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Krymukova M.A.

Chazov National Medical Research Centre of Cardiology

Mironov N.Yu.

Chazov National Medical Research Centre of Cardiology;
Plekhanov Russian University of Economics

Dzaurova K.M.

Chazov National Medical Research Centre of Cardiology

Yuricheva Yu.A.

Chazov National Medical Research Centre of Cardiology

Belyaeva M.M.

Chazov National Medical Research Centre of Cardiology

Sviridova V.V.

Chazov National Medical Research Centre of Cardiology

Sokolov S.F.

Chazov National Medical Research Centre of Cardiology

Golitsyn S.P.

Chazov National Medical Research Centre of Cardiology

Refralon for drug-induced cardioversion of atrial fibrillation in patients with coronary artery disease

Authors:

Krymukova M.A., Mironov N.Yu., Dzaurova K.M., Yuricheva Yu.A., Belyaeva M.M., Sviridova V.V., Sokolov S.F., Golitsyn S.P.

More about the authors

Journal: Russian Cardiology Bulletin. 2024;19(4‑2): 188‑196

DOI: 10.17116/Cardiobulletin202419042188

Read: 1258 times

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Table of contents

REFRALON FOR DRUG-INDUCED CARDIOVERSION OF ATRIAL FIBRILLATION IN PATIENTS WITH CORONARY ARTERY DISEASE
REFRALON FOR DRUG-INDUCED CARDIOVERSION OF ATRIAL FIBRILLATION IN PATIENTS WITH CORONARY ARTERY DISEASE

To cite this article:

Krymukova MA, Mironov NYu, Dzaurova KM, et al. . Refralon for drug-induced cardioversion of atrial fibrillation in patients with coronary artery disease. Russian Cardiology Bulletin. 2024;19(4‑2):188‑196. (In Russ.)
https://doi.org/10.17116/Cardiobulletin202419042188

ЭндоКард
Подписка 2026 Кардиологический вестник (Russian Cardiology Bulletin)
 
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

Atrial fibrillation (AF) is the leading cause of morbidity and hospitalizations among all cardiac arrhythmias. Moreover, the number of patients with coronary artery disease and other structural heart diseases leading to atrial remodeling increases that predisposes to arrhythmia. Patients with concomitant cardiovascular diseases are more prone to AF-related complications including tachycardia-induced cardiomyopathy. That is why restoration of sinus rhythm is essential in management of these patients. According to clinical guidelines, amiodarone is the only antiarrhythmic drug approved for cardioversion of AF in patients with structural heart diseases. Preliminary results of randomized trial demonstrated superiority of class III drug Refralon (cavutilide) over amiodarone. However, Refralon has not been studied in patients with concomitant structural heart diseases. We analyze 3 successful pharmacological cardioversions by administration of Refralon in patients with atrial fibrillation, coronary artery disease, previous myocardial infarction and moderately reduced ejection fraction.

Keywords:

atrial fibrillation
pharmacological cardioversion
antiarrhythmic drugs
refralon
coronary artery disease

Authors:

Krymukova M.A.

Chazov National Medical Research Centre of Cardiology

Mironov N.Yu.

Chazov National Medical Research Centre of Cardiology;
Plekhanov Russian University of Economics

Dzaurova K.M.

Chazov National Medical Research Centre of Cardiology

Yuricheva Yu.A.

Chazov National Medical Research Centre of Cardiology

Belyaeva M.M.

Chazov National Medical Research Centre of Cardiology

Sviridova V.V.

Chazov National Medical Research Centre of Cardiology

Sokolov S.F.

Chazov National Medical Research Centre of Cardiology

Golitsyn S.P.

Chazov National Medical Research Centre of Cardiology

Received:

06.02.2024

Accepted:

22.04.2024

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