sparing mastectomy and immediate breast reconstruction. Plast Reconstr Surg. 2003;111:706-711. https://doi.org/10.1097/01.PRS.0000041440.12442.05
  27. Fedorov IV. Prostheses in hernia surgery: a century-old evolution. Novyi khirurgicheskii arkhiv. 2002;1(4). (In Russ.).
  28. Loustau HD, Mayer HF, Sarrabayrouse M. Immediate prosthetic breast reconstruction: the ensured subpectoral pocket (ESP). J Plast Reconstr Aesthet Surg. 2007;60(11):1233-1238. https://doi.org/10.1097/01.PRS.0000041440.12442.05
  29. Loustau HD, Mayer HF, Sarrabayrouse M. Pocket work for optimising outcomes in prosthetic breast reconstruction. J Plast Reconstr Aesthet Surg. 2009;62(5):626-632. https://doi.org/10.1016/j.bjps.2007.08.037
  30. Wettstein R, Elias B, Bächle A, Vlastos G, Harder Y. Dualmesh-muscle pocket with/without abdominal lift for immediate implant-based breast reconstruction after skin-sparing mastectomy. J Plast Reconstr Aesthet Surg. 2008. Dec 2016. https://doi.org/10.1016/j.bjps.2008.11.043
  31. Surkov NA, Zarinskaya SA, Vissarionov VA. Features of fibroarchitectonics of connective tissue in the implantation zone of the graft implant from the penis. Annaly plasticheskoi i rekonstruktivnoi khirurgii. 2004;(2):54-59. (In Russ.).
  32. Mishalov VG, Khrapach VV, Balaban OV, Unukovich DV, Nazarenko IA, Sivchenko OI, Rybinkina IS, Mishalova AV A method of improving the fixation of soft tissues. Ukraїns’kii zhurnal khіrurgії. 2009;(5):131-132..
  33. Troshenkov EA. Podkozhnaya mastektomiya s odnomomentnoi rekonstruktsiei silikonovym endoprotezom i setchatym implantatom u bol’nykh rakom molochnoi zhelezy. Diss. Moscow; 2011. (In Russ.).
  34. Meyer Ganz O, Tobalem M, Perneger T, Lam T, Modarressi A, Elias B, Pittet B. Risks and benefits of using an absorbable mesh in one-stage immediate breast reconstruction: a comparative study. Plast Reconstr Surg. 2015;135(3):498e-507e. https://doi.org/10.1097/PRS.0000000000001027
  35. Casella D, Bernini M, Bencini L, Roselli J, Lacaria MT, Martellucci J, et al. TiLoop Bra mesh used for immediate breast reconstruction: comparison of retropectoral and subcutaneous implant placement in a prospective single-institution series. Eur J Plast Surg. 2014;37(11):599-604. https://doi.org/10.1007/s00238-014-1001-1
  36. Chun YS, Verma K, Rosen H, et al. Implant-based breast reconstruction using acellular dermal matrix and the risk of postoperative complications. Plast Reconstr Surg. 2010;125(2):429-436. https://doi.org/10.1097/PRS.0b013e3181c82d90
  37. Lanier ST, Wang ED, Chen JJ, et al. The effect of acellular dermal matrix use on complication rates in tissue expander/implant breast reconstruction. Ann Plast Surg. 2010;64(5):674-678. https://doi.org/10.1097/SAP.0b013e3181dba892
  38. Glasberg SB, Light D. AlloDerm and Strattice in breast reconstruction: a comparison and techniques for optimizing outcomes. Plast Reconstr Surg. 2012;129(6):1223-1233. https://doi.org/10.1097/PRS.0b013e31824ec429
  39. Hoppe IC, Yueh JH, Wei CH, Ahuja NK, Patel PP, Datiashvili RO. Complications following expander/implant breast reconstruction utilizing acellular dermal matrix: a systematic review and meta-analysis. Eplasty. 2013;11:417-428.
