The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-0604
+8 800 250-18-12
  • (toll-free number for subscriptions)
    Mon-Fri from 10 a.m. to 6 p.m.

  • © 1998-2025
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Klimov A.E.

Vinogradov University Clinical Hospital — Patrice Lumumba Peoples’ Friendship University of Russia

Leonovich A.M.

Vinogradov University Clinical Hospital — Patrice Lumumba Peoples’ Friendship University of Russia

Kosachenko M.V.

Vinogradov University Clinical Hospital — Patrice Lumumba Peoples’ Friendship University of Russia

Barkhudarov A.A.

Vinogradov University Clinical Hospital — Patrice Lumumba Peoples’ Friendship University of Russia

Gogichashvili V.V.

Vinogradov University Clinical Hospital — Patrice Lumumba Peoples’ Friendship University of Russia

Comparative analysis of laparoscopic cholecystectomy outcomes in acute calculous cholecystitis: importance of indocyanine green, optimal dosing regimen

Authors:

Klimov A.E., Leonovich A.M., Kosachenko M.V., Barkhudarov A.A., Gogichashvili V.V.

More about the authors

Journal: Pirogov Russian Journal of Surgery. 2024;(11): 72‑76

DOI: 10.17116/hirurgia202411172

Read: 1094 times

Buy for 300₽
Contact the author
Table of contents

COMPARATIVE ANALYSIS OF LAPAROSCOPIC CHOLECYSTECTOMY OUTCOMES IN ACUTE CALCULOUS CHOLECYSTITIS: IMPORTANCE OF INDOCYANINE GREEN, OPTIMAL DOSING REGIMEN
COMPARATIVE ANALYSIS OF LAPAROSCOPIC CHOLECYSTECTOMY OUTCOMES IN ACUTE CALCULOUS CHOLECYSTITIS: IMPORTANCE OF INDOCYANINE GREEN, OPTIMAL DOSING REGIMEN

To cite this article:

Klimov AE, Leonovich AM, Kosachenko MV, Barkhudarov AA, Gogichashvili VV. Comparative analysis of laparoscopic cholecystectomy outcomes in acute calculous cholecystitis: importance of indocyanine green, optimal dosing regimen. Pirogov Russian Journal of Surgery. 2024;(11):72‑76. (In Russ.)
https://doi.org/10.17116/hirurgia202411172

Подписка 2026 Хирургия. Журнал им. Н.И. Пирогова (Pirogov Russian Journal of Surgery)
МСФ на ЯМ
Использование инфографики авторами научных работ
Recommended articles:
Preliminary resu­lts of fluorescent lymphography in patients with biliary cancer unde­rgoing liver rese­ction. Piro­gov Russian Journal of Surgery. 2025;(2):27-36
Abstract:

OBJECTIVE

To show the effectiveness of the indocyanine green application in laparoscopic cholecystectomy of any complexity.

MATERIAL AND METHODS

Our study used a domestically produced drug, namely indocyanine green, lyophilisate, which was diluted in water for injections. In addition, 4K equipment with the possibility of fluorescence of different manufacturers (Arthrex, ELEPS, KARL STORZ) was used. The study group included 117 patients who were urgently hospitalized with acute calculous cholecystitis diagnosis. All patients were additionally examined in the preoperative period according to the recommendations of the Ministry of Health of the Russian Federation. The control group included 109 patients. A retrospective analysis of the medical records for 2023 was carried out.

RESULTS

The advantages of using indocyanine green in the performance of laparoscopic cholecystectomy of any complexity were confirmed. The drug application promotes the extrahepatic biliary tracts navigation, thus allowing to avoid the injuries of extrahepatic bile ducts and the consequences of these injuries. In addition, its implementation increases the possibility of early training of young professionals and residents on the technique of safe laparoscopic cholecystectomy.

CONCLUSIONS

The application of optimal dosages of indocyanine does not cause visual discomfort during the operation, significantly reduces the duration of the surgery, thus allowing to reduce the time spent in the hospital in the postoperative period.

Keywords:

acute calculous cholecystitis
indocyanine green
fluorescence
safe cholecystectomy
dosage and administration routes of indocyanine green

Authors:

Klimov A.E.

Vinogradov University Clinical Hospital — Patrice Lumumba Peoples’ Friendship University of Russia

Leonovich A.M.

Vinogradov University Clinical Hospital — Patrice Lumumba Peoples’ Friendship University of Russia

Kosachenko M.V.

Vinogradov University Clinical Hospital — Patrice Lumumba Peoples’ Friendship University of Russia

Barkhudarov A.A.

Vinogradov University Clinical Hospital — Patrice Lumumba Peoples’ Friendship University of Russia

Gogichashvili V.V.

Vinogradov University Clinical Hospital — Patrice Lumumba Peoples’ Friendship University of Russia

Received:

18.08.2024

Accepted:

16.09.2024

Close metadata

References:

  1. Nuzzo G, Giuliante F, Giovannini I, Ardito F, D’Acapito F, Vellone M, Murazio M, Capelli G. Bile duct injury during laparoscopic cholecystectomy: results of an Italian national survey on 56 591 cholecystectomies. Archives of Surgery. 2005;140(10):986-992.  https://doi.org/10.1001/archsurg.140.10.986
  2. Törnqvist B, Strömberg C, Persson G, Nilsson M. Effect of intended intraoperative cholangiography and early detection of bile duct injury on survival after cholecystectomy: population based cohort study. BMJ. 2012;345:e6457. https://doi.org/10.1136/bmj.e6457
  3. Halbert C, Altieri MS, Yang J, Meng Z, Chen H, Talamini M, Pryor A, Parikh P, Telem DA. Long-term outcomes of patients with common bile duct injury following laparoscopic cholecystectomy. Surgical Endoscopy. 2016;30(10):4294-4299. https://doi.org/10.1007/s00464-016-4745-9
  4. Vettoretto N, Saronni C, Harbi A, Balestra L, Taglietti L, Giovanetti M. Critical view of safety during laparoscopic cholecystectomy. JSLS: Journal of the Society of Laparoendoscopic Surgeons. 2011;15(3):322-325.  https://doi.org/10.4293/108680811X13071180407474
  5. Schaafsma BE, Mieog JS, Hutteman M, van der Vorst JR, Kuppen PJ, Löwik CW, Frangioni JV, van de Velde CJ, Vahrmeijer AL. The clinical use of indocyanine green as a near-infrared fluorescent contrast agent for image-guided oncologic surgery. Journal of Surgical Oncology. 2011;104(3):323-332.  https://doi.org/10.1002/jso.21943
  6. Boogerd LS, Handgraaf HJ, Lam HD, Huurman VA, Farina-Sarasqueta A, Frangioni JV, van de Velde CJ, Braat AE, Vahrmeijer AL. Laparoscopic detection and resection of occult liver tumors of multiple cancer types using real-time near-infrared fluorescence guidance. Surgical Endoscopy. 2017;31(2):952-961.  https://doi.org/10.1007/s00464-016-5007-6
  7. Gilbert R. Cherrick, Samuel W. Stein, Carroll M. Leevy, Charles S. Davidson Indocyanine green: observations on its physical properties, plasma decay, and hepatic extraction. Journal of Clinical Investigation. 1960;39(4):592-600.  https://doi.org/10.1172/JCI104072
Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Contact us
If you have any questions, complaints or suggestions, please use this feedback form.
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.
Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.