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Baĭtiakov V.V.

FGBOU VPO "Mordovskiĭ gosudarstvennyĭ universitet im. N.P. Ogareva"

Filimonkova N.N.

Ural Research Institute of Dermatovenerology and Immunopathology, Ekaterinburg

Clinical and immunological evaluation of the efficiency of extracorporeal blood correction in disseminated psoriasis

Authors:

Baĭtiakov V.V., Filimonkova N.N.

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Journal: Russian Journal of Clinical Dermatology and Venereology. 2012;10(4): 10‑15

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CLINICAL AND IMMUNOLOGICAL EVALUATION OF THE EFFICIENCY OF EXTRACORPOREAL BLOOD CORRECTION IN DISSEMINATED PSORIASIS
CLINICAL AND IMMUNOLOGICAL EVALUATION OF THE EFFICIENCY OF EXTRACORPOREAL BLOOD CORRECTION IN DISSEMINATED PSORIASIS

To cite this article:

Baĭtiakov VV, Filimonkova NN. Clinical and immunological evaluation of the efficiency of extracorporeal blood correction in disseminated psoriasis. Russian Journal of Clinical Dermatology and Venereology. 2012;10(4):10‑15. (In Russ.)

Подписка 2026 Клиническая дерматология и венерология (Russian Journal of Clinical Dermatology and Venereology)
 
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

The effect of plasmapheresis and its modification with ozonation of returned red blood cell suspension on the course of the cutaneous process and on some immunological parameters was investigated in patients with disseminated psoriasis. Its clinical picture, the parameters of humoral immunity and a phagocytic process, and the serum levels of cytokines were studied over time. Patients with an exacerbation of disseminated psoriasis were observed to have elevated levels of tumor necrosis factor-α, interlekin-2, circulating immune complexes, immunoglobulins M and A, and enhanced neutrophil defense activity. There was a relationship between the study parameters to the clinical features of the disease, gender, age, and a family history.

Keywords:

psoriasis
cytokines
phagocytic process
immunoglobulins
immune complexes
plasmapheresis

Authors:

Baĭtiakov V.V.

FGBOU VPO "Mordovskiĭ gosudarstvennyĭ universitet im. N.P. Ogareva"

Filimonkova N.N.

Ural Research Institute of Dermatovenerology and Immunopathology, Ekaterinburg

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References:

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  3. Katunina O.R. Rol' vrozhdennogo i adaptivnogo immuniteta v patogeneze psoriaza. Vestn dermatol i venerol 2009; 5: 43-48.
  4. Lepakhin V.K., Astakhova A.V., Ovchinnikova E.A., Ovchinnikova L.K. Vrachebnye oshibki kak prichina oslozhnenii lekarstvennoi terapii. Kachestv klin prakt 2002; 1: 71-77.
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  7. Potekaev N.S., Kudrina M.I., Gorshkova N.N. i dr. Plazmaferez v terapii refrakternykh form psoriaza. Vestn dermatol i venerol 1990; 10: 35-37.
  8. Piksin I.N., Fedoseikin I.V., Byakin S.P. Kvantovye i efferentnye metody lecheniya v khirurgii. M: Nauka 2010; 248.
  9. Veksler N.Yu., Boyarinov G.A., Makarov N.A. i dr. Taktika intensivnoi terapii bol'nykh s ostrym destruktivnym pankreatitom. Vestn int terap 2004; 5: 180-183.
  10. Danilov A.Yu. Kliniko-patogeneticheskoe obosnovanie primeneniya efferentnykh metodov i ozonoterapii v rannei reabilitatsii bol'nykh, perenesshikh miomektomiyu: Avtoref. dis. … d-ra med. nauk. M 2009; 48.
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  12. Bel'tyukova A.S., Sysoev K.A., Khobeish M.M. i dr. Opredelenie urovnya 50 tsitokinov v syvorotke krovi bol'nykh psoriazom. Sovrem probl dermatoven immunol i vrachebn kosmetol 2011; 2: 15: 9-14.
  13. Kashperova O.G. Klinicheskaya effektivnost' i perenosimost' timodepressina v terapii detei s psoriazom. Klin dermatol i venerol 2009; 3: 41-45.
  14. Bocci V. Ozone as a bioregulator. Pharmacology and toxicology of ozonetherapy today. J Biolog Regul Homeostat Agents 1997; 10: 2-3: 31-53.
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