  40. Salzberg CA. Nonexpansive immediate breast reconstruction using human acellular tissue matrix graft (AlloDerm). Ann Plast Surg. 2006;57(1):1-5. https://doi.org/10.1097/01.sap.0000214873.13102.9f
  41. Seth AK, Hirsch EM, Fine NA, Kim JY. Breast reconstruction — current perspectives and state of the art techniques. Utility of acellular dermis-assisted breast reconstruction in the setting of radiation: a comparative analysis. Plast Reconstr Surg. 2012;130(4):750-758. https://doi.org/10.1097/PRS.0b013e318262f009
  42. Zienowicz RJ, Karacaoglu E. Implant-based breast reconstruction with allograft. Plast Reconstr Surg. 2007;120(2):373-381. https://doi.org/10.1097/01.prs.0000267340.31742.1
  43. Colwell AS, Damjanovic B, Zahedi B, Medford-Davis L, Hertl C, Austen WG, Jr. Retrospective review of 331 consecutive immediate single-stage implant reconstructions with acellular dermal matrix: indications, complications, trends, and costs. Plast Reconstr Surg. 2011;128(6):1170-1178. https://doi.org/10.1097/PRS.0b013e318230c2f6
  44. Nahabedian MY. AlloDerm performance in the setting of prosthetic breast surgery, infection, and irradiation. Plast Reconstr Surg. 2009;124(6):1743-1753. https://doi.org/10.1097/PRS.0b013e3181bf8087
  45. Weichman KE, Wilson SC, Weinstein AL, et al. The use of acellular dermal matrix in immediate two-stage tissue expander breast reconstruction. Plast Reconstr Surg. 2012;129(5):1049-1058. https://doi.org/10.1097/PRS.0b013e31824a2acb
  46. Weichman K, Disa J. Prosthetic breast reconstruction with acellular dermal matrix In: Spiegel AJ, ed. Breast reconstruction — current perspectives and state of the art techniques. 2013;ch4:67-80.
  47. Breuing KH, Colwell AS. Inferolateral AlloDerm hammock for implant coverage in breast reconstruction. Ann Plast Surg. 2007;59(3):250-255.
  48. Breuing KH, Warren SM. Immediate bilateral breast reconstruction with implants and inferolateral AlloDerm slings. Ann Plast Surg. 2005;55(3):232-239.
  49. Parks JR, Hammond SE, Walsh WW, Adams RL, Chandler RG, Luce EA. Human acellular dermis versus no acellular dermis in tissue expansion breast reconstruction. Plast Reconstr Surg. 2012;130(4):739-746. https://doi.org/10.1097/PRS.0b013e318262f06e
  50. Vardanian AJ, Clayton JL, Roostaeian J, et al. Comparison of implant-based immediate breast reconstruction with and without acellular dermal matrix. Plast Reconstr Surg. 2011;128(5):403-410. https://doi.org/10.1097/PRS.0b013e31822b6637
  51. Baxter RA. Intracapsular allogenic dermal grafts for breast implant-related problems. Plast Reconstr Surg. 2003;112(6):1692-1696;discussion 1697-1698. https://doi.org/10.1097/01.PRS.0000086365.25453.C3
  52. Becker S, Saint-Cyr M, Wong C, et al. AlloDerm versus DermaMatrix in immediate expander-based breast reconstruction: a preliminary comparison of complication profiles and material compliance. Plast Reconstr Surg. 2009;123(1):1-6;discussion 107-108. https://doi.org/10.1097/PRS.0b013e3181904bff
  53. Bindingnavele V, Gaon M, Ota KS, Kulber DA, Lee DJ. Use of acellular cadaveric dermis and tissue expansion in postmastectomy breast reconstruction. J Plast Reconstr Aesthet Surg. 2007;60(11):1214-1218. https://doi.org/10.1016/j.bjps.2007.03.015
  54. American Society of Plastic Surgeons 2011 Statistics. 2011. Available at: http:// www.plasticsurgery.org/News-and-Resources/2011-Statistics-.html
  55. Spear SL, Parikh PM, Reisin E, Menon NG. Acellular dermis-assisted breast reconstruction. Aesthetic Plast Surg. 2008;32(3): 418-425. https://doi.org/10.1007/s00266-008-9128-8
  56. Liu AS, Kao HK, Reish RG, Hergrueter CA, May JW, Jr., Guo L. Postoperative complications in prosthesis-based breast reconstruction using acellular dermal matrix. Plast Reconstr Surg. 2011;127(5):1755-1762. https://doi.org/10.1097/PRS.0b013e31820cf233
  57. Antony AK, McCarthy CM, Cordeiro PG, et al. Acellular human dermis implantation in 153 immediate two-stage tissue expander breast reconstructions: determining the incidence and significant predictors of complications. Plast Reconstr Surg. 2010;125(6):1606-1614. https://doi.org/10.1097/PRS.0b013e3181d4fb2a
  58. Gamboa-Bobadilla GM. Implant breast reconstruction using acellular dermal matrix. Ann Plast Surg. 2006;56(1):22-25.
  59. Topol BM, Dalton EF, Ponn T, Campbell CJ. Immediate single-stage breast reconstruction using implants and human acellular dermal tissue matrix with adjustment of the lower pole of the breast to reduce unwanted lift. Ann Plast Surg. 2008;61(5):494-499. https://doi.org/10.1097/SAP.0b013e31816d82d9
Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.