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Varlamov E.E.

FGBU "Moskovskiĭ nauchno-issledovatel'skiĭ institut pediatrii i detskoĭ khirurgii" Minzdrava Rossii

Pampura A.N.

FGBU "Moskovskiĭ nauchno-issledovatel'skiĭ institut pediatrii i detskoĭ khirurgii" Minzdrava Rossii

The interaction of atopic dermatitis with non-allergic diseases (in Russian only)

Authors:

Varlamov E.E., Pampura A.N.

More about the authors

Journal: Russian Journal of Clinical Dermatology and Venereology. 2019;18(3): 345‑353

DOI: 10.17116/klinderma201918031345

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THE INTERACTION OF ATOPIC DERMATITIS WITH NON-ALLERGIC DISEASES (IN RUSSIAN ONLY)
THE INTERACTION OF ATOPIC DERMATITIS WITH NON-ALLERGIC DISEASES (IN RUSSIAN ONLY)

To cite this article:

Varlamov EE, Pampura AN. The interaction of atopic dermatitis with non-allergic diseases (in Russian only). Russian Journal of Clinical Dermatology and Venereology. 2019;18(3):345‑353. (In Russ.)
https://doi.org/10.17116/klinderma201918031345

Подписка 2025-2 (Russian Journal of Clinical Dermatology and Venereology)
 
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Atopic dermatitis (AtD) is a chronic inflammatory disease, the pathogenesis of which is based on the characteristics of the immune response and violation of the barrier properties of the skin. Symptoms of AtD are noted in 20% of children, half of them develop the disease within 1st year of life, and 95% — till 5 years of life. AtD is one of the earliest chronic inflammatory diseases in humans. At the same time, AtD is considered as the first stage of the development of an allergic march — a chronological sequence of the formation of sensitization and clinical manifestations of an allergy (AtD, bronchial asthma, allergic rhinitis). Recently, there is an increasing evidence of the interaction between allergic and non-allergic diseases. The pathogenesis of AtD goes beyond the scope of exclusively allergic pathology, and the concomitant immunological changes can not be interpreted as the exclusive dominance of Th2-immune response, which is peculiar to allergic rhinitis and bronchial asthma. The altered innate and adaptive immune response in patients with AtD induces the formation of inadequate response to various stimuli, which can be realized in the development of certain chronic inflammatory diseases. It is important to consider the possible impact of pharmacotherapy on the likelihood of developing comorbid diseases. In this regard, special attention should be paid to patients with severe AtD, receiving systemic and massive topical pharmacotherapy. This review presents data on the relationship of AtD with various non-allergic diseases: cardiovascular, oncological, metabolic diseases, systemic diseases of connective tissue, hematological, neurological, ophthalmological disorders, diseases of the gastrointestinal tract and non-allergic skin pathology.

Keywords:

atopic dermatitis
allergic march
non-allergic diseases

Authors:

Varlamov E.E.

FGBU "Moskovskiĭ nauchno-issledovatel'skiĭ institut pediatrii i detskoĭ khirurgii" Minzdrava Rossii

Pampura A.N.

FGBU "Moskovskiĭ nauchno-issledovatel'skiĭ institut pediatrii i detskoĭ khirurgii" Minzdrava Rossii

List of references:

