Aim. To demonstrate that the diagnosis and treatment of diabetes mellitus (DM) are actual today for surgical clinic because morbidity reached pandemic levels. Material and methods. We defined causality and comorbid relations of DM with some common pancreatic diseases that is especially important for abdominal surgical clinic. Pathogenesis, clinical and laboratory signs of diabetes were determined in patients with surgical pancreatic pathology. Results and conclusion. Meta-analysis of literature data and our own experience are presented in diagrams of surgical patients with hyperglycemia, ketoacidosis, hyperosmolar and lactacidemic syndromes. The main conclusion is need for pathogenetic approach and continuous clinical and laboratory monitoring.