Comparative long-term results of surgical treatment of patients with diffuse toxic goiter

Aristarkhov V.G.

Department of Surgical Diseases with Course of Urology, Acad. I.P. Pavlov Ryazan State Medical University, Ministry of Health of Russia, Ryazan, Russia;
City Clinical Hospital One, Ryazan, Russia

Kvasov A.V.

Pavlov Ryazan State Medical University, Ryazan, Russia

Donyukov A.I.

Pavlov Ryazan State Medical University, Ryazan, Russia

Aristarkhov R.V.

Pavlov Ryazan State Medical University, Ryazan, Russia

Biryukov S.V.

Pavlov Ryazan State Medical University, Ryazan, Russia

Pusin D.A.

Pavlov Ryazan State Medical University, Ryazan, Russia

Comparative long-term results of surgical treatment of patients with diffuse toxic goiter

Authors:

Aristarkhov V.G., Kvasov A.V., Donyukov A.I., Aristarkhov R.V., Biryukov S.V., Pusin D.A.

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Journal: Pirogov Russian Journal of Surgery. 2017;(8): 13‑17

DOI: 10.17116/hirurgia2017813-17

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To cite this article:

Aristarkhov VG, Kvasov AV, Donyukov AI, Aristarkhov RV, Biryukov SV, Pusin DA. Comparative long-term results of surgical treatment of patients with diffuse toxic goiter. Pirogov Russian Journal of Surgery. 2017;(8):13‑17. (In Russ.)
https://doi.org/10.17116/hirurgia2017813-17

Подписка 2025 (Pirogov Russian Journal of Surgery)

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Aim. To analyze long-term outcomes of Graves’ disease management. Material and methods. There were 428 patients for the periods 2000—2004 and 2005—2010. Patients were called for examination and thyroid status control. 2 groups were compared: group 1 of 203 patients and group 2 of 225 patients. Results. It was found that after subtotal resection by original technique (patent 1802309 of the Russian Federation, MPK 5 G01N1, 1/28) in group 1 euthyroid state was observed in more than half (59.4%) of patients, hypothyroidism — 30.3% and recurrence — in 10.3% 10 years postoperatively. At the same time most of patients of group 2 (71.6%) after predominant thyroidectomy had hypothyroidism, euthyroid state was only in 24%. Postoperative recurrent diffuse toxic goiter incidence was 4.7%. Conclusion. The dynamics of postoperative thyroid status depending on type of surgery and follow-up was presented.

Keywords:

diffuse toxic goiter

surgical treatment

long-term results

thyroidectomy

subtotal resection of the thyroid gland

Authors:

Aristarkhov V.G.

Department of Surgical Diseases with Course of Urology, Acad. I.P. Pavlov Ryazan State Medical University, Ministry of Health of Russia, Ryazan, Russia;
City Clinical Hospital One, Ryazan, Russia

Kvasov A.V.

Pavlov Ryazan State Medical University, Ryazan, Russia

Donyukov A.I.

Pavlov Ryazan State Medical University, Ryazan, Russia

Aristarkhov R.V.

Pavlov Ryazan State Medical University, Ryazan, Russia

Biryukov S.V.

Pavlov Ryazan State Medical University, Ryazan, Russia

Pusin D.A.

Pavlov Ryazan State Medical University, Ryazan, Russia

List of references:

Aristarhov VG, Kvasov AV. To the question about the causes and treatments of patients with relapse of Graves’ disease. Rossijskij mediko-biologicheskij vestnik im. akad. I.P. Pavlova. 2015;2:106-110. (In Russ.). https://doi.org/10.17816/pavlovj20152106-110
Latkina NV. Prognostic value clinical and immunological indicators in determining the outcomes of surgical treatment of diffuse toxic goiter [dissertation]. M. 2000. (In Russ.).
Kuvtev N, Petkov R, Iaruvmov N. Subtotal resection of thyroid gland — optimal method for treatment of Bazedow disease. Khirurgiia (Sofia). 2007;3:9-13.
Romanchishen AF i dr. Results of surgical treatment of diffuse toxic goiter in adults, children and male patients. Articles of XI (XIII) Russian Symposium with international participation in surgical endocrinology «Modern aspects of surgical endocrinology»; July 15—18, 2003, St. Petersburg. SPb. 2003;216-226. (In Russ.).
Abdurahmanov ShM. The dynamics of immunological parameters of patients with thyrotoxicosis during extended resection of the thyroid gland with reimplantation [dissertation]. Tashkent. 2007. (In Russ.).
Adrianovskaja NV. Long-term results of surgical treatment of patients with diffuse toxic goiter in endemic areas[dissertation. Permian. 2007. (In Russ.).]
Bovykina GA, Men’kov AV. The value of the results of intraoperative cytomorphometry when choosing the scope of operation in patients with diffuse toxic goiter. Materials of XVI Russian symposium with international participation on surgical endocrinology «Modern aspects of surgical endocrinology»; September 18—20, 2007, Saransk. Saransk. 2007;32. (In Russ.).
Vetshev PS, Mamaeva SK. Predictors of surgical treatment of diffuse toxic goiter. Hirurgija. 2006;2:63-68. (In Russ.).
Valdina EA. Thyroid disease. SPb.: Peter; 2001. (In Russ.).
Dedov II, Troshina EA, Antonova SS, Aleksandrova GF, Zilov AV. Autoimmune thyroid disease: state of problem. Problemyj endokrinologii. 2002;48(2):6-13. (In Russ.).
Makarov IV, Galkin RA, Shibanov VYa, Andreev MM, Sidorov AYu. Evaluation of long-term outcomes and quality of life of patients after surgical treatment of diffuse toxic goiter. Collection of scientific abstracts and articles of «Health and Education in the XXI century», 2010, Samara. Samara. 2010;12(4):473-474. (In Russ.).
Petunina NA. Prognostic factors and optimization methods for treating of Graves’ disease [dissertation]. M. 2004. (In Russ.).
Fadeev VV. Diagnosis and treatment of toxic goiter. Russkij medicinskij zhurnal. 2002;10(11):513-516. (In Russ.).
Aristarhov VG. Surgical treatment of diffuse toxic goiter in the light of prevention of postoperative hypothyroidism. Articles of XI (XIII) Russian Symposium with international participation in surgical endocrinology «Modern aspects of surgical endocrinology», July 15—18, 2003, St. Petersburg. SPb. 2003;16-23. (In Russ.).
Aristarhov VG. Tactics of the surgeon for the prevention of postoperative hypothyroidism in patients with autoimmune thyroid disease [dissertation]. Ryazan. 1996. (In Russ.).
Danilov NV, Kuznecova OS. Violation of hormonal regulation of bone mineral density after surgical treatment of thyroid diseases. Nauka molodyh — Eruditio Juvenium. 2013;4:73-80. (In Russ.).
Sahipov DR. The differentiated tactics of the surgical treatment of patients with diffuse toxic goiter [dissertation]. Samara. 2016. (In Russ.).

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