  1. Van der Hulst A, Klip H and Brand P. Risk of developing asthma in young children with atopic eczema: A systematic review. J Allergy Clin Immunol. 2007;120(3):565-569. https://doi.org/10.1016/j.jaci.2007.05.042
  2. Katayama I, Aihara M, Ohya Y, Saeki H, Shimojo N, Shoji S, Taniguchi M, Yamada H. Japanese guidelines for atopic dermatitis 2017. Allerg Int. 2017;66(2):230-247. https://doi.org/10.1016/j.alit.2016.12.003
  3. Hjuler K, Böttcher M, Vestergaard C, Deleuran M, Raaby L, Botker H, Iversen L, Kragballe K. Increased prevalence of coronary artery disease in severe psoriasis and severe atopic dermatitis. Am J Med. 2015;128(12):1325-1334.e2. https://doi.org/10.1016/j.amjmed.2015.05.041
  4. Silverberg J, Becker L, Kwasny M, Menter A, Cordoro K, Paller A. Central obesity and high blood pressure in pediatric patients with atopic dermatitis. JAMA Dermatol. 2015;151(2):144. https://doi.org/10.1001/jamadermatol.2014.3059
  5. Drucker A, Li W, Cho E, Li T, Sun Q, Camargo C, Qureshi A. Atopic dermatitis is not independently associated with nonfatal myocardial infarction or stroke among US women. Allergy. 2016;71(10):1496-1500. https://doi.org/10.1111/all.12957
  6. Standl M, Tesch F, Baurecht H, Rodríguez E, Müller-Nurasyid M, Gieger C, Peters A, Wang-Sattler R, Prehn C, Adamski J, Kronenberg F, Schulz H, Koletzko S, Schikowski T, von Berg A, Lehmann I, Berdel D, Heinrich J, Schmitt J, Weidinger S. Association of atopic dermatitis with cardiovascular risk factors and diseases. J Investigat Dermatol. 2017;137(5):1074-1081. https://doi.org/10.1016/j.jid.2016.11.031
  7. Su VY, Chen TJ, Yeh CM, Chou KT, Hung MH, Chu SY, Su KC, Chang YS, Lin YH, Liu CJ. Atopic dermatitis and risk of ischemic stroke: A nationwide population-based study. Ann Med. 2014;46(2):84-89. https://doi.org/10.3109/07853890.2013.870018
  8. Silverberg J. Association between adult atopic dermatitis, cardiovascular disease, and increased heart attacks in three population-based studies. Allergy. 2015;70(10):1300-1308. https://doi.org/10.1111/all.12685
  9. Strom M, Silverberg J. Associations of physical activity and sedentary behavior with atopic disease in United States children. J Pediat. 2016;174:247-253.e3. https://doi.org/10.1016/j.jpeds.2016.03.063
  10. Linos E, Raine T, Alonso A, Michaud D. Atopy and risk of brain tumors: a meta-analysis. J Nation Cancer Institute. 2007;99(20):1544-1550. https://doi.org/10.1093/jnci/djm170
  11. Deckert S, Kopkow C, Schmitt J. Nonallergic comorbidities of atopic eczema: an overview of systematic reviews. Allergy. 2013;69(1):37-45. https://doi.org/10.1111/all.12246
  12. Linabery A, Jurek A, Duval S, Ross J. The association between atopy and childhood/adolescent leukemia: a meta-analysis. Am J Epidemiol. 2010;171(7):749-764. https://doi.org/10.1093/aje/kwq004
  13. Wang H, Rothenbacher D, Löw M, Stegmaier C, Brenner H, Diepgen T. Atopic diseases, immunoglobulin E and risk of cancer of the prostate, breast, lung and colorectum. Int J Cancer. 2006;119(3):695-701. https://doi.org/10.1002/ijc.21883
  14. Jo S, Kim TJ, Lee H, Min YW, Min BH, Lee JH, Son HJ, Rhee PL, Baek SY, Kim SW, Kim JJ. Associations between atopic dermatitis and risk of gastric cancer: a nationwide population-based study. Korean J Gastroenterol. 2018;71(1):38-44. https://doi.org/10.4166/kjg.2018.71.1.38
