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Patiutko Iu.I.

Blokhin National Medical Research Center of Oncology

Chuchuev E.S.

Khirurgicheskoe otdelenie opukholeĭ pecheni i podzheludochnoĭ zhelezy Rossiĭskogo onkologicheskogo nauchnogo tsentra im. N.N. Blokhina RAMN, Moskva

Podluzhnyĭ D.V.

Rossiĭskiĭ onkologicheskiĭ nauchnyĭ tsentr im. N.N. Blokhina RAMN, Moskva

Agafonova M.G.

Khirurgicheskoe otdelenie opukholeĭ pecheni i podzheludochnoĭ zhelezy Nauchno-issledovatel'skogo instituta klinicheskoĭ onkologii Rossiĭskogo onkologicheskogo nauchnogo tsentra im. N.N. Blokhina RAMN, Moskva

The possibilities of surgical treatment of hepatocellular cancer in patients with liver cirrhosis

Authors:

Patiutko Iu.I., Chuchuev E.S., Podluzhnyĭ D.V., Agafonova M.G.

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Journal: Pirogov Russian Journal of Surgery. 2011;(10): 13‑19

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THE POSSIBILITIES OF SURGICAL TREATMENT OF HEPATOCELLULAR CANCER IN PATIENTS WITH LIVER CIRRHOSIS
THE POSSIBILITIES OF SURGICAL TREATMENT OF HEPATOCELLULAR CANCER IN PATIENTS WITH LIVER CIRRHOSIS

To cite this article:

Patiutko IuI, Chuchuev ES, Podluzhnyĭ DV, Agafonova MG. The possibilities of surgical treatment of hepatocellular cancer in patients with liver cirrhosis. Pirogov Russian Journal of Surgery. 2011;(10):13‑19. (In Russ.)

Подписка 2026 Хирургия. Журнал им. Н.И. Пирогова (Pirogov Russian Journal of Surgery)
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Abstract:

154 radical liver resections were performed on the reason of the hepatocellular cancer, of them 33% in patients with liver cirrhosis. Liver function was assessed using the Child-Pugh score. Liver cirrhosis and extensive liver resections proved to be the independent complication and lethality risk factors. The extensive liver resections were performed in 70%. The postoperative morbidity rate was 44.8%, the lethality was 5.8%. The concomitant liver cirrhosis reliably worsens postoperative complications (p=0.001) and lethality (p=0.0001) rates. The long-term treatment results were analyzed. Thus, liver resection proved to be an appropriate treatment for patients with hepatocellular cancer and liver cirrhosis Child-Pugh stage A, but a thorough patient selection is recommended. Liver resection is contraindicated by liver cirrhosis Child-Pugh stage B. The orthotopic liver transplantation is recommended in such cases, considering that Milan criteria are observed. The rest cases should consider the possibilities of radiofrequency ablation, transarterial chemoembolization, chemotherapy.

Keywords:

hepatocellular cancer
liver cirrhosis
liver resection

Authors:

Patiutko Iu.I.

Blokhin National Medical Research Center of Oncology

Chuchuev E.S.

Khirurgicheskoe otdelenie opukholeĭ pecheni i podzheludochnoĭ zhelezy Rossiĭskogo onkologicheskogo nauchnogo tsentra im. N.N. Blokhina RAMN, Moskva

Podluzhnyĭ D.V.

Rossiĭskiĭ onkologicheskiĭ nauchnyĭ tsentr im. N.N. Blokhina RAMN, Moskva

Agafonova M.G.

Khirurgicheskoe otdelenie opukholeĭ pecheni i podzheludochnoĭ zhelezy Nauchno-issledovatel'skogo instituta klinicheskoĭ onkologii Rossiĭskogo onkologicheskogo nauchnogo tsentra im. N.N. Blokhina RAMN, Moskva

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