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Lomivorotov V.V.

E.N.Meshalkin National Medical Research Center under the Ministry of Health of the Russia, Novosibirsk, 630055, Russia

Shmyrev V.A.

FGBU "Novosibirskiĭ nauchno-issledovatel'skiĭ institut patologii krovoobrashcheniia im. akad. E.N. Meshalkina" Minzdrava Rossii

Ponomarev D.N.

FGBU "Novosibirskiĭ nauchno-issledovatel'skiĭ institut patologii krovoobrashcheniia im. akad. E.N. Meshalkina" Minzdrava Rossii

Efremov S.M.

FGBU "NNIIPK im. akad. E.N. Meshalkina" Minzdrava Rossii, Novosibirsk

Shilova A.N.

Department of Vascular Surgery, E.N. Meshalkin Novosibirsk Research Institute of Circulation Pathology, Novosibirsk

Impact of distant ischemic preconditioning on oxidative stress in cardiosurgical patients

Authors:

Lomivorotov V.V., Shmyrev V.A., Ponomarev D.N., Efremov S.M., Shilova A.N.

More about the authors

Journal: Russian Journal of Cardiology and Cardiovascular Surgery. 2013;6(4): 49‑54

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Table of contents

IMPACT OF DISTANT ISCHEMIC PRECONDITIONING ON OXIDATIVE STRESS IN CARDIOSURGICAL PATIENTS
IMPACT OF DISTANT ISCHEMIC PRECONDITIONING ON OXIDATIVE STRESS IN CARDIOSURGICAL PATIENTS

To cite this article:

Lomivorotov VV, Shmyrev VA, Ponomarev DN, Efremov SM, Shilova AN. Impact of distant ischemic preconditioning on oxidative stress in cardiosurgical patients. Russian Journal of Cardiology and Cardiovascular Surgery. 2013;6(4):49‑54. (In Russ.)

Подписка 2025-2 (Russian Journal of Cardiology and Cardiovascular Surgery)
 
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Impact of distant ischemic preconditioning (DIP) on development of oxidative stress and severity of myocardial injury was studied in 88 patients undergoing myocardial revascularization under artificial circulation. In DIP group patients three times during 5 minutes underwent cuff inflation on the shoulder (up to 200 mm Hg) for non-invasive estimation of blood pressure with further reperfusion during 5 minutes. It is shown that DIP doesn't have any impact on degree of myocardial injury and oxidative stress in patients with normal myocardial contractility and without severe concomitant diseases undergoing myocardial revascularization under artificial circulation. It is ascertained that plasma level of peroxide on the first day after operation is an independent prognostic factor for prolonged hospitalization.

Keywords:

myocardial revascularization
artificial circulation
reperfusion
oxidative stress
distant ischemic preconditioning

Authors:

Lomivorotov V.V.

E.N.Meshalkin National Medical Research Center under the Ministry of Health of the Russia, Novosibirsk, 630055, Russia

Shmyrev V.A.

FGBU "Novosibirskiĭ nauchno-issledovatel'skiĭ institut patologii krovoobrashcheniia im. akad. E.N. Meshalkina" Minzdrava Rossii

Ponomarev D.N.

FGBU "Novosibirskiĭ nauchno-issledovatel'skiĭ institut patologii krovoobrashcheniia im. akad. E.N. Meshalkina" Minzdrava Rossii

Efremov S.M.

FGBU "NNIIPK im. akad. E.N. Meshalkina" Minzdrava Rossii, Novosibirsk

Shilova A.N.

Department of Vascular Surgery, E.N. Meshalkin Novosibirsk Research Institute of Circulation Pathology, Novosibirsk

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