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Predictors of psoriatic arthritis
Journal: Russian Journal of Clinical Dermatology and Venereology. 2021;20(5): 7‑15
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To cite this article:
Khismatullina ZR, Koreshkova KM. Predictors of psoriatic arthritis. Russian Journal of Clinical Dermatology and Venereology.
2021;20(5):7‑15. (In Russ.)
https://doi.org/10.17116/klinderma2021200517
Psoriatic arthritis is a chronic inflammatory disease of the joints, spine and enthesis from the group of spondyloarthritis. In 70–84% of cases the psoriasis precedes the psoriatic arthritis by an average of 10 years. Currently, it is considered that psoriatic arthritis is secondary to psoriasis of the skin and develops on average 4 years before skin rashes. However, the skin phenomena manifest earlier than arthritis in 15–20% of cases. Psoriatic arthritis belongs to the group of seronegative peripheral arthritis characterized by parallelism in skin lesions, special radiological manifestations; some of them allow to suspect the psoriatic origin of the disease in the early stages. Along with other seronegative arthritis, the psoriatic arthritis is characterized by multi-factors causes — complex of genetic, immunological, and environmental factors on the pathogenesis. An important feature of this pathology is its manifestation before involvement of all periarticular structures, tendon-ligamentous apparatus that causes difficulties in diagnosis and timely treatment of patients. The article provides a review of the literature on predictors of psoriatic arthritis — factors that allow to anticipate the development and, in some cases, the course of this pathology.
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Received:
19.06.2020
Accepted:
09.07.2021
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