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Matushevskaia E.V.

FGOU Institut povysheniia kvalifikatsii Federal'nogo mediko-biologicheskogo agentstva RF, Moskva

Svirshchevskaia E.V.

Institut bioorganicheskoĭ khimii im. M.M. Shemiakina i Iu.A. Ovchinnikova RAN, Moskva, 117997, Rossiĭskaia Federatsiia

Matushevskaia Iu.I.

OOO "Kliniki Chaĭka", 123317, Moskva, Rossiĭskaia Federatsiia

Kotsareva O.D.

FGBUN «Institut bioorganicheskoj himii im. akademikov M.M. Shemjakina i Ju.A. Ovchinnikova» RAN, Moskva, Rossija, 117997

Topical local anesthetics in cosmetology

Authors:

Matushevskaia E.V., Svirshchevskaia E.V., Matushevskaia Iu.I., Kotsareva O.D.

More about the authors

Journal: Russian Journal of Clinical Dermatology and Venereology. 2017;16(3): 89‑96

DOI: 10.17116/klinderma201716389-96

Views: 18995

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To cite this article:

Matushevskaia EV, Svirshchevskaia EV, Matushevskaia IuI, Kotsareva OD. Topical local anesthetics in cosmetology. Russian Journal of Clinical Dermatology and Venereology. 2017;16(3):89‑96. (In Russ.)
https://doi.org/10.17116/klinderma201716389-96

 
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Patient-centered medical technology is a priority area of public health. Many therapeutic and cosmetic manipulations cause iatrogenic pain, whose elimination requires the development of new approaches to anesthesia. This review focus on the analysis of the mechanism of action, efficacy and safety of anesthetic drugs for local topical use in cosmetology. We report the data of comparative studies on the effectiveness of topical local anesthetics (TLA) in various cosmetic manipulations. The advantages of a cream, including lidocaine/prilocaine combination, versus other TLAs was shown. Reliable efficacy, safety, and high patient’s and doctor’s adherence to the treatment suggests that 2.5% lidocaine + 2.5% prilocaine cream is a first-line drug and optimal TLA for various invasive procedures.

Keywords:

anesthesia
topical local anesthetics
invasive cosmetic manipulations
combination of 25% lidocaine and 25% prilocaine
efficacy
safety
Akriol Pro

Authors:

Matushevskaia E.V.

FGOU Institut povysheniia kvalifikatsii Federal'nogo mediko-biologicheskogo agentstva RF, Moskva

Svirshchevskaia E.V.

Institut bioorganicheskoĭ khimii im. M.M. Shemiakina i Iu.A. Ovchinnikova RAN, Moskva, 117997, Rossiĭskaia Federatsiia

Matushevskaia Iu.I.

OOO "Kliniki Chaĭka", 123317, Moskva, Rossiĭskaia Federatsiia

Kotsareva O.D.

FGBUN «Institut bioorganicheskoj himii im. akademikov M.M. Shemjakina i Ju.A. Ovchinnikova» RAN, Moskva, Rossija, 117997

List of references:

  1. Khavinson VKh, Benberin VV, Mikhailova ON, Sidorenko AV. Starenie v stranakh s razvi-vayushcheisya ekonomikoi: vyzovy i vozmozhnosti. Upravlencheskoe kon-sul’tirovanie. 2015;11:50-58. (In Russ.).
  2. American Society of Plastic Surgeons ASPS.2012
  3. Otechestvennaya klassifikatsiya sposobov mestnoi anestezii po A. A. Vishnevskomu; 1974; A. F. Bizyaevu, 1998.
  4. Calvey TN, Williams NE. Principles and Practice of Pharmacology for Anaesthetists. Blackwell Publishing; 2001.
  5. Cassuto J, Sinclair R, Bonderovic M. Anti-inflammatory properties of local anesthetics and their present and potential clinical implications. Acta Anasthesiol Scand. 2006;50:265-282. https:/doi.org/10.1111/j.1399-6576.2006.00936.x
  6. Оhlsen L, et al. Topical anaesthesia of the skin. Paediatric Anaesthesia. 1993;3:129-138.
  7. Stolyarenko PYu. Istoriya obezbolivaniya v stomatologii. Samara; 2001. (In Russ.).
  8. Zhigul’tsova TI, Parkaeva LV, Il’ina EE, Vissarionov VA. Opyt primeneniya 5% krema Emla v praktike dermatokosmetologa. Russkii meditsinskii zhurnal. 2008;16:8:570-571. (In Russ.).
  9. Ranneva E.A. Primenenie krema Emla v kompleksnoi korrektsii kosmeticheskikh nedostatkov. Eksperimental’naya klinicheskaya dermatokosmetologiya. 2010;2:48-53. (In Russ.).
  10. Aslaksen PM, Zwarg ML, Eilertsen HI, Gorecka MM, Bjørkedal E. Opposite effects of the same drug: reversal of topical analgesia by nocebo information. Pain. 2015 Jan;156(1):39-46. https:/doi.org/10.1016/j.pain.0000000000000004
  11. Lee SH, Pakdeethai J, Toh MP, Aw DC. A Double-Blind, Randomised, Placebo-Controlled Trial of EMLA Cream (Eutectic Lidocaine/Prilocaine Cream) for Analgesia Prior to Cryotherapy of Plantar Warts in Adults. Ann Acad Med Singapore. 2014 Oct;43(10):511-514.
  12. Koppel RA, Coleman KM, Coleman WP. The efficacy of EMLA versus ELA-Max for pain relief in medium-depth chemical peeling: a clinical and histopathologic evaluation. Dermatol Surg. 2000 Jan;26(1):61-64.
  13. Greveling K, Prens EP, Ten Bosch N, van Doorn MB. Comparison of lidocaine/tetracaine cream and lidocaine/prilocaine cream for local anaesthesia during laser treatment of acne keloidalis nuchae and tattoo removal: results of two randomized controlled trials. Br J Dermatol. 2016 Jul 5. https:/doi.org/10.1111/bjd.14848. Epub 2016 Dec10
  14. Hernandez E, Gonzalez S. Evaluation of Topical Anesthetics by Laser-Induced Sensation. Lasers in Surgery and Medicine. 23:167-171.

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