Risk of infective endocarditis after aortic valve neocuspidization (Ozaki procedure): a multiple-center study

Enginoev S.T.; Chernov I.I.; Komarov R.N.; Sinelnikov Yu.S.; Semagin A.P.; Arutyunayan V.B.; Chragyan V.A.; Kadyraliyev B.K.; Pisaryuk A.S.; Ismailbaev A.M.; Kuznetsov D.V.; Zybin A.A.; Dzandukoeva P.Kh.; Tlisov B.M.; Abdurakhmanov A.A.; Tarasov D.G.

doi:https://doi.org/10.17116/kardio202215061578

Enginoev S.T.

Federal Center for Cardiovascular Surgery;
Astrakhan State Medical University

Chernov I.I.

Federal Center for Cardiovascular Surgery

Komarov R.N.

Sechenov First Moscow State Medical University

ORCID: 0000-0002-3904-6415

Sinelnikov Yu.S.

Sukhanov Federal Center for Cardiovascular Surgery

Semagin A.P.

Polyakov Samara Regional Clinical Cardiology Dispensary

Arutyunayan V.B.

Sukhanov Federal Center of Cardiovascular Surgery

Chragyan V.A.

Sukhanov Federal Center of Cardiovascular Surgery

Kadyraliyev B.K.

Sechenov First Moscow State Medical University

Pisaryuk A.S.

Peoples’ Friendship University of Russia

Ismailbaev A.M.

Sechenov First Moscow State Medical University

ORCID: 0000-0001-8545-3276

Kuznetsov D.V.

Polyakov Samara Regional Clinical Cardiology Dispensary

Zybin A.A.

Polyakov Samara Regional Clinical Cardiology Dispensary

Dzandukoeva P.Kh.

Astrakhan State Medical University

Tlisov B.M.

Sechenov First Moscow State Medical University

ORCID: 0000-0003-4094-8771

Abdurakhmanov A.A.

Astrakhan State Medical University

Tarasov D.G.

Federal Center for Cardiovascular Surgery;
Astrakhan State Medical University

Risk of infective endocarditis after aortic valve neocuspidization (Ozaki procedure): a multiple-center study

Authors:

Enginoev S.T., Chernov I.I., Komarov R.N., Sinelnikov Yu.S., Semagin A.P., Arutyunayan V.B., Chragyan V.A., Kadyraliyev B.K., Pisaryuk A.S., Ismailbaev A.M., Kuznetsov D.V., Zybin A.A., Dzandukoeva P.Kh., Tlisov B.M., Abdurakhmanov A.A., Tarasov D.G.

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Journal: Russian Journal of Cardiology and Cardiovascular Surgery. 2022;15(6): 578‑585

DOI: 10.17116/kardio202215061578

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To cite this article:

Enginoev ST, Chernov II, Komarov RN, et al. Risk of infective endocarditis after aortic valve neocuspidization (Ozaki procedure): a multiple-center study. Russian Journal of Cardiology and Cardiovascular Surgery. 2022;15(6):578‑585. (In Russ.)
https://doi.org/10.17116/kardio202215061578

Подписка 2026 Кардиология и сердечно-сосудистая хирургия (Russian Journal of Cardiology and Cardiovascular Surgery)

Использование инфографики авторами научных работ

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Abstract:

OBJECTIVE

To determine the incidence and risk factors of infective endocarditis (IE) after aortic valve neocuspidization.

MATERIAL AND METHODS

The study included 251 patients (116 men and 135 women) with aortic valve disease who underwent aortic valve neocuspidization in 4 hospitals between 2016 and 2019. The median follow-up period was 24 [17; 32] months.

RESULTS

IE occurred in 7 patients (2.8%) after aortic valve neocuspidization. Three-year freedom from IE was 96.6%, 3-year freedom from redo surgery — 94.6%, 3-year overall survival — 90.6%. Risk factors of IE were surgery for active IE (relative risk 16.5; 95% CI 2.85—95.54, p=0.002) and percutaneous coronary intervention for coronary artery disease (RR 11.6; 95% CI 2.24—60.14, p=0.003).

CONCLUSION

Aortic valve neocuspidization can potentially reduce the incidence of infectious complications in certain groups of patients. Further prospective multiple-center studies are needed to confirm this hypothesis.

Keywords:

aortic valve neocuspidization

Ozaki procedure

outcomes

infective endocarditis

incidence

risk factors

Authors:

Enginoev S.T.

Federal Center for Cardiovascular Surgery;
Astrakhan State Medical University

Chernov I.I.

Federal Center for Cardiovascular Surgery

Komarov R.N.

Sechenov First Moscow State Medical University

ORCID: 0000-0002-3904-6415

Sinelnikov Yu.S.

Sukhanov Federal Center for Cardiovascular Surgery

Semagin A.P.

Polyakov Samara Regional Clinical Cardiology Dispensary

Arutyunayan V.B.

Sukhanov Federal Center of Cardiovascular Surgery

Chragyan V.A.

Sukhanov Federal Center of Cardiovascular Surgery

Kadyraliyev B.K.

Sechenov First Moscow State Medical University

Pisaryuk A.S.

Peoples’ Friendship University of Russia

Ismailbaev A.M.

Sechenov First Moscow State Medical University

ORCID: 0000-0001-8545-3276

Kuznetsov D.V.

Polyakov Samara Regional Clinical Cardiology Dispensary

Zybin A.A.

Polyakov Samara Regional Clinical Cardiology Dispensary

Dzandukoeva P.Kh.

Astrakhan State Medical University

Tlisov B.M.

Sechenov First Moscow State Medical University

ORCID: 0000-0003-4094-8771

Abdurakhmanov A.A.

Astrakhan State Medical University

Tarasov D.G.

Federal Center for Cardiovascular Surgery;
Astrakhan State Medical University

Received:

19.01.2022

Accepted:

13.06.2022

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