Features of cytokines profile in various forms of systemic inflammatory response syndrome in patients with acute calculous cholecystitis

Gadzhiev J.N.; Gadzhiev N.J.; Mamedova Z.B.

doi:https://doi.org/10.17116/hirurgia20171061-64

Gadzhiev J.N.

Azerbaijan Medical University, Baku, Azerbaijan

Gadzhiev N.J.

Azerbaijan Medical University, Baku, Azerbaijan

Mamedova Z.B.

Nakhichevan Diagnostic Medical Center, Nakhichevan, Azerbaijan

Features of cytokines profile in various forms of systemic inflammatory response syndrome in patients with acute calculous cholecystitis

Authors:

Gadzhiev J.N., Gadzhiev N.J., Mamedova Z.B.

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Journal: Pirogov Russian Journal of Surgery. 2017;(10): 61‑64

DOI: 10.17116/hirurgia20171061-64

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Gadzhiev JN, Gadzhiev NJ, Mamedova ZB. Features of cytokines profile in various forms of systemic inflammatory response syndrome in patients with acute calculous cholecystitis. Pirogov Russian Journal of Surgery. 2017;(10):61‑64. (In Russ.)
https://doi.org/10.17116/hirurgia20171061-64

Подписка 2026 Хирургия. Журнал им. Н.И. Пирогова (Pirogov Russian Journal of Surgery)

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Abstract:

Aim. Comparative evaluation of systemic concentration of some cytokines in various forms of SIR in patients with acute calculous cholecystitis. Material and methods. The study included 32 patients with acute calculous cholecystitis and SIR. According to ASSR/SCCM criteria SIR 2 was in 11, SIR 3 — in 8, SIR 4 — in 7 patients, 6 patients had sepsis. Serum TNF-α, IL-6, IL-4 and IL-10 were determined prior to surgery, in 3 and 7 days postoperatively by using of ELISA. Results. There was a cytokine imbalance whose severity depended on SIR severity and presence of sepsis. Conclusion. Surgical intervention on background of basis therapy does not correct cytokine imbalance. So adequate pharmacological correction is required.

Keywords:

acute calculous cholecystitis

sepsis

systemic inflammatory response

Authors:

Gadzhiev J.N.

Azerbaijan Medical University, Baku, Azerbaijan

Gadzhiev N.J.

Azerbaijan Medical University, Baku, Azerbaijan

Mamedova Z.B.

Nakhichevan Diagnostic Medical Center, Nakhichevan, Azerbaijan

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References:

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