  15. Arana A, Wentworth C, Fernández-Vidaurre C, Schlienger R, Conde E, Arellano F. Incidence of cancer in the general population and in patients with or without atopic dermatitis in the U.K. Br J Dermatol. 2010;163(5):1036-1043. https://doi.org/10.1111/j.1365-2133.2010.09887.x
  16. Arellano F, Arana A, Wentworth C, Fernández-Vidaurre C, Schlienger R, Conde E. Lymphoma among patients with atopic dermatitis and/or treated with topical immunosuppressants in the United Kingdom. J Allergy Clin Immunol. 2009;123(5):1111-1116.e13. https://doi.org/10.1016/j.jaci.2009.02.028
  17. Chockalingam R, Downing C, Tyring S. Cutaneous Squamous Cell Carcinomas in Organ Transplant Recipients. J Clin Med. 2015;4(6):1229-1239. https://doi.org/10.3390/jcm4061229
  18. Luger T, Boguniewicz M, Carr W, Cork M, Deleuran M, Eichenfield L, Eigenmann P, Fölster-Holst R, Gelmetti C, Gollnick H, Hamelmann E, Hebert AA, Muraro A, Oranje AP, Paller AS, Paul C, Puig L, Ring J, Siegfried E, Spergel JM, Stingl G, Taieb A, Torrelo A, Werfel T, Wahn U. Pimecrolimus in atopic dermatitis: Consensus on safety and the need to allow use in infants. Pediatr Allerg Immunol. 2015;26(4):306-315. https://doi.org/10.1111/pai.12331
  19. Cardwell C, Shields M, Carson D, Patterson C. A meta-analysis of the association between childhood type 1 diabetes and atopic disease. Diabetes Care. 2003;26(9):2568-2574. https://doi.org/10.2337/diacare.26.9.2568
  20. Andersen YMF, Egeberg A, Gislason GH, Skov L, Knop FK, Thyssen JP. Adult atopic dermatitis and the risk of type 2 diabetes. J Allergy Clin Immunol. 2017;139(3):1057-1059. https://doi.org/10.1016/j.jaci.2016.08.049
  21. Zhang A, Silverberg J. Association of atopic dermatitis with being overweight and obese: a systematic review and metaanalysis. J Am Acad Dermatol. 2015;72(4):606-616.e4. https://doi.org/10.1016/j.jaad.2014.12.013
  22. Lim MS, Lee CH, Sim S, Hong SK, Choi HG. Physical activity, sedentary habits, sleep, and obesity are associated with asthma, allergic rhinitis, and atopic dermatitis in korean adolescents. Yonsei Med J. 2017;58(5):1040-1046. https://doi.org/10.3349/ymj.2017.58.5.1040
  23. O’Donovan SM, O’B Hourihane J, Murray DM, Kenny LC, Khashan AS, Chaoimh CN, Irvine AD, Kiely M. Neonatal adiposity increases the risk of atopic dermatitis during the first year of life. J Allergy Clin Immunol. 2016;137(1):108-117. https://doi.org/10.1016/j.jaci.2015.05.035
  24. Silverberg JI, Kleiman E, Lev-Tov H, Silverberg NB, Durkin HG, Joks R, Smith-Norowitz TA. Association between obesity and atopic dermatitis in childhood: A case-control study. J Allergy Clin Immunol. 2011;127(5):1180-1186.e1. https://doi.org/10.1016/j.jaci.2011.01.063
  25. Nino M, Franzese A, Ruggiero Perrino N, Balato N. The Effect of Obesity on Skin Disease and Epidermal Permeability Barrier Status in Children. Pediatr Dermatol. 2012;29(5):567-570. https://doi.org/10.1111/j.1525-1470.2012.01738.x
  26. Gorgievska-Sukarovska B, Lipozencic J, Susac A. Obesity and allergic diseases. Acta Dermatovenerol Croat. 2008;16:231-235.
  27. Hsiao YP, Tsai JD, Muo CH, Tsai CH, Sung FC, Liao YT, Chang YJ, Yang JH. Atopic diseases and systemic lupus erythematosus: an epidemiological study of the risks and correlations. Int J Environ Res Publ Health. 2014;11(8):8112-8122. https://doi.org/10.3390/ijerph110808112
