Treatment results of 96 patients with ischemic heart disease, operated on with the use of artificial blood circulation and polycomponent anesthesia, were analyzed. The modified protocol of infusion therapy and functional tests (passive limb elevation and volume load test) were used to assess the dynamic vascular reaction among patients of the main group (n=54). Patients from the control group (n=42) received only standard infusion therapy. The use of functional test permits more individual calculation of the necessary volume to correct vascular reactions on the initial anesthesia. The simultaneous monitoring of tissue and brain oxygenation permits adequate assessment and correction of short vascular reactions during the cardiac surgery. During short vascular reactions the tissue perfusion in the absence of cardiac insufficiency changes in an inverse proportion to arterial blood pressure.