The retrospective analysis of polytrauma with lethal outcome in 105 children showed that splenic injury had 31.4% of children. It was twice more often than liver injury, though the hemoperitoneum volume by liver injury exceeds that by spleen trauma (846.1±753.8 ml vs. 311±270.3 ml; p<0.002). The risk of death of intraabdominal bleeding by the spleen rupture is considerably low (OR 0.16; 95% CI 0.019-1.34; p=0.04). Nevertheless, the hemothorax by the spleen injury was much more significant than hemoperitoneum (977±866.9 ml vs. 311±270.3 ml; p<0.0003). The risk of death of intrathoracic bleeding by the spleen rupture is 45 times higher than of intraabdominal. The degree of splenic injury poorly correlates with the traumatic mechanism and the hemoperitoneum volume. The chances of the immediate death is considerably low (OR 0.09; 95% CI 0.0096-0.84; p<0.017). The main reasons of death by polytrauma remain brain injury, hemorrhagic shock after injury of thoracic cavity and traumatic shock.