  28. Wu LC, Hwang CY, Chung PI, Hua TC, Chen YD, Chu SY, Lee DD, Chang YT, Wang WJ, Liu HN, Chen CC. Autoimmune disease comorbidities in patients with atopic dermatitis: a nationwide case-control study in Taiwan. Pediatr Allerg Immunol. 2014;25(6):586-92. https://doi.org/10.1111/pai.12274
  29. Rahman A, Isenberg DA. Systemic lupus erythematosus. N. Engl. J. Med. 200828;358(9):929-939. https://doi.org/10.1056/NEJMra071297
  30. Lin C, Lin C, Shen T, Wei C. Epidemiology and risk of juvenile idiopathic arthritis among children with allergic diseases: a nationwide population-based study. Pediatr Rheumatol. 2016;14(1):15. https://doi.org/10.1186/s12969-016-0074-8
  31. Lai N, Tsai T, Koo M, Lu M. Association of rheumatoid arthritis with allergic diseases: a nationwide population-based cohort study. Allergy Asthma Proceedings. 2015;36(5):99-103. https://doi.org/10.2500/aap.2015.36.3871
  32. Wei C, Lin C, Shen T, Li T, Chen A. Atopic dermatitis and association of risk for Henoch–Schönlein purpura (IgA vasculitis) and renal involvement among children. Medicine. 2016;95(3):e2586. https://doi.org/10.1097/md.0000000000002586
  33. Wei CC1, Lin CL, Shen TC, Tsai JD. Atopic dermatitis and association of risk for primary immune thrombocytopenia and autoimmune diseases among children: A nationwide population-based cohort study. Medicine (Baltimore). 2016;95(29):e4226. https://doi.org/10.1097/MD.0000000000004226
  34. Schmitt J, Romanos M, Pfennig A, Leopold K, Meurer M. Psychiatric comorbidity in adult eczema. Br J Dermatol. 2009;161(4):878-883. https://doi.org/10.1111/j.1365-2133.2009.09309.x
  35. Lee SA. Association of atopic dermatitis with depressive symptoms and suicidal behaviors among adolescents in Korea: the 2013 Korean Youth Risk Behavior Survey. BMC Psychiatry. 2017;17(1). https://doi.org/10.1186/s12888-016-1160-7
  36. Yang Y, Tseng K, Chen Y, Yang J. Associations among eczema, asthma, serum immunoglobulin E and depression in adults: a population-based study. Allergy. 2009;65(6):801-802. https://doi.org/10.1111/j.1398-9995.2009.02249.x
  37. Lee SH, Lee SH, Lee SY, Lee B, Lee SH, Park YL. Psychological health status and health-related quality of life in adults with atopic dermatitis: a nationwide cross-sectional study in South Korea. Acta Derm Venereol. 2018;98(1):89-97. https://doi.org/10.2340/00015555-2797
  38. Lee CY, Chen MH, Jeng MJ, Hsu JW, Tsai SJ, Bai YM, Hung GY, Yen HJ, Chen TJ, Su TP. Longitudinal association between early atopic dermatitis and subsequent attention-deficit or autistic disorder. Medicine. 2016;95(39): e5005. https://doi.org/10.1097/md.0000000000005005
  39. Strom M, Fishbein A, Paller A, Silverberg J. Association between atopic dermatitis and attention deficit hyperactivity disorder in U.S. children and adults. Br J Dermatol. 2016;175(5):920-929. https://doi.org/10.1111/bjd.14697
  40. Schmitt J, Buske-Kirschbaum A, Roessner V. Is atopic disease a risk factor for attention-deficit/hyperactivity disorder? A systematic review. Allergy. 2010;65(12):1506-1524. https://doi.org/10.1111/j.1398-9995.2010.02449.x
  41. Romanos M, Gerlach M, Warnke A, Schmitt J. Association of attention-deficit/hyperactivity disorder and atopic eczema modified by sleep disturbance in a large population-based sample. J Epidemiol Community Health. 2009;64(3):269-273. https://doi.org/10.1136/jech.2009.093534
