The history and modern approaches to clinical use of antihistaminic drugs

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Antihistamines are the cornerstone of treatment of a wide spectrum of allergic diseases in our days. The authors consider mechanisms of their action, clinical efficacy, and safety of two generations of antihistamines in the context of fundamental principles of evidence-based medicine and modern international guidelines and position papers.

Keywords:

antihistaminic drugs

efficacy

safety

evidence-based medicine

position paper

Authors:

Emel’yanov A.V.

Department of Cardiovascular Surgery, Russian Cardiology Research and Production Complex, Moscow, Russia

Kochergin N.G.

I.M. Sechenov Moscow Medical Academy

Goriachkina L.A.

Russian Medical Academy of Postgraduate Education

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