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Chumakova S.P.

GBOU VPO Sibirskiĭ gosudarstvennyĭ meditsinskiĭ universitet Minzdravsotsrazvitiia Rossii

Shipulin V.M.

Cardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk, Russia;
Siberian State Medical University, Tomsk, Russia

Urazova O.I.

Sibirskiĭ gosudarstvennyĭ meditsinskiĭ universitet, Tomsk

Novitskiĭ V.V.

GBOU VPO Sibirskiĭ gosudarstvennyĭ meditsinskiĭ universitet Minzdravsotsrazvitiia Rossii

Amrisheva Z.K.

Uchrezhdenie RAMN NII kardiologii SO RAMN, Tomsk

Mal'tseva I.V.

GBOU VPO Sibirskiĭ gosudarstvennyĭ meditsinskiĭ universitet Minzdravsotsrazvitiia Rossii

Emel'ianova T.V.

NII kardiologii SO RAMN, Tomsk

Saprykina É.V.

GBOU VPO Sibirskiĭ gosudarstvennyĭ meditsinskiĭ universitet Minzdravsotsrazvitiia Rossii

Antioxidant potential of erythrocytes and blood plasma in coronary patients with moderate and marked hemolysis after operations under artificial circulation

Authors:

Chumakova S.P., Shipulin V.M., Urazova O.I., Novitskiĭ V.V., Amrisheva Z.K., Mal'tseva I.V., Emel'ianova T.V., Saprykina É.V.

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Journal: Russian Journal of Cardiology and Cardiovascular Surgery. 2012;5(6): 95‑99

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Table of contents

ANTIOXIDANT POTENTIAL OF ERYTHROCYTES AND BLOOD PLASMA IN CORONARY PATIENTS WITH MODERATE AND MARKED HEMOLYSIS AFTER OPERATIONS UNDER ARTIFICIAL CIRCULATION
ANTIOXIDANT POTENTIAL OF ERYTHROCYTES AND BLOOD PLASMA IN CORONARY PATIENTS WITH MODERATE AND MARKED HEMOLYSIS AFTER OPERATIONS UNDER ARTIFICIAL CIRCULATION

To cite this article:

Chumakova SP, Shipulin VM, Urazova OI, et al. . Antioxidant potential of erythrocytes and blood plasma in coronary patients with moderate and marked hemolysis after operations under artificial circulation. Russian Journal of Cardiology and Cardiovascular Surgery. 2012;5(6):95‑99. (In Russ.)

Подписка 2025-2 (Russian Journal of Cardiology and Cardiovascular Surgery)
 
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Indices of antioxidant protection system were studied in cardiosurgical patients with moderate (40 patients) and marked (18 patients) hemolysis after coronary artery bypass grafting carried out under artificial circulation. Before and after the operation investigators studied concentration of free hemoglobin and general antioxidant activity in blood plasma, level of reaction products with thiobarbituric acid (TBA) in blood plasma and erythrocytes, catalase and superoxide dismutase activity in erythrocytes as well as the content of reticulocytes in blood. It was estimated that development of marked hemolysis is associated with the higher content of reticulocytes in blood compared with moderate hemolysis and low catalase activity in erythrocytes before the operation as well as with increased superoxide dismutase activity and content of TBA-active products in erythrocytes after artificial circulation, conditioned by a short-term rise of рО2 for more than 200 mmHg in blood during perfusion. Antioxidant potential of blood plasma doesn't impact variability of postoperative hemoglobinemia.

Keywords:

hemolysis
antioxidants
erythrocytes
artificial circulation
lipid peroxidation

Authors:

Chumakova S.P.

GBOU VPO Sibirskiĭ gosudarstvennyĭ meditsinskiĭ universitet Minzdravsotsrazvitiia Rossii

Shipulin V.M.

Cardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk, Russia;
Siberian State Medical University, Tomsk, Russia

Urazova O.I.

Sibirskiĭ gosudarstvennyĭ meditsinskiĭ universitet, Tomsk

Novitskiĭ V.V.

GBOU VPO Sibirskiĭ gosudarstvennyĭ meditsinskiĭ universitet Minzdravsotsrazvitiia Rossii

Amrisheva Z.K.

Uchrezhdenie RAMN NII kardiologii SO RAMN, Tomsk

Mal'tseva I.V.

GBOU VPO Sibirskiĭ gosudarstvennyĭ meditsinskiĭ universitet Minzdravsotsrazvitiia Rossii

Emel'ianova T.V.

NII kardiologii SO RAMN, Tomsk

Saprykina É.V.

GBOU VPO Sibirskiĭ gosudarstvennyĭ meditsinskiĭ universitet Minzdravsotsrazvitiia Rossii

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