Aim. To analyze the first experience of laparoscopic and robot-assisted surgery for locally advanced and generalized stomach cancer at the Burdenko Clinic of Faculty Surgery. Material and methods. Since 2011 27 laparoscopic and 2 robot-assisted operations for locally advanced and generalized stomach cancer have been performed in our hospital. Mean age of patients was 62.1±10 years. There were 19 men and 10 women. Results. There were 11 gastrectomies with abdominal esophageal resection and 18 Billroth I subtotal resections. Advanced surgery was made in 4 (13.7%) patients including 1 case of transverse colon resection and 3 cases of liver resection. Mean time of surgery was 260 min (180—380 min) in gastrectomy, 210 min (175—310 min) in subtotal resection. Mean intraoperative blood loss was 120 ml (50—220 ml). Conclusion. Minimally invasive technologies reliably reduce blood loss, rehabilitation, ICU- and hospital-stay. The quality of life after minimally invasive interventions is significantly higher compared with conventional surgery while reduced rehabilitation allows to start chemotherapy already in early postoperative period.