It was analyzed the relation of filtration renal function and diabetes mellitus type 2 with complications and mortality after coronary artery bypass grafting (CABG). Case histories of patients who underwent CABG for the period 2006—2009 were retrospectively analyzed. Case histories of patients with diabetes mellitus type 2 were selected (n=317, median age — 59.0 years). Control group enrolled 350 patients’ case histories without diabetes and other carbohydrate metabolism disorders (median age — 58.0 years), which were comparable in gender, age, surgical characteristics of CABG. Glomerular filtration rate (GFR) was defined according to serum creatinine using CKD-EPI formula (Chronic Kidney Disease Epidemiology Collaboration). Logistic regression was used to estimate relation of possible factors with complications after CABG. It was concluded that preoperative renal function (GFR<60 ml/min/1.73 m2) was revealed more frequently in diabetes group (29.0 и 20.9% respectively, р=0.014). Incidence of complications after CABG was increased in case of diabetes mellitus type 2 (OR 1.537; р=0.011), preoperative GFR decrease on every 5 ml/min/1.73 m2 (OR 1.050; р=0.041) and augmentation of cardiopulmonary bypass time on every 5 minutes (OR 1.059; р=0.004). In other analysis independent predictors included preoperative renal dysfunction — OR 1.564, р=0.026, diabetes mellitus type 2 requiring insulinotherapy (OR 2.403; р=0.043). Besides, decrease of GFR on every 5 ml/minн/1.73 m2 was associated with increased incidence of acute renal failure after CABF (р=0.031), hospital death (р=0.026), need for renal replacement therapy (р=0.043). Also frequency of hyperglycemia 1st day after surgery and opportunity of prolonged hospital-stay were increased in case of decreased GFR (р=0.009 and р=0.013 respectively). It was concluded that diabetes mellitus type 2 and GFR are predictors of postoperative complications after CABG. Risk of acute renal failure, hyperglycemia after CABG, need for renal replacement therapy and mortality are increased in case of decreased GFR.