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Ryabov A.B.

Hertsen Moscow Oncology Research Institute

Pikin O.V.

Hertsen Moscow Oncology Research Institute

Glushko V.A.

Herzen Research Institute of Oncology

Kolbanov K.I.

P.A. Herzen Moscow Oncology Research Institute - Branch National Medical Radiology Research Center of the Ministry of Health of the Russia

Bagrov V.A.

Herzen Research Institute of Oncology

Aleksandrov O.A.

Herzen Moscow Oncology Research Institute — Branch Campus of the National Medical Radiology Research Center

Barmin V.V.

Herzen Research Institute of Oncology

Martynova D.E.

Herzen Research Institute of Oncology

Vorobyeva E.Yu.

Hertzen Moscow Cancer Research Center

Larionov D.A.

Hertzen Moscow Cancer Research Center

Surgical treatment of lung cancer in patients over 75 years old

Authors:

Ryabov A.B., Pikin O.V., Glushko V.A., Kolbanov K.I., Bagrov V.A., Aleksandrov O.A., Barmin V.V., Martynova D.E., Vorobyeva E.Yu., Larionov D.A.

More about the authors

Journal: Pirogov Russian Journal of Surgery. 2022;(12): 20‑30

DOI: 10.17116/hirurgia202212120

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Table of contents

SURGICAL TREATMENT OF LUNG CANCER IN PATIENTS OVER 75 YEARS OLD
SURGICAL TREATMENT OF LUNG CANCER IN PATIENTS OVER 75 YEARS OLD

To cite this article:

Ryabov AB, Pikin OV, Glushko VA, et al. . Surgical treatment of lung cancer in patients over 75 years old. Pirogov Russian Journal of Surgery. 2022;(12):20‑30. (In Russ.)
https://doi.org/10.17116/hirurgia202212120

Подписка 2025-2 (Pirogov Russian Journal of Surgery)
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OBJECTIVE

To analyze surgical treatment of lung cancer in patients over 75 years old.

MATERIAL AND METHODS

The study enrolled 73 patients. Lobectomy was performed in 50 (68.5%) patients, segmentectomy — 14 (19.2%), pneumonectomy — 4 (5.5%), bilobectomy — 3 (4.1%), wedge resection — 2 (2.7%) patients. The most common clinical scenario was lobectomy for lung adenocarcinoma stage I. Metastases in lymph nodes were noted in 32.9% of cases. Among 9 patients with pN2 (12.9%), lesion of mediastinal lymph nodes was preoperatively diagnosed in 4 (44%) cases. Mean tumor size was 3 (1—14) cm.

RESULTS

Overall morbidity was 16.4%, mortality 5.5%. Multivariate analysis revealed the most significant risk factors such as stage IIIb (OR 9.3, 95% CI 1.365—63.816, p=0.023), pN1 (OR 3.889, 95% CI 1.008—14.999, p=0.049), pN2 (OR 5.300, 95% CI 1.170—23.999, p=0.030), central cancer (OR 7.572, 95% CI 1.742—32.884, p=0.007).

CONCLUSION

Surgical treatment of lung cancer patients over 75 years old may be completed safely and effectively in careful preoperative selection of patients. The most important risk factors of postoperative complications are cancer stage IIIb stage, lymph node lesion and central cancer.

Keywords:

lung cancer
surgery
elderly patients

Authors:

Ryabov A.B.

Hertsen Moscow Oncology Research Institute

Pikin O.V.

Hertsen Moscow Oncology Research Institute

Glushko V.A.

Herzen Research Institute of Oncology

Kolbanov K.I.

P.A. Herzen Moscow Oncology Research Institute - Branch National Medical Radiology Research Center of the Ministry of Health of the Russia

Bagrov V.A.

Herzen Research Institute of Oncology

Aleksandrov O.A.

Herzen Moscow Oncology Research Institute — Branch Campus of the National Medical Radiology Research Center

Barmin V.V.

Herzen Research Institute of Oncology

Martynova D.E.

Herzen Research Institute of Oncology

Vorobyeva E.Yu.

Hertzen Moscow Cancer Research Center

Larionov D.A.

Hertzen Moscow Cancer Research Center

Received:

04.05.2022

Accepted:

14.06.2022

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