  42. Carroll C, Balkrishnan R, Feldman S, Fleischer A, Manuel J. The burden of atopic dermatitis: impact on the patient, family, and society. Pediatr Dermatol. 2005;22(3):192-199. https://doi.org/10.1111/j.1525-1470.2005.22303.x
  43. Oades R, Dauvermann M, Schimmelmann B, Schwarz M, Myint A. Attention-deficit hyperactivity disorder (ADHD) and glial integrity: S100B, cytokines and kynurenine metabolism - effects of medication. Behavioral Brain Functions. 2010;6(1):29. https://doi.org/10.1186/1744-9081-6-29
  44. Silverberg J, Joks R, Durkin H. Allergic disease is associated with epilepsy in childhood: a US population-based study. Allergy. 2013;69(1):95-103. https://doi.org/10.1111/all.12319
  45. Yaghmaie P, Koudelka C, Simpson E. Mental health comorbidity in patients with atopic dermatitis. J Allergy Clin Immunol. 2013;131(2):428-433. https://doi.org/10.1016/j.jaci.2012.10.041
  46. Adil H, Siegfried E, Armbrecht E. The impact of severe atopic dermatitis: analysis of comorbidities. J Am Acad Dermatol. 2014;70(5):AB66. https://doi.org/10.1016/j.jaad.2014.01.271
  47. Croonenberghs J, Bosmans E, Deboutte D, Kenis G, Maes M. Activation of the inflammatory response system in autism. Neuropsychobiology. 2002;45(1):1-6. https://doi.org/10.1159/000048665
  48. Yarlagadda A, Alfson E, Clayton AH. The blood brain barrier and the role of cytokines in neuropsychiatry. Psychiatry (Edgmont). 2009;6:18–22.
  49. Muñoz-Jareño N1, Fernández-Mayoralas DM, Martínez-Cervell C, Campos-Castelló J. Relationship between migraine and atopy in childhood: a retrospective case-control study. Rev Neurol. 2011;53(12):713-20.
  50. Shreberk-Hassidim R, Hassidim A, Gronovich Y, Dalal A, Molho-Pessach V, Zlotogorski A. Atopic dermatitis in israeli adolescents from 1998 to 2013: trends in time and association with migraine. Pediatr Dermatol. 2017;34(3):247-252. https://doi.org/10.1111/pde.13084
  51. Katayama I, Kohno Y, Akiyama K, Aihara M, Kondo N, Saeki H, Shoji S, Yamada H, Nakamura K. Japanese guideline for atopic dermatitis 2014. Allergol Int. 2014;63(3):377-398. https://doi.org/10.2332/allergolint.14-rai-0769
  52. Carmi E, Defossez-Tribout C, Ganry O, Cene S, Tramier B, Milazzo S, Lok C. Ocular complications of atopic dermatitis in children. Acta Dermato-Venereologica. 2006;86(6):515-517. https://doi.org/10.2340/00015555-0163
  53. Nagaki Y, Hayasaka S, Kadoi C. Cataract progression in patients with atopic dermatitis. J Cataract Refr Surg. 1999;25(1):96-99. https://doi.org/10.1016/s0886-3350(99)80018-2
  54. Rim TH, Kim DW, Kim SE, Kim SS. Factors associated with cataract in Korea: a community health survey 2008-2012. Yonsei Med J. 2015;56(6):1663-1670. https://doi.org/10.3349/ymj.2015.56.6.1663
  55. Handa S, Jain A, Kanwar A, Kaujalgi R. Ocular abnormalities in atopic dermatitis in Indian patients. Ind J Dermatol, Venereol and Leprol. 2009; 75(2):148. https://doi.org/10.4103/0378-6323.48659
  56. Haeck I, Rouwen T, Timmer-de Mik L, de Bruin-Weller M, Bruijnzeel-Koomen C. Topical corticosteroids in atopic dermatitis and the risk of glaucoma and cataracts. J Am Acad Dermatol. 2011;64(2):275-281. https://doi.org/10.1016/j.jaad.2010.01.035
  57. Yoo T, Kim S, Seo K. Age-related cataract is associated with elevated serum immunoglobulin E levels in the South Korean population: a cross-sectional study. PLOS ONE. 2016;11(11):e0166331. https://doi.org/10.1371/journal.pone.0166331
  58. Perugia C, Saraceno R, Ventura A, Lorè B, Chiaramonte C, Docimo R, Chimenti S. Atopic dermatitis and dental manifestations. G Ital Dermatol Venereol. 2017;152(2):122-125. https://doi.org/10.23736/S0392-0488.16.05224-X
  59. Kalhan TA, Loo EX, Kalhan AC, Kramer MS, H, Shek LP, Goh A, Chong YS, Lee BW, Gluckman P, Kwek K, Saw SM, Godfrey K, Hsu CY. Atopic dermatitis and early childhood caries: Results of the GUSTO study. J Allergy Clin Immunol. 2017;139(6):2000-2003. https://doi.org/10.1016/j.jaci.2016.10.038
  60. Kulakova EV, Elizarova VM, Pampura AN, Vinogradova TV, Varlamov EE. The role of endogenous antimicrobial peptides (catelicidin LL-37) in the development of caries at children with atopic dermatitis. Lech prof. 2013;1(5):73-76 (In Russ.)
  61. Ress K, Annus T, Putnik U, Luts K, Uibo R, Uibo O. Celiac disease in children with atopic dermatitis. Pediatr Dermatol. 2014;31(4):483-488. https://doi.org/10.1111/pde.12372
  62. Egeberg A, Andersen Y, Gislason G, Skov L, Thyssen J. Gallstone risk in adult patients with atopic dermatitis and psoriasis: possible effect of overweight and obesity. Acta Dermato Venereologica. 2017;97(5):627-631. https://doi.org/10.2340/00015555-2622
  63. Drucker AM, Thompson JM, Li WQ, Cho E, Li T, Guttman-Yassky E, Qureshi AA. Incident alopecia areata and vitiligo in adult women with atopic dermatitis: Nurses’ Health Study 2. Allergy. 2017;72(5):831-834. https://doi.org/10.1111/all.13128
  64. Magen E, Chikovani T, Waitman DA, Kahan NR. Association of alopecia areata with atopic dermatitis and chronic spontaneous urticaria. Allergy Asthma Proc. 2018;39(2):96-102. https://doi.org/10.2500/aap.2018.39.4114
  65. Ezzedine K, Diallo A, Léauté-Labrèze C, Seneschal J, Boniface K, Cario-André M, Prey S, Ballanger F, Boralevi F, Jouary T, Mossalayi D, Taieb A. Pre- vs. post-pubertal onset of vitiligo: multivariate analysis indicates atopic diathesis association in pre-pubertal onset vitiligo. Br J Dermatol. 2012;167(3):490-495. https://doi.org/10.1111/j.1365-2133.2012.11002.x
  66. Alexopoulos A, Kakourou T, Orfanou I, Xaidara A, Chrousos G. Retrospective analysis of the relationship between infantile seborrheic dermatitis and atopic dermatitis. Pediatr Dermatol. 2013;31(2):125-130. https://doi.org/10.1111/pde.12216
  67. Chia B, Tan A, Tey H. Primary localized cutaneous amyloidosis: association with atopic dermatitis. J Eur Acad Dermatol Venereol. 2013;28(6):810-813. https://doi.org/10.1111/jdv.12144
  68. Thyssen J, McFadden J, Kimber I. The multiple factors affecting the association between atopic dermatitis and contact sensitization. Allergy. 2013;69(1):28-36. https://doi.org/10.1111/all.12358
  69. Thyssen J, Johansen J, Linneberg A, Menné T. The epidemiology of hand eczema in the general population — prevalence and main findings. Contact Dermatitis. 2010;62(2):75-87. https://doi.org/10.1111/j.1600-0536.2009.01669.x
  70. Mailhol C, Lauwers-Cances V, Rancé F, Paul C, Giordano-Labadie F. Prevalence and risk factors for allergic contact dermatitis to topical treatment in atopic dermatitis: a study in 641 children. Allergy. 2009;64(5):801-806. https://doi.org/10.1111/j.1398-9995.2008.01890.x
  71. Simpson E. Comorbidity in Atopic Dermatitis. Cur Dermatol Rep. 2012;1(1):29-38. https://doi.org/10.1007/s13671-011-0003-5

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